ENSP00000228437 (Macaca fascicularis)
C2H2 ZF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source
PF00096 (zf-C2H2) IPR007087 ENSP00000228437 T134902_2.00 GigaDB (2015-Oct-22)
NCBI Gene Info:
The protein encoded by this gene is a transcription factor of the PR-domain protein family. It contains a PR-domain and multiple zinc finger motifs. Transcription factors of the PR-domain family are known to be involved in cell differentiation and tumorigenesis. An elevated expression level of this gene has been observed in PC12 cells treated with nerve growth factor, beta polypeptide (NGF). This gene is located in a chromosomal region that is thought to contain tumor suppressor genes. [provided by RefSeq, Jul 2008]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
PRDM4
M02881_2.00 		Homo sapiens
TTTCAAGGCCCCC
GGGGGCCTTGAAA		 SELEX
Jolma et al.(2013)
PRDM4_1 		0.827 1.000
PRDM4
M04421_2.00 		Homo sapiens
YRRCNGTTTCAAGKCYMCCC
GGGKRGMCTTGAAACNGYYR		 SELEX
Yin et al.(2017)
PRDM4_eDBD_HT-SELEX 		0.827 1.000
PRDM4
M04422_2.00 		Homo sapiens
YRGCRGTTTCRAGGSTTVCC
GGBAASCCTYGAAACYGCYR		 SELEX
Yin et al.(2017)
PRDM4_eDBD_Methyl-HT-SELEX_1 		0.827 1.000
PRDM4
M04423_2.00 		Homo sapiens
YRRCRGTTTCRAGKSYNCCC
GGGNRSMCTYGAAACYGYYR		 SELEX
Yin et al.(2017)
PRDM4_eDBD_Methyl-HT-SELEX_2 		0.827 1.000
For this family, TFs with SR scores > 0.755 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000228437 C2H2 ZF 587 609
ENSP00000228437 C2H2 ZF 615 637
ENSP00000228437 C2H2 ZF 643 665
ENSP00000228437 C2H2 ZF 671 693
ENSP00000228437 C2H2 ZF 699 721
ENSP00000228437 C2H2 ZF 727 748

Links

Other C2H2 ZF family TFs
Other Macaca fascicularis TFs

Invalid Input OrderBy

53 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action