ENSBTAP00000037032-D1 (Bos grunniens)
C2H2 ZF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source
PF00096 (zf-C2H2) IPR007087 ENSBTAP00000037032-D1 T134641_2.00 GigaDB (2015-Oct-22)
NCBI Gene Info:
This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277). [provided by RefSeq, Dec 2016]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
ZNF3
M07613_2.00
Homo sapiens
TCWNTYAKTCADTCA

TGAHTGAMTRANWGA
ChIP-seq+ChIP-exo
Barazandeh et al.(2018)
ZNF3.RCADE.ReprocessedData
0.768 0.962
For this family, TFs with SR scores > 0.755 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSBTAP00000037032-D1 C2H2 ZF 211 233
ENSBTAP00000037032-D1 C2H2 ZF 239 261
ENSBTAP00000037032-D1 C2H2 ZF 267 289
ENSBTAP00000037032-D1 C2H2 ZF 295 317
ENSBTAP00000037032-D1 C2H2 ZF 323 344
ENSBTAP00000037032-D1 C2H2 ZF 350 372
ENSBTAP00000037032-D1 C2H2 ZF 378 400
ENSBTAP00000037032-D1 C2H2 ZF 406 428

Links

Other C2H2 ZF family TFs
Other Bos grunniens TFs

35 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action
ZNF3 Microcebus murinus ENSMICG00000003962 I 0.771
ZNF3 Pteropus vampyrus ENSPVAG00000005182 I 0.771
ENSAMEG00000011233 Ailuropoda melanoleuca ENSAMEG00000011233 I 0.771
ENSOARG00000017937 Ovis aries ENSOARG00000017937 I 0.771
ZNF3 Ochotona princeps ENSOPRG00000003308 I 0.771
ZNF3 Otolemur garnettii ENSOGAG00000006409 I 0.771
ZNF3 Tupaia belangeri ENSTBEG00000013905 I 0.771
ZNF3 Felis catus ENSFCAG00000003560 I 0.771
ZNF3 Canis familiaris ENSCAFG00000018472 I 0.771
ZNF3 Bos taurus ENSBTAG00000007012 I 0.771
ZNF3 Cavia porcellus ENSCPOG00000010860 I 0.771
ZNF3 Tursiops truncatus ENSTTRG00000012311 I 0.771
ENSTSYG00000013704 Tarsius syrichta ENSTSYG00000013704 I 0.771
ZNF3 Oryctolagus cuniculus ENSOCUG00000005390 I 0.770
ENSSTOG00000028734 Ictidomys tridecemlineatus ENSSTOG00000028734 I 0.770
ZNF3 Myotis lucifugus ENSMLUG00000004466 I 0.770
ZNF3 Procavia capensis ENSPCAG00000015736 I 0.770
ZNF3 Dasypus novemcinctus ENSDNOG00000010382 I 0.770
ZNF3 Loxodonta africana ENSLAFG00000014618 I 0.770
ZNF3 Equus caballus ENSECAG00000024649 I 0.770
ENSP00000415358 Macaca fascicularis ENSP00000415358 I 0.768
ZNF3 Pan troglodytes ENSPTRG00000019470 I 0.768
ENSPPYG00000017396 Pongo abelii ENSPPYG00000017396 I 0.768
ENSSHAG00000011938 Sarcophilus harrisii ENSSHAG00000011938 I 0.768
ZNF3 Macaca mulatta ENSMMUG00000004021 I 0.768
Zfp113 Dipodomys ordii ENSDORG00000000945 I 0.768
ENSCSAG00000017832 Chlorocebus sabaeus ENSCSAG00000017832 I 0.768
ZNF3 Callithrix jacchus ENSCJAG00000015656 I 0.768
ZNF3 Erinaceus europaeus ENSEEUG00000003422 I 0.768
ZNF3 Homo sapiens ENSG00000166526 D 0.768
ZNF3 Monodelphis domestica ENSMODG00000004159 I 0.768
ENSMEUG00000013213 Macropus eugenii ENSMEUG00000013213 I 0.768
ENSPANG00000011255 Papio anubis ENSPANG00000011255 I 0.768
ENSMPUG00000010891 Mustela putorius furo ENSMPUG00000010891 I 0.767
ZNF3 Echinops telfairi ENSETEG00000002679 I 0.759