ENSP00000417899-D1 (Bos grunniens)
C2H2 ZF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source
PF00096 (zf-C2H2) IPR007087 ENSP00000417899-D1 T135611_2.00 GigaDB (2015-Oct-22)
NCBI Gene Info:
The protein encoded by this gene is a transcriptional regulator and oncoprotein that may be involved in hematopoiesis, apoptosis, development, and cell differentiation and proliferation. The encoded protein can interact with CTBP1, SMAD3, CREBBP, KAT2B, MAPK8, and MAPK9. This gene can undergo translocation with the AML1 gene, resulting in overexpression of this gene and the onset of leukemia. Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq, Mar 2011]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
MECOM
M08862_2.00
Homo sapiens
HNTNTTATCTTRTCWN

NWGAYAAGATAANAND
Misc
Kulakovskiy et al.(2013)
EVI1_HUMAN.H11MO.0.B
0.827 0.996
MECOM
M10125_2.00
Homo sapiens
TTATCTTATCTTRTCW

WGAYAAGATAAGATAA
Transfac
Matys et al.(2006)
V$EVI1_01
0.827 0.996
MECOM
M10126_2.00
Homo sapiens
TTATCTTRTCH

DGAYAAGATAA
Transfac
Matys et al.(2006)
V$EVI1_02
0.827 0.996
MECOM
M10127_2.00
Homo sapiens
TTATCTTATCT

AGATAAGATAA
Transfac
Matys et al.(2006)
V$EVI1_03
0.827 0.996
MECOM
M10128_2.00
Homo sapiens
TAWYYWDWYHTATYH

DRATADRAHWRRAWA
Transfac
Matys et al.(2006)
V$EVI1_04
0.827 0.996
MECOM
M10129_2.00
Homo sapiens
HTATCTTATCT

AGATAAGATAD
Transfac
Matys et al.(2006)
V$EVI1_05
0.827 0.996
MECOM
M10130_2.00
Homo sapiens
TTATCTTGT

ACAAGATAA
Transfac
Matys et al.(2006)
V$EVI1_06
0.827 0.996
MECOM
M10131_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$EVI1_Q3
0.827 0.996
MECOM
M10132_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$EVI_Q6
0.827 0.996
Mecom
M02667_2.00
Mus musculus
KNTTATCTTRTCTH

DAGAYAAGATAANM
SELEX
Mathelier et al.(2014)
MA0029.1
0.822 0.982
Mecom
M08980_2.00
Mus musculus
HNTNTTATCTTRTCWN

NWGAYAAGATAANAND
Misc
Kulakovskiy et al.(2013)
EVI1_MOUSE.H11MO.0.B
0.822 0.982
For this family, TFs with SR scores > 0.755 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000417899-D1 C2H2 ZF 200 221
ENSP00000417899-D1 C2H2 ZF 254 276
ENSP00000417899-D1 C2H2 ZF 282 304
ENSP00000417899-D1 C2H2 ZF 310 333
ENSP00000417899-D1 C2H2 ZF 339 361
ENSP00000417899-D1 C2H2 ZF 367 389
ENSP00000417899-D1 C2H2 ZF 396 417
ENSP00000417899-D1 C2H2 ZF 903 925
ENSP00000417899-D1 C2H2 ZF 931 954
ENSP00000417899-D1 C2H2 ZF 960 982

Links

Other C2H2 ZF family TFs
Other Bos grunniens TFs

Invalid Input OrderBy

52 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action