ENSP00000349723 (Macaca fascicularis)
C2H2 ZF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source
PF00096 (zf-C2H2) IPR007087 ENSP00000349723 T135239_2.00 GigaDB (2015-Oct-22)
NCBI Gene Info:
This gene encodes a C2H2-type zinc finger protein and is closely related to BCL11A, a gene whose translocation may be associated with B-cell malignancies. Although the specific function of this gene has not been determined, the encoded protein is known to be a transcriptional repressor, and is regulated by the NURD nucleosome remodeling and histone deacetylase complex. Four alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Aug 2013]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
BCL11B
M04453_2.00
Homo sapiens
GTGAACGBNDNNVCTACAC

GTGTAGBNNHNVCGTTCAC
SELEX
Yin et al.(2017)
BCL11B_eDBD_HT-SELEX
0.823 0.991
BCL11B
M04454_2.00
Homo sapiens
GTGAACGBNDNHVCTACAC

GTGTAGBDNHNVCGTTCAC
SELEX
Yin et al.(2017)
BCL11B_eDBD_Methyl-HT-SELEX
0.823 0.991
BCL11A
M07926_2.00
Homo sapiens
BTYTCASTTCCYYHH

DDRRGGAASTGARAV
ChIP-seq
Gerstein et al.(2012)
GM12878_BCL11A_HudsonAlpha
0.802 0.938
BCL11A
M08881_2.00
Homo sapiens
BHBYCABTTCCYBHNYN

NRNDVRGGAAVTGRVDV
Misc
Kulakovskiy et al.(2013)
BC11A_HUMAN.H11MO.0.A
0.802 0.938
BCL11A
M10187_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$BCL11A_02
0.802 0.938
For this family, TFs with SR scores > 0.755 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000349723 C2H2 ZF 338 359
ENSP00000349723 C2H2 ZF 365 386
ENSP00000349723 C2H2 ZF 391 413
ENSP00000349723 C2H2 ZF 419 441
ENSP00000349723 C2H2 ZF 449 472

