ENSP00000409872 (Macaca fascicularis)
C2H2 ZF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source
PF00096 (zf-C2H2) IPR007087 ENSP00000409872 T135571_2.00 GigaDB (2015-Oct-22)
NCBI Gene Info:
This gene encodes a zinc finger protein containing five C2H2-type zinc finger domains, one or two Kruppel-associated box A (KRAB A) domains, and a leucine-rich domain. The encoded protein has been suggested to be a transcriptional repressor. It localizes predominantly to the nucleolus. Alternatively spliced transcript variants encoding different isoforms exist. These variants utilize alternative polyadenylation signals. [provided by RefSeq, Jul 2008]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
ZNF274
M04549_2.00
Homo sapiens
NVYGAGRACTCAYRYN

NRYRTGAGTYCTCRBN
SELEX
Yin et al.(2017)
ZNF274_eDBD_HT-SELEX
0.823 0.983
ZNF274
M07632_2.00
Homo sapiens
CWGTRTGARTTCTCW

WGAGAAYTCAYACWG
ChIP-seq+ChIP-exo
Barazandeh et al.(2018)
ZNF274.RCADE.ReprocessedData
0.823 0.983
ZNF274
M07933_2.00
Homo sapiens
YTTCTCHCCAGTRTGAR

YTCAYACTGGDGAGAAR
ChIP-seq
Gerstein et al.(2012)
HeLa-S3_ZNF274_UCD
0.823 0.983
ZNF274
M07934_2.00
Homo sapiens
GGTTTYTCTCCAGTR

YACTGGAGARAAACC
ChIP-seq
Gerstein et al.(2012)
HepG2b_ZNF274_UCD
0.823 0.983
ZNF274
M07935_2.00
Homo sapiens
GAGAAYTCAYACTGG

CCAGTRTGARTTCTC
ChIP-seq
Gerstein et al.(2012)
K562b_ZNF274_UCD
0.823 0.983
ZNF274
M07936_2.00
Homo sapiens
TTYTCTCCAGTRTGA

TCAYACTGGAGARAA
ChIP-seq
Gerstein et al.(2012)
NT2-D1_ZNF274_UCD
0.823 0.983
ZNF274
M08916_2.00
Homo sapiens
TWNGRTTTCTYTCCAKTRTG

CAYAMTGGARAGAAAYCNWA
Misc
Kulakovskiy et al.(2013)
ZN274_HUMAN.H11MO.0.A
0.823 0.983
ZNF274
M04550_2.00
Homo sapiens
NVHGAGRACTCAYRYN

NRYRTGAGTYCTCDBN
SELEX
Yin et al.(2017)
ZNF274_eDBD_Methyl-HT-SELEX
0.823 0.983
For this family, TFs with SR scores > 0.755 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000409872 C2H2 ZF 569 591
ENSP00000409872 C2H2 ZF 597 619
ENSP00000409872 C2H2 ZF 625 647
ENSP00000409872 C2H2 ZF 653 675
ENSP00000409872 C2H2 ZF 681 703

Links

Other C2H2 ZF family TFs
Other Macaca fascicularis TFs

26 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action
ZNF274 Macaca mulatta ENSMMUG00000020505 I 0.827
ENSPANG00000012245 Papio anubis ENSPANG00000012245 I 0.825
ENSCSAG00000019664 Chlorocebus sabaeus ENSCSAG00000019664 I 0.825
ZNF274 Pan troglodytes ENSPTRG00000011583 I 0.823
ZNF274 Gorilla gorilla ENSGGOG00000004688 I 0.823
ENSPPYG00000010493 Pongo abelii ENSPPYG00000010493 I 0.823
ENSNLEG00000011103 Nomascus leucogenys ENSNLEG00000011103 I 0.823
ZNF274 Homo sapiens ENSG00000171606 D 0.823
ZNF544 Callithrix jacchus ENSCJAG00000000329 I 0.823
ZNF274 Tursiops truncatus ENSTTRG00000013077 I 0.800
ENSTSYG00000010913 Tarsius syrichta ENSTSYG00000010913 I 0.799
ZNF274 Microcebus murinus ENSMICG00000017855 I 0.798
ZNF274 Otolemur garnettii ENSOGAG00000005637 I 0.798
ZNF274 Equus caballus ENSECAG00000007526 I 0.797
ENSMPUG00000008378 Mustela putorius furo ENSMPUG00000008378 I 0.796
ZNF274 Sus scrofa ENSSSCG00000003998 I 0.795
ZNF274 Dasypus novemcinctus ENSDNOG00000032910 I 0.792
ZNF274 Sorex araneus ENSSARG00000001423 I 0.788
ZNF274 Tupaia belangeri ENSTBEG00000006394 I 0.788
ZNF274 Pteropus vampyrus ENSPVAG00000002938 I 0.781
ZNF274 Ochotona princeps ENSOPRG00000007383 I 0.781
ZNF274 Erinaceus europaeus ENSEEUG00000008228 I 0.779
ZNF274 Bos taurus ENSBTAG00000013353 I 0.778
Myotis_brandtii_ZNF274_10003422 Myotis brandtii Myotis_brandtii_ZNF274_10003422 I 0.771
Zfp110 Rattus norvegicus ENSRNOG00000031328 I 0.760
Zfp110 Mus musculus ENSMUSG00000058638 I 0.760