ENSP00000299466-D1 (Bos grunniens)
C2H2 ZF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source
PF00096 (zf-C2H2) IPR007087 ENSP00000299466-D1 T135005_2.00 GigaDB (2015-Oct-22)
NCBI Gene Info:
This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277). [provided by RefSeq, Dec 2016]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
No TFs with similar DNA binding domains

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000299466-D1 C2H2 ZF 70 92
ENSP00000299466-D1 C2H2 ZF 98 120
ENSP00000299466-D1 C2H2 ZF 334 355
ENSP00000299466-D1 C2H2 ZF 361 383
ENSP00000299466-D1 C2H2 ZF 393 415
ENSP00000299466-D1 C2H2 ZF 639 661
ENSP00000299466-D1 C2H2 ZF 667 689
ENSP00000299466-D1 C2H2 ZF 775 797
ENSP00000299466-D1 C2H2 ZF 803 825

Links

Other C2H2 ZF family TFs
Other Bos grunniens TFs

40 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action
SALL3 Sus scrofa ENSSSCG00000004858 N 0.826
ENSOARG00000004353 Ovis aries ENSOARG00000004353 N 0.814
Sall3 Rattus norvegicus ENSRNOG00000026116 N 0.812
ENSCSAG00000018244 Chlorocebus sabaeus ENSCSAG00000018244 N 0.811
SALL3 Macaca mulatta ENSMMUG00000000286 N 0.811
SALL3 Gorilla gorilla ENSGGOG00000008127 N 0.811
SALL3 Otolemur garnettii ENSOGAG00000031681 N 0.811
SALL3 Callithrix jacchus ENSCJAG00000007332 N 0.811
SALL3 Homo sapiens ENSG00000256463 N 0.811
Tal_R008175 Tyto alba Tal_R008175 N 0.810
Alligator_sinensis_CCG003694.1 Alligator sinensis Alligator_sinensis_CCG003694.1 N 0.810
Brh_R007854 Buceros rhinoceros Brh_R007854 N 0.810
Ogr15828 Ophisaurus gracilis Ogr15828 N 0.810
Gfo_R000617 Geospiza fortis Gfo_R000617 N 0.810
Afo_R009325 Aptenodytes forsteri Afo_R009325 N 0.810
SALL3 Myotis lucifugus ENSMLUG00000010582 N 0.806
Myotis_brandtii_Sall3_10034211 Myotis brandtii Myotis_brandtii_Sall3_10034211 N 0.806
SALL3 Loxodonta africana ENSLAFG00000013521 N 0.805
Cmyd_10010411 Chelonia mydas Cmyd_10010411 N 0.805
XP_002936493 Xenopus tropicalis XP_002936493 N 0.804
XP_002936494 Xenopus tropicalis XP_002936494 N 0.804
XP_002936495 Xenopus tropicalis XP_002936495 N 0.804
SALL3 Procavia capensis ENSPCAG00000006522 N 0.802
SALL3 Dasypus novemcinctus ENSDNOG00000025483 N 0.801
ENSNLEG00000008217 Nomascus leucogenys ENSNLEG00000008217 N 0.779
Sall3 Dipodomys ordii ENSDORG00000002702 N 0.778
SALL1 Ornithorhynchus anatinus ENSOANG00000013399 N 0.770
sall1 Xenopus tropicalis XB-GENE-491393 N 0.765
SALL1 Otolemur garnettii ENSOGAG00000027316 N 0.765
Sall1 Rattus norvegicus ENSRNOG00000013907 N 0.765
sall1.L Xenopus laevis XB-GENE-866060 N 0.764
sall1a Tetraodon nigroviridis ENSTNIG00000004257 N 0.763
sall1a Takifugu rubripes ENSTRUG00000008950 N 0.763
ENSONIG00000002831 Oreochromis niloticus ENSONIG00000002831 N 0.763
SALL3 Pteropus vampyrus ENSPVAG00000014645 N 0.757
ENSLOCG00000007283 Lepisosteus oculatus ENSLOCG00000007283 N 0.757
ENSPFOG00000015799 Poecilia formosa ENSPFOG00000015799 N 0.756
sall1a Gasterosteus aculeatus ENSGACG00000016702 N 0.756
sall1a Oryzias latipes ENSORLG00000013827 N 0.756
ENSXMAG00000016273 Xiphophorus maculatus ENSXMAG00000016273 N 0.756