HHAL001092-PA (Halyomorpha halys)
C2H2 ZF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source
PF00096 (zf-C2H2) IPR007087 HHAL001092-PA T144002_2.00 Misc (2018-Jan-19)
NCBI Gene Info:
This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277). [provided by RefSeq, Dec 2016]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
scrt
M03673_2.00
Drosophila melanogaster
RHGCAACAGGTGK

MCACCTGTTGCDY
SELEX
Nitta et al.(2015)
scrt_1
0.804 0.956
scrt
M06085_2.00
Drosophila melanogaster
MCCACCTGTTG

CAACAGGTGGK
B1H
Zhu et al.(2011)
scrt_SANGER_2.5_FBgn0004880
0.804 0.956
scrt
M06086_2.00
Drosophila melanogaster
DNKCAACAGGTGK

MCACCTGTTGMNH
B1H
Zhu et al.(2011)
scrt_SOLEXA_2.5_1_FBgn0004880
0.804 0.956
scrt
M06087_2.00
Drosophila melanogaster
VMCACCTGTTGMN

NKCAACAGGTGKB
B1H
Zhu et al.(2011)
scrt_SOLEXA_2.5_2_FBgn0004880
0.804 0.956
SCRT1
M02929_2.00
Homo sapiens
RHKCAACAGGTGKNH

DNMCACCTGTTGMDY
SELEX
Jolma et al.(2013)
SCRT1_1
0.792 0.842
SCRT1
M04655_2.00
Homo sapiens
NKCAACAGGTD

HACCTGTTGMN
SELEX
Yin et al.(2017)
SCRT1_eDBD_HT-SELEX
0.792 0.842
SCRT1
M08397_2.00
Homo sapiens
RWKCAACAGGTG

CACCTGTTGMWY
ChIP-seq
Schmitges et al.(2016)
Q9BWW7_1-4.RCADE
0.792 0.842
SCRT1
M04656_2.00
Homo sapiens
NGCRACAGGTD

HACCTGTYGCN
SELEX
Yin et al.(2017)
SCRT1_eDBD_Methyl-HT-SELEX
0.792 0.842
CG12605
M03691_2.00
Drosophila melanogaster
RHGCAACAGGTGN

NCACCTGTTGCDY
SELEX
Nitta et al.(2015)
CG12605_1
0.776 0.895
CG12605
M06139_2.00
Drosophila melanogaster
CACCTGTKG

CMACAGGTG
B1H
Zhu et al.(2011)
CG12605_SANGER_10_FBgn0035481
0.776 0.895
CG12605
M06140_2.00
Drosophila melanogaster
MCACCTGTKGVNN

NNBCMACAGGTGK
B1H
Zhu et al.(2011)
CG12605_SOLEXA_5_FBgn0035481
0.776 0.895
SCRT2
M02925_2.00
Homo sapiens
RHGCAACAGGTGB

VCACCTGTTGCDY
SELEX
Jolma et al.(2013)
SCRT2_1
0.774 0.833
SCRT2
M04643_2.00
Homo sapiens
NGCAACAGGTD

HACCTGTTGCN
SELEX
Yin et al.(2017)
SCRT2_eDBD_HT-SELEX
0.774 0.833
SCRT2
M04644_2.00
Homo sapiens
NGCRACAGGTG

CACCTGTYGCN
SELEX
Yin et al.(2017)
SCRT2_eDBD_Methyl-HT-SELEX
0.774 0.833
For this family, TFs with SR scores > 0.755 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
HHAL001092-PA C2H2 ZF 197 219
HHAL001092-PA C2H2 ZF 228 250
HHAL001092-PA C2H2 ZF 254 276
HHAL001092-PA C2H2 ZF 282 304
HHAL001092-PA C2H2 ZF 310 331

