ENSP00000369270 (Macaca fascicularis)
C2H2 ZF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source
PF00096 (zf-C2H2) IPR007087 ENSP00000369270 T135358_2.00 GigaDB (2015-Oct-22)
NCBI Gene Info:
The protein encoded by this gene is a zinc finger transcription factor that binds to RAS-responsive elements (RREs) of gene promoters. It has been shown that the calcitonin gene promoter contains an RRE and that the encoded protein binds there and increases expression of calcitonin, which may be involved in Ras/Raf-mediated cell differentiation. Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Dec 2009]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
RREB1
M02665_2.00
Homo sapiens
MCMCMAMMCAMCMMCHMMSV

BSKKDGKKGKTGKKTKGKGK
SELEX
Mathelier et al.(2014)
MA0073.1
0.827 1.000
RREB1
M10203_2.00
Homo sapiens
MCCCAAMCMMMCMM

KKGKKKGKTTGGGK
Transfac
Matys et al.(2006)
V$RREB1_01
0.827 1.000
RREB1
M10204_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$RREB1_Q5
0.827 1.000
RREB1
M10205_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$RREB_Q5
0.827 1.000
For this family, TFs with SR scores > 0.755 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000369270 C2H2 ZF 66 88
ENSP00000369270 C2H2 ZF 97 119
ENSP00000369270 C2H2 ZF 125 147
ENSP00000369270 C2H2 ZF 620 642
ENSP00000369270 C2H2 ZF 648 670
ENSP00000369270 C2H2 ZF 676 699
ENSP00000369270 C2H2 ZF 730 752
ENSP00000369270 C2H2 ZF 767 790
ENSP00000369270 C2H2 ZF 1223 1245
ENSP00000369270 C2H2 ZF 1251 1274
ENSP00000369270 C2H2 ZF 1513 1535
ENSP00000369270 C2H2 ZF 1541 1563

Links

Other C2H2 ZF family TFs
Other Macaca fascicularis TFs

20 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action
ENSNLEG00000011554 Nomascus leucogenys ENSNLEG00000011554 I 0.827
ENSPANG00000019553 Papio anubis ENSPANG00000019553 I 0.827
ENSPPYG00000016204 Pongo abelii ENSPPYG00000016204 I 0.827
RREB1 Pan troglodytes ENSPTRG00000017697 I 0.827
RREB1 Gorilla gorilla ENSGGOG00000004561 I 0.827
RREB1 Macaca mulatta ENSMMUG00000007852 I 0.827
ENSCSAG00000007376 Chlorocebus sabaeus ENSCSAG00000007376 I 0.827
RREB1 Homo sapiens ENSG00000124782 D 0.827
ENSAMEG00000017412 Ailuropoda melanoleuca ENSAMEG00000017412 I 0.826
Rreb1 Rattus norvegicus ENSRNOG00000015701 I 0.823
RREB1 Canis familiaris ENSCAFG00000009527 I 0.822
Rreb1 Mus musculus ENSMUSG00000039087 I 0.819
RREB1 Loxodonta africana ENSLAFG00000005300 I 0.818
ENSMPUG00000000558 Mustela putorius furo ENSMPUG00000000558 I 0.818
RREB1 Monodelphis domestica ENSMODG00000009892 I 0.813
ENSMEUG00000015377 Macropus eugenii ENSMEUG00000015377 I 0.813
RREB1 Felis catus ENSFCAG00000030069 I 0.810
RREB1 Pteropus vampyrus ENSPVAG00000014081 I 0.809
Cmyd_10003405 Chelonia mydas Cmyd_10003405 I 0.803
RREB1 Anolis carolinensis ENSACAG00000000520 I 0.787