ENSP00000292928 (Macaca fascicularis)
C2H2 ZF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source
PF00096 (zf-C2H2) IPR007087 ENSP00000292928 T134991_2.00 GigaDB (2015-Oct-22)
NCBI Gene Info:
This gene encodes a KRAB domain zinc finger transcription factor (KZNF). KZNFs play critical roles in the regulation of many cellular processes including differentiation, proliferation and apoptosis. The encoded protein inhibits activating protein 1 (AP-1) and nuclear factor kappa-B (NF-kB) signaling and may function as a tumor suppressor in multiple carcinomas. This gene is found in a cluster with other zinc finger protein genes on the long arm of chromosome 19, and alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2012]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
ZNF382
M08319_2.00
Homo sapiens
SHVYDDKRYCTGTASTRNTKBCWC

GWGVMANYASTACAGRYMHHRBDS
ChIP-seq
Schmitges et al.(2016)
Q96SR6_1-8.RCADE
0.827 1.000
ZNF382
M07608_2.00
Homo sapiens
NDKKDHCTGTRSTRNTKBCTC

GAGVMANYASYACAGDHMMHN
ChIP-seq+ChIP-exo
Barazandeh et al.(2018)
ZNF382.RCADE.OriginalMapping
0.827 1.000
ZNF382
M08247_2.00
Homo sapiens
NNNDMTAACAHNNNN

NNNNDTGTTAKHNNN
ChIP-seq
Najafabadi et al.(2015b)
ZNF382
0.827 1.000
ZNF382
M08904_2.00
Homo sapiens
RTDGKRTCTGTWGTRRTGBCYC

GRGVCAYYACWACAGAYMCHAY
Misc
Kulakovskiy et al.(2013)
ZN382_HUMAN.H11MO.0.C
0.827 1.000
Zfp382
M10363_2.00
Rattus norvegicus Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$ZFP382_04
0.770 0.902
For this family, TFs with SR scores > 0.755 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000292928 C2H2 ZF 296 318
ENSP00000292928 C2H2 ZF 324 346
ENSP00000292928 C2H2 ZF 352 374
ENSP00000292928 C2H2 ZF 380 402
ENSP00000292928 C2H2 ZF 408 430
ENSP00000292928 C2H2 ZF 436 458
ENSP00000292928 C2H2 ZF 464 486
ENSP00000292928 C2H2 ZF 494 514
ENSP00000292928 C2H2 ZF 520 542

Links

Other C2H2 ZF family TFs
Other Macaca fascicularis TFs

34 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action
ZNF382 Homo sapiens ENSG00000161298 D 0.827
ENSNLEG00000003063 Nomascus leucogenys ENSNLEG00000003063 I 0.827
ZNF382 Gorilla gorilla ENSGGOG00000009292 I 0.827
ENSPANG00000010969 Papio anubis ENSPANG00000010969 I 0.827
ZNF382 Macaca mulatta ENSMMUG00000016449 I 0.827
ZNF382 Pan troglodytes ENSPTRG00000010898 I 0.827
ENSPPYG00000009904 Pongo abelii ENSPPYG00000009904 I 0.827
ENSCSAG00000004201 Chlorocebus sabaeus ENSCSAG00000004201 I 0.827
ENSTSYG00000014470 Tarsius syrichta ENSTSYG00000014470 I 0.824
ZNF382 Callithrix jacchus ENSCJAG00000009464 I 0.822
ZNF382 Otolemur garnettii ENSOGAG00000025946 I 0.819
ZNF382 Vicugna pacos ENSVPAG00000009825 I 0.818
ENSOARG00000005318 Ovis aries ENSOARG00000005318 I 0.818
ZNF382 Canis familiaris ENSCAFG00000006524 I 0.818
ZNF382 Felis catus ENSFCAG00000026545 I 0.818
ZNF382 Tursiops truncatus ENSTTRG00000001414 I 0.818
ZNF382 Sorex araneus ENSSARG00000009413 I 0.817
ENSMPUG00000005592 Mustela putorius furo ENSMPUG00000005592 I 0.817
ZNF382 Bos taurus ENSBTAG00000008084 I 0.817
ZNF382 Loxodonta africana ENSLAFG00000011372 I 0.817
ZNF382 Equus caballus ENSECAG00000018834 I 0.815
ZNF382 Choloepus hoffmanni ENSCHOG00000004936 I 0.814
ENSSTOG00000021574 Ictidomys tridecemlineatus ENSSTOG00000021574 I 0.813
ZNF382 Sus scrofa ENSSSCG00000002933 I 0.811
ZNF382 Dasypus novemcinctus ENSDNOG00000032742 I 0.810
ZNF382 Pteropus vampyrus ENSPVAG00000014052 I 0.808
ENSDORG00000016099 Dipodomys ordii ENSDORG00000016099 I 0.807
ZNF382 Myotis lucifugus ENSMLUG00000015074 I 0.803
ZNF382 Cavia porcellus ENSCPOG00000002209 I 0.802
Myotis_brandtii_ZNF382_10004803 Myotis brandtii Myotis_brandtii_ZNF382_10004803 I 0.799
ZNF382 Tupaia belangeri ENSTBEG00000005166 I 0.799
ZNF382 Procavia capensis ENSPCAG00000004980 I 0.786
Zfp382 Mus musculus ENSMUSG00000074220 I 0.781
Zfp382 Rattus norvegicus ENSRNOG00000020777 D 0.770