Links

Other C2H2 ZF family TFs
Other Halyomorpha halys TFs

196 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action
CLEC001353 Cimex lectularius CLEC001353 I 0.823
HHAL001095-PA Halyomorpha halys HHAL001095-PA I 0.818
L798_11766 Zootermopsis nevadensis L798_11766 I 0.816
ACUA022497 Anopheles culicifacies ACUA022497 I 0.811
AFAF007486 Anopheles farauti AFAF007486 I 0.811
ACOM031685 Anopheles coluzzii ACOM031685 I 0.811
ACHR010032 Anopheles christyi ACHR010032 I 0.811
CPIJ017517 Culex quinquefasciatus CPIJ017517 I 0.811
AFUN002786 Anopheles funestus AFUN002786 I 0.811
AATE020159 Anopheles atroparvus AATE020159 I 0.811
AAEL005176 Aedes aegypti AAEL005176 I 0.811
AMEC013076 Anopheles melas AMEC013076 I 0.811
ASIS022059 Anopheles sinensis ASIS022059 I 0.811
CpipJ_CPIJ017517 Culex pipiens CpipJ_CPIJ017517 I 0.811
AGAP006791 Anopheles gambiae AGAP006791 I 0.811
AQUA003879 Anopheles quadriannulatus AQUA003879 I 0.811
AMEM013788 Anopheles merus AMEM013788 I 0.811
GM11368 Drosophila sechellia FBgn0166311 I 0.804
GM14603 Drosophila sechellia FBgn0169524 I 0.804
GI12551 Drosophila mojavensis FBgn0135308 I 0.804
GF25020 Drosophila ananassae FBgn0102012 I 0.804
GD13794 Drosophila simulans FBgn0185494 I 0.804
GH15771 Drosophila grimshawi FBgn0123242 I 0.804
GK17507 Drosophila willistoni FBgn0219506 I 0.804
LCUP005780 Lucilia cuprina LCUP005780 I 0.804
MDOA005810 Musca domestica MDOA005810 I 0.804
GE21392 Drosophila yakuba FBgn0238652 I 0.804
scrt Drosophila melanogaster FBgn0004880 D 0.804
GJ16103 Drosophila virilis FBgn0203288 I 0.804
GG15174 Drosophila erecta FBgn0107427 I 0.804
LLOJ003272 Lutzomyia longipalpis LLOJ003272 I 0.802
SCRT1 Gasterosteus aculeatus ENSGACG00000004072 I 0.802
ENSPFOG00000005616 Poecilia formosa ENSPFOG00000005616 I 0.802
ENSONIG00000019809 Oreochromis niloticus ENSONIG00000019809 I 0.802
ENSXMAG00000015353 Xiphophorus maculatus ENSXMAG00000015353 I 0.802
SCRT1 Takifugu rubripes ENSTRUG00000012719 I 0.802
PHUM474180 Pediculus humanus PHUM474180 I 0.802
tetur08g05890 Tetranychus urticae tetur08g05890 I 0.802
ENSPFOG00000017719 Poecilia formosa ENSPFOG00000017719 I 0.800
ISCW021315 Ixodes scapularis ISCW021315 I 0.800
ENSONIG00000006007 Oreochromis niloticus ENSONIG00000006007 I 0.800
ENSAMXG00000004776 Astyanax mexicanus ENSAMXG00000004776 I 0.800
scrt1b Tetraodon nigroviridis ENSTNIG00000018384 I 0.800
ENSXMAG00000014491 Xiphophorus maculatus ENSXMAG00000014491 I 0.800
ENSGMOG00000000629 Gadus morhua ENSGMOG00000000629 I 0.800
SMAR010760 Strigamia maritima SMAR010760 I 0.800
scrt1b Takifugu rubripes ENSTRUG00000011637 I 0.800
scrt1b Oryzias latipes ENSORLG00000008641 I 0.800
ACYPI004643 Acyrthosiphon pisum ACYPI004643 I 0.799