Links

Other C2H2 ZF family TFs
Other Macaca fascicularis TFs

127 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action
ENSPPYG00000006131 Pongo abelii ENSPPYG00000006131 I 0.823
ENSPANG00000004313 Papio anubis ENSPANG00000004313 I 0.823
BCL11B Otolemur garnettii ENSOGAG00000033204 I 0.823
ENSPSIG00000013079 Pelodiscus sinensis ENSPSIG00000013079 I 0.823
BCL11B Pan troglodytes ENSPTRG00000006707 I 0.823
BCL11B Pteropus vampyrus ENSPVAG00000015516 I 0.823
BCL11B Dasypus novemcinctus ENSDNOG00000012677 I 0.823
BCL11B Ornithorhynchus anatinus ENSOANG00000014770 I 0.823
BCL11B Homo sapiens ENSG00000127152 D 0.823
BCL11B Loxodonta africana ENSLAFG00000009254 I 0.823
ENSGALG00000011127 Gallus gallus ENSGALG00000011127 I 0.823
ENSGALG00000028278 Gallus gallus ENSGALG00000028278 I 0.823
BCL11B Macaca mulatta ENSMMUG00000003261 I 0.823
BCL11B Monodelphis domestica ENSMODG00000012964 I 0.823
ENSNLEG00000000711 Nomascus leucogenys ENSNLEG00000000711 I 0.823
Bcl11b Mus musculus ENSMUSG00000048251 I 0.823
Bcl11b Rattus norvegicus ENSRNOG00000005776 I 0.823
ENSSHAG00000009291 Sarcophilus harrisii ENSSHAG00000009291 I 0.823
Afo_R004626 Aptenodytes forsteri Afo_R004626 I 0.823
ENSAMXG00000015839 Astyanax mexicanus ENSAMXG00000015839 I 0.823
Aan_R000616 Calypte anna Aan_R000616 I 0.823
Cmyd_10012109 Chelonia mydas Cmyd_10012109 I 0.823
Gfo_R006733 Geospiza fortis Gfo_R006733 I 0.823
Pvit_09536 Pogona vitticeps Pvit_09536 I 0.823
ENSACAG00000013085 Anolis carolinensis ENSACAG00000013085 I 0.823
ENSAPLG00000006283 Anas platyrhynchos ENSAPLG00000006283 I 0.823
BCL11B Taeniopygia guttata ENSTGUG00000012711 I 0.823
BCL11B Sus scrofa ENSSSCG00000002507 I 0.823
ENSCPOG00000009946 Cavia porcellus ENSCPOG00000009946 I 0.823
ENSCSAG00000010477 Chlorocebus sabaeus ENSCSAG00000010477 I 0.823
ENSSTOG00000021531 Ictidomys tridecemlineatus ENSSTOG00000021531 I 0.823
BCL11B Callithrix jacchus ENSCJAG00000006713 I 0.823
BCL11B Bos taurus ENSBTAG00000018019 I 0.823
BCL11B Canis familiaris ENSCAFG00000017809 I 0.823
BCL11B Gorilla gorilla ENSGGOG00000001232 I 0.823
im:7142702 Oryzias latipes ENSORLG00000010488 I 0.821
ENSAMXG00000018130 Astyanax mexicanus ENSAMXG00000018130 I 0.819
im:7142702 Gasterosteus aculeatus ENSGACG00000005537 I 0.819
ENSXMAG00000019910 Xiphophorus maculatus ENSXMAG00000019910 I 0.819
ENSPFOG00000003609 Poecilia formosa ENSPFOG00000003609 I 0.819
im:7142702 Danio rerio ENSDARG00000067727 I 0.819
BCL11B Tursiops truncatus ENSTTRG00000012140 I 0.818
im:7142702 Takifugu rubripes ENSTRUG00000018074 I 0.817
ENSONIG00000001067 Oreochromis niloticus ENSONIG00000001067 I 0.817
Sakowv30026316m.g Saccoglossus kowalevskii Sakowv30026316m.g I 0.816
ENSPFOG00000007224 Poecilia formosa ENSPFOG00000007224 I 0.815
bcl11ba Gasterosteus aculeatus ENSGACG00000013118 I 0.815
ENSXMAG00000020344 Xiphophorus maculatus ENSXMAG00000020344 I 0.815
ENSGMOG00000012414 Gadus morhua ENSGMOG00000012414 I 0.815
bcl11ba Takifugu rubripes ENSTRUG00000003531 I 0.813
ENSLOCG00000008679 Lepisosteus oculatus ENSLOCG00000008679 I 0.813
ENSONIG00000011060 Oreochromis niloticus ENSONIG00000011060 I 0.813
bcl11ba Oryzias latipes ENSORLG00000010826 I 0.813
bcl11ba Tetraodon nigroviridis ENSTNIG00000008283 I 0.813
ENSGMOG00000015842 Gadus morhua ENSGMOG00000015842 I 0.812
ENSLOCG00000016135 Lepisosteus oculatus ENSLOCG00000016135 I 0.810
bcl11ab Gasterosteus aculeatus ENSGACG00000019222 I 0.810
ENSPFOG00000007302 Poecilia formosa ENSPFOG00000007302 I 0.807
bcl11ab Tetraodon nigroviridis ENSTNIG00000012076 I 0.807
bcl11aa Danio rerio ENSDARG00000061352 I 0.807
bcl11ab Danio rerio ENSDARG00000063153 I 0.807
bcl11ab Takifugu rubripes ENSTRUG00000013751 I 0.807
