ENSP00000285407 (Macaca fascicularis)
C2H2 ZF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source
PF00096 (zf-C2H2) IPR007087 ENSP00000285407 T134979_2.00 GigaDB (2015-Oct-22)
NCBI Gene Info:
This gene encodes a member of a family of proteins that feature C2H2-type zinc finger domains. The encoded protein is a transcriptional repressor that acts as an effector of transforming growth factor beta signaling. Activity of this protein may inhibit the growth of cancers, particularly pancreatic cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
KLF10
M04489_2.00 		Homo sapiens
RMCACRCCCMYVHCACRCCCMC
GKGGGYGTGDBRKGGGYGTGKY		 SELEX
Yin et al.(2017)
KLF10_eDBD_HT-SELEX 		0.827 1.000
KLF10
M08246_2.00 		Homo sapiens
RCCMCRCCCH
DGGGYGKGGY		 ChIP-seq
Najafabadi et al.(2015b)
KLF10 		0.827 1.000
KLF10
M08317_2.00 		Homo sapiens
SMCMCRCCCMYNBSN
NSVNRKGGGYGKGKS		 ChIP-seq
Schmitges et al.(2016)
Q13118.MEME 		0.827 1.000
KLF10
M10228_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$TIEG1_Q6 		0.827 1.000
KLF10
M04490_2.00 		Homo sapiens
RMCACRCCCMYGMCACRCCCHC
GDGGGYGTGKCRKGGGYGTGKY		 SELEX
Yin et al.(2017)
KLF10_eDBD_Methyl-HT-SELEX 		0.827 1.000
KLF11
M00242_2.00 		Homo sapiens
MCGCCCCC
GGGGGCGK		 PBM
Barrera et al.(2016)
KLF11_REF 		0.775 0.855
KLF11
M04554_2.00 		Homo sapiens
VMCMCRCCCMYNMCACGCCCMC
GKGGGCGTGKNRKGGGYGKGKB		 SELEX
Yin et al.(2017)
KLF11_eDBD_HT-SELEX 		0.775 0.855
KLF11
M10261_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$FKLF_Q5 		0.775 0.855
KLF11
M00241_2.00 		Homo sapiens
MCGCCCMC
GKGGGCGK		 PBM
Barrera et al.(2016)
KLF11_R402Q 		0.775 0.855
KLF11
M04555_2.00 		Homo sapiens
VMCMCRCCCHYNHCACGCCCMC
GKGGGCGTGDNRDGGGYGKGKB		 SELEX
Yin et al.(2017)
KLF11_eDBD_Methyl-HT-SELEX 		0.775 0.855
For this family, TFs with SR scores > 0.755 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000285407 C2H2 ZF 367 393
ENSP00000285407 C2H2 ZF 399 423
ENSP00000285407 C2H2 ZF 429 451

Links

Other C2H2 ZF family TFs
Other Macaca fascicularis TFs

Invalid Input OrderBy

158 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action