Cflo_09305--XP_001121064.1_APIME Camponotus floridanus Cflo_09305--XP_001121064.1_APIME I 0.799
ENSLOCG00000007573 Lepisosteus oculatus ENSLOCG00000007573 I 0.797
scrt1b Gasterosteus aculeatus ENSGACG00000008982 I 0.797
scrt1a Danio rerio ENSDARG00000100821 I 0.797
scrt1b Danio rerio ENSDARG00000040214 I 0.797
ENSLACG00000003588 Latimeria chalumnae ENSLACG00000003588 I 0.797
ENSAPLG00000011730 Anas platyrhynchos ENSAPLG00000011730 I 0.795
ACUA003488 Anopheles culicifacies ACUA003488 I 0.794
ACUA020861 Anopheles culicifacies ACUA020861 I 0.794
AFUN001835 Anopheles funestus AFUN001835 I 0.794
ASTEI08595 Anopheles stephensi ASTEI08595 I 0.794
SCRT1 Homo sapiens ENSG00000261678 D 0.792
ENSSTOG00000023184 Ictidomys tridecemlineatus ENSSTOG00000023184 I 0.792
ENSSHAG00000001992 Sarcophilus harrisii ENSSHAG00000001992 I 0.792
Scrt1 Rattus norvegicus ENSRNOG00000025594 I 0.792
SCRT1 Dasypus novemcinctus ENSDNOG00000043826 I 0.792
ENSAMEG00000005557 Ailuropoda melanoleuca ENSAMEG00000005557 I 0.792
HMEL014701 Heliconius melpomene HMEL014701 I 0.792
PPAI000594 Phlebotomus papatasi PPAI000594 I 0.792
MCINX009925 Melitaea cinxia MCINX009925 I 0.792
SCRT1 Bos taurus ENSBTAG00000046208 I 0.792
ENSCSAG00000008549 Chlorocebus sabaeus ENSCSAG00000008549 I 0.792
KGM_21493 Danaus plexippus KGM_21493 I 0.792
SCRT1 Callithrix jacchus ENSCJAG00000021406 I 0.792
SCRT1 Sus scrofa ENSSSCG00000025879 I 0.792
Scrt1 Mus musculus ENSMUSG00000048385 I 0.792
SCRT1 Gorilla gorilla ENSGGOG00000013612 I 0.792
SCRT1 Macaca mulatta ENSMMUG00000028886 I 0.792
AATE010651 Anopheles atroparvus AATE010651 I 0.792
ACOM031677 Anopheles coluzzii ACOM031677 I 0.792
SCRT1 Otolemur garnettii ENSOGAG00000026538 I 0.792
ENSOARG00000014008 Ovis aries ENSOARG00000014008 I 0.792
AFAF017001 Anopheles farauti AFAF017001 I 0.792
BGIBMGA000607 Bombyx mori BGIBMGA000607 I 0.792
ENSPANG00000017232 Papio anubis ENSPANG00000017232 I 0.792
AMEC015586 Anopheles melas AMEC015586 I 0.792
AMEM017035 Anopheles merus AMEM017035 I 0.792
SCRT1 Loxodonta africana ENSLAFG00000031587 I 0.792
ENSCPOG00000024058 Cavia porcellus ENSCPOG00000024058 I 0.792
ASIS012063 Anopheles sinensis ASIS012063 I 0.792
AGAP006794 Anopheles gambiae AGAP006794 I 0.792
CpipJ_CPIJ004535 Culex pipiens CpipJ_CPIJ004535 I 0.790
ENSAMXG00000018733 Astyanax mexicanus ENSAMXG00000018733 I 0.790
scrt2 Danio rerio ENSDARG00000056175 I 0.790
CapteG223614 Capitella teleta CapteG223614 I 0.790
Ocbimv22039583m.g Octopus bimaculoides Ocbimv22039583m.g I 0.790
scrt2 Tetraodon nigroviridis ENSTNIG00000012473 I 0.790
ENSONIG00000016758 Oreochromis niloticus ENSONIG00000016758 I 0.790
scrt2 Oryzias latipes ENSORLG00000015072 I 0.790