bcl11ab Oryzias latipes ENSORLG00000013169 I 0.807
ENSONIG00000018855 Oreochromis niloticus ENSONIG00000018855 I 0.807
ENSOCUG00000024296 Oryctolagus cuniculus ENSOCUG00000024296 I 0.807
im:7142702 Tetraodon nigroviridis ENSTNIG00000009693 I 0.804
ENSP00000338774 Macaca fascicularis ENSP00000338774 I 0.802
Afo_R011357 Aptenodytes forsteri Afo_R011357 I 0.802
Alligator_sinensis_CCG008166.1 Alligator sinensis Alligator_sinensis_CCG008166.1 I 0.802
Cmyd_10008592 Chelonia mydas Cmyd_10008592 I 0.802
BCL11A Taeniopygia guttata ENSTGUG00000006790 I 0.802
ENSAPLG00000007735 Anas platyrhynchos ENSAPLG00000007735 I 0.802
ENSAMEG00000015813 Ailuropoda melanoleuca ENSAMEG00000015813 I 0.802
Aan_R006276 Calypte anna Aan_R006276 I 0.802
BCL11A Anolis carolinensis ENSACAG00000015159 I 0.802
Pvit_18645 Pogona vitticeps Pvit_18645 I 0.802
BCL11A Callithrix jacchus ENSCJAG00000009226 I 0.802
ENSBTAP00000023987-D2 Bos grunniens ENSBTAP00000023987-D2 I 0.802
bcl11a Xenopus tropicalis XB-GENE-486641 I 0.802
Gfo_R008167 Geospiza fortis Gfo_R008167 I 0.802
ENSTSYG00000009153 Tarsius syrichta ENSTSYG00000009153 I 0.802
BCL11A Tursiops truncatus ENSTTRG00000006191 I 0.802
BCL11A Vicugna pacos ENSVPAG00000000491 I 0.802
BCL11A Cavia porcellus ENSCPOG00000007587 I 0.802
BCL11A Loxodonta africana ENSLAFG00000003101 I 0.802
ENSGALG00000007866 Gallus gallus ENSGALG00000007866 I 0.802
BCL11A Meleagris gallopavo ENSMGAG00000013042 I 0.802
BCL11A Ornithorhynchus anatinus ENSOANG00000012402 I 0.802
Bcl11a Mus musculus ENSMUSG00000000861 I 0.802
ENSMEUG00000001829 Macropus eugenii ENSMEUG00000001829 I 0.802
BCL11A Homo sapiens ENSG00000119866 D 0.802
BCL11A Oryctolagus cuniculus ENSOCUG00000023948 I 0.802
BCL11A Felis catus ENSFCAG00000027154 I 0.802
ENSSTOG00000004523 Ictidomys tridecemlineatus ENSSTOG00000004523 I 0.802
ENSFALG00000011123 Ficedula albicollis ENSFALG00000011123 I 0.802
ENSLACG00000003560 Latimeria chalumnae ENSLACG00000003560 I 0.802
Bcl11a Rattus norvegicus ENSRNOG00000007049 I 0.802
BCL11A Pteropus vampyrus ENSPVAG00000000042 I 0.802
ENSSHAG00000015804 Sarcophilus harrisii ENSSHAG00000015804 I 0.802
BCL11A Gorilla gorilla ENSGGOG00000007337 I 0.802
BCL11A Sus scrofa ENSSSCG00000008392 I 0.802
ENSMMUG00000011303 Macaca mulatta ENSMMUG00000011303 I 0.802
BCL11A Dasypus novemcinctus ENSDNOG00000019842 I 0.802
BCL11A Microcebus murinus ENSMICG00000015052 I 0.802
BCL11A Erinaceus europaeus ENSEEUG00000010958 I 0.802
Bcl11a Dipodomys ordii ENSDORG00000010064 I 0.802
ENSPSIG00000013644 Pelodiscus sinensis ENSPSIG00000013644 I 0.802
ENSAMXG00000004597 Astyanax mexicanus ENSAMXG00000004597 I 0.800
SMAR003355 Strigamia maritima SMAR003355 I 0.799
ENSXMAG00000007242 Xiphophorus maculatus ENSXMAG00000007242 I 0.798
SPU_018909 Strongylocentrotus purpuratus SPU_018909 I 0.797
bcl11aa Gasterosteus aculeatus ENSGACG00000013419 I 0.796
ENSONIG00000002906 Oreochromis niloticus ENSONIG00000002906 I 0.796
bcl11aa Takifugu rubripes ENSTRUG00000003815 I 0.796
ENSPFOG00000019062 Poecilia formosa ENSPFOG00000019062 I 0.796
bcl11aa Oryzias latipes ENSORLG00000001704 I 0.796
Ocbimv22018271m.g Octopus bimaculoides Ocbimv22018271m.g I 0.796
ISCW016418 Ixodes scapularis ISCW016418 I 0.787
PHUM606430 Pediculus humanus PHUM606430 I 0.783
RPRC001562 Rhodnius prolixus RPRC001562 I 0.778
LotgiG139415 Lottia gigantea LotgiG139415 I 0.773
L798_02171 Zootermopsis nevadensis L798_02171 I 0.773
HHAL008065-PA Halyomorpha halys HHAL008065-PA I 0.772
ACYPI007319 Acyrthosiphon pisum ACYPI007319 I 0.759
CapteG65449 Capitella teleta CapteG65449 I 0.758
BGLB012676 Biomphalaria glabrata BGLB012676 I 0.758
AMEC015245 Anopheles melas AMEC015245 I 0.756