ENSP00000353734 (Macaca fascicularis)
C2H2 ZF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source
PF00096 (zf-C2H2) IPR007087 ENSP00000353734 T135266_2.00 GigaDB (2015-Oct-22)
NCBI Gene Info:
This gene encodes a C2H2 zinc finger protein that functions as a suppressor of cell growth. This gene is often deleted or methylated and silenced in cancer cells. In addition, overexpression of this gene during fetal development is thought to be the causal factor for transient neonatal diabetes mellitus (TNDM). Alternative splicing and the use of alternative promoters results in multiple transcript variants encoding two different protein isoforms. The P1 downstream promoter of this gene is imprinted, with preferential expression from the paternal allele in many tissues. [provided by RefSeq, Nov 2015]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
Plagl1
M00130_2.00
Mus musculus
NNNVCCCCHN

NDGGGGBNNN
PBM
Badis et al.(2009)
Plagl1_0972
0.790 0.884
For this family, TFs with SR scores > 0.755 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000353734 C2H2 ZF 4 26
ENSP00000353734 C2H2 ZF 32 56
ENSP00000353734 C2H2 ZF 62 84
ENSP00000353734 C2H2 ZF 91 113
ENSP00000353734 C2H2 ZF 156 178
ENSP00000353734 C2H2 ZF 184 207

Links

Other C2H2 ZF family TFs
Other Macaca fascicularis TFs

26 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action
ENSPPYG00000017067 Pongo abelii ENSPPYG00000017067 I 0.827
PLAGL1 Macaca mulatta ENSMMUG00000003750 I 0.827
PLAGL1 Gorilla gorilla ENSGGOG00000016889 I 0.827
PLAGL1 Homo sapiens ENSG00000118495 I 0.827
ENSCSAG00000017096 Chlorocebus sabaeus ENSCSAG00000017096 I 0.827
PLAGL1 Pan troglodytes ENSPTRG00000018675 I 0.827
PLAGL1 Tursiops truncatus ENSTTRG00000008814 I 0.825
ENSAMEG00000011495 Ailuropoda melanoleuca ENSAMEG00000011495 I 0.825
PLAGL1 Sus scrofa ENSSSCG00000004127 I 0.825
ENSMPUG00000018050 Mustela putorius furo ENSMPUG00000018050 I 0.825
PLAGL1 Felis catus ENSFCAG00000008565 I 0.825
PLAGL1 Canis familiaris ENSCAFG00000000318 I 0.825
PLAGL1 Sorex araneus ENSSARG00000007774 I 0.823
ENSNLEG00000015144 Nomascus leucogenys ENSNLEG00000015144 I 0.817
ENSPANG00000019615 Papio anubis ENSPANG00000019615 I 0.817
PLAGL1 Erinaceus europaeus ENSEEUG00000000604 I 0.816
ENSP00000388045-D1 Bos grunniens ENSP00000388045-D1 I 0.815
ENSOARG00000001749 Ovis aries ENSOARG00000001749 I 0.814
PLAGL1 Equus caballus ENSECAG00000000641 I 0.813
PLAGL1 Cavia porcellus ENSCPOG00000021814 I 0.809
PLAGL1 Echinops telfairi ENSETEG00000004193 I 0.806
PLAGL1 Callithrix jacchus ENSCJAG00000019308 I 0.802
Plagl1 Rattus norvegicus ENSRNOG00000025587 I 0.792
PLAGL1 Otolemur garnettii ENSOGAG00000012149 I 0.792
ENSSTOG00000012909 Ictidomys tridecemlineatus ENSSTOG00000012909 I 0.791
Plagl1 Mus musculus ENSMUSG00000019817 D 0.790