scrt2 Xenopus tropicalis XB-GENE-5995512 I 0.790
AAEL014359 Aedes aegypti AAEL014359 I 0.790
scrt2 Takifugu rubripes ENSTRUG00000007620 I 0.790
CPIJ004535 Culex quinquefasciatus CPIJ004535 I 0.790
Ogr05737 Ophisaurus gracilis Ogr05737 I 0.790
ENSPFOG00000007738 Poecilia formosa ENSPFOG00000007738 I 0.790
AAEL009230 Aedes aegypti AAEL009230 I 0.790
ENSXMAG00000011590 Xiphophorus maculatus ENSXMAG00000011590 I 0.790
Sakowv30035375m.g Saccoglossus kowalevskii Sakowv30035375m.g I 0.788
SPU_018393 Strongylocentrotus purpuratus SPU_018393 I 0.788
Cmyd_10009565 Chelonia mydas Cmyd_10009565 I 0.788
ENSFALG00000005718 Ficedula albicollis ENSFALG00000005718 I 0.788
CGI_10023711 Crassostrea gigas CGI_10023711 I 0.787
SCRT2 Anolis carolinensis ENSACAG00000016109 I 0.786
SCRT2 Gallus gallus ENSGALG00000028912 I 0.786
SCRT2 Taeniopygia guttata ENSTGUG00000006801 I 0.786
SCRT2 Meleagris gallopavo ENSMGAG00000016579 I 0.786
ENSONIG00000003152 Oreochromis niloticus ENSONIG00000003152 I 0.783
CapteG149623 Capitella teleta CapteG149623 I 0.782
ENSGMOG00000019519 Gadus morhua ENSGMOG00000019519 I 0.781
ENSAMXG00000018604 Astyanax mexicanus ENSAMXG00000018604 I 0.781
scrt2 Gasterosteus aculeatus ENSGACG00000011802 I 0.781
SCRT2 Monodelphis domestica ENSMODG00000019528 I 0.780
D917_06340 Trichinella nativa D917_06340 I 0.780
Pvit_17685 Pogona vitticeps Pvit_17685 I 0.780
EFV52761 Trichinella spiralis EFV52761 I 0.780
ENSMEUG00000009675 Macropus eugenii ENSMEUG00000009675 I 0.780
estExt_fgenesh2_pm.C_2290002 Branchiostoma floridae estExt_fgenesh2_pm.C_2290002 I 0.780
GA11715 Drosophila pseudoobscura FBgn0071765 I 0.778
GK16692 Drosophila willistoni FBgn0218694 I 0.778
ENSLOCG00000002246 Lepisosteus oculatus ENSLOCG00000002246 I 0.776
CG12605 Drosophila melanogaster FBgn0035481 D 0.776
GE20660 Drosophila yakuba FBgn0237965 I 0.776
GI12763 Drosophila mojavensis FBgn0135520 I 0.776
GD13305 Drosophila simulans FBgn0185024 I 0.776
GJ16104 Drosophila virilis FBgn0203289 I 0.776
GD13304 Drosophila simulans FBgn0185023 I 0.776
GG14232 Drosophila erecta FBgn0106493 I 0.776
GM14024 Drosophila sechellia FBgn0168953 I 0.776
GF24781 Drosophila ananassae FBgn0101774 I 0.776
ACYPI34938 Acyrthosiphon pisum ACYPI34938 I 0.775
PHUM474050 Pediculus humanus PHUM474050 I 0.775
ENSGGOG00000015228 Gorilla gorilla ENSGGOG00000015228 I 0.774
TTRE_0000441701 Trichuris trichiura TTRE_0000441701 I 0.774
SCRT2 Loxodonta africana ENSLAFG00000030340 I 0.774
SCRT2 Homo sapiens ENSG00000215397 D 0.774
D918_03987 Trichuris suis D918_03987 I 0.774
TMUE_s0027002700 Trichuris muris TMUE_s0027002700 I 0.774
ENSCSAG00000010473 Chlorocebus sabaeus ENSCSAG00000010473 I 0.774
SCRT2 Dasypus novemcinctus ENSDNOG00000002583 I 0.774
MDOA001622 Musca domestica MDOA001622 I 0.774
ENSMMUG00000017354 Macaca mulatta ENSMMUG00000017354 I 0.774
SCRT2 Felis catus ENSFCAG00000010922 I 0.774
SCRT2 Otolemur garnettii ENSOGAG00000031187 I 0.774
LCUP005777 Lucilia cuprina LCUP005777 I 0.774
SCRT2 Callithrix jacchus ENSCJAG00000020870 I 0.774
ENSNLEG00000009420 Nomascus leucogenys ENSNLEG00000009420 I 0.774
SCRT2 Tursiops truncatus ENSTTRG00000007039 I 0.774
Scrt2 Mus musculus ENSMUSG00000060257 I 0.774
SCRT2 Cavia porcellus ENSCPOG00000008447 I 0.774
Scrt2 Rattus norvegicus ENSRNOG00000005148 I 0.774
SMU15013927 Schmidtea mediterranea SMU15013927 I 0.773
CapteG176021 Capitella teleta CapteG176021 I 0.772
CapteG76620 Capitella teleta CapteG76620 I 0.772
LotgiG58520 Lottia gigantea LotgiG58520 I 0.771
ECPE_0000958201 Echinostoma caproni ECPE_0000958201 I 0.771
MESCA005876 Megaselia scalaris MESCA005876 I 0.771
D915_06717 Fasciola hepatica D915_06717 I 0.771
DAPPUDRAFT_14328 Daphnia pulex DAPPUDRAFT_14328 I 0.770
TriadG20314 Trichoplax adhaerens TriadG20314 I 0.769
SMRZ_0000904801 Schistosoma margrebowiei SMRZ_0000904801 I 0.768
SCUD_0000371801 Schistosoma curassoni SCUD_0000371801 I 0.768
L893_g27175 Steinernema glaseri L893_g27175 I 0.768
T265_09545 Opisthorchis viverrini T265_09545 I 0.768
csin111588 Clonorchis sinensis csin111588 I 0.768
Smp_054430 Schistosoma mansoni Smp_054430 I 0.768
Sjc_0100840 Schistosoma japonicum Sjc_0100840 I 0.768
TRE_0000944501 Trichobilharzia regenti TRE_0000944501 I 0.768
A_07725 Schistosoma haematobium A_07725 I 0.768
SMTD_0000188801 Schistosoma mattheei SMTD_0000188801 I 0.768
PXEA_0002510801 Protopolystoma xenopodis PXEA_0002510801 I 0.766
PTRK_0000719800 Parastrongyloides trichosuri PTRK_0000719800 I 0.766
SVE_1799900 Strongyloides venezuelensis SVE_1799900 I 0.766
SSTP_0000144900 Strongyloides stercoralis SSTP_0000144900 I 0.766
SPAL_0000842500 Strongyloides papillosus SPAL_0000842500 I 0.766
nRc.2.0.1.g22231 Romanomermis culicivorax nRc.2.0.1.g22231 I 0.765
RSKR_0000492900 Rhabditophanes kr3021 RSKR_0000492900 I 0.765
SMUV_0000843501 Syphacia muris SMUV_0000843501 I 0.763
DME_0000421901 Dracunculus medinensis DME_0000421901 I 0.763
EVEC_0000710001 Enterobius vermicularis EVEC_0000710001 I 0.763
TCNE_0000669301 Toxocara canis TCNE_0000669301 I 0.761
L898_g5709 Steinernema monticolum L898_g5709 I 0.761
L889_g21793 Steinernema feltiae L889_g21793 I 0.761
NEMVEDRAFT_v1g108258 Nematostella vectensis NEMVEDRAFT_v1g108258 I 0.761
ALUE_0002049001 Ascaris lumbricoides ALUE_0002049001 I 0.761
L596_g15116 Steinernema carpocapsae L596_g15116 I 0.759
L892_g9690 Steinernema scapterisci L892_g9690 I 0.759
BGIBMGA000604 Bombyx mori BGIBMGA000604 I 0.757