|
|
HHAL001092-PA
(Halyomorpha halys)
C2H2 ZF
|
TF Information |
|---|
| Pfam ID |
Interpro ID |
Gene ID |
CIS-BP ID |
Sequence source |
| PF00096 (zf-C2H2) |
IPR007087 |
HHAL001092-PA |
T144002_2.00 |
Misc (2018-Jan-19) |
| NCBI Gene Info:This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277). [provided by RefSeq, Dec 2016] |
Directly determined binding motifs |
|---|
| Name/Motif ID |
Species |
Forward |
Reverse |
Type/Study/Study ID |
SR
Score |
DBD
Identity |
| No direct experiments |
|
|
|
|
|
Motifs from related TFs |
|---|
| Name/Motif ID |
Species |
Forward |
Reverse |
Type/Study/Study ID |
SR
Score |
DBD
Identity |
scrt
M03673_2.00 |
Drosophila melanogaster |
RHGCAACAGGTGK |
MCACCTGTTGCDY |
SELEX
Nitta et al.(2015)
scrt_1
|
0.804
|
0.956
|
scrt
M06085_2.00 |
Drosophila melanogaster |
MCCACCTGTTG |
CAACAGGTGGK |
B1H
Zhu et al.(2011)
scrt_SANGER_2.5_FBgn0004880
|
0.804
|
0.956
|
scrt
M06086_2.00 |
Drosophila melanogaster |
DNKCAACAGGTGK |
MCACCTGTTGMNH |
B1H
Zhu et al.(2011)
scrt_SOLEXA_2.5_1_FBgn0004880
|
0.804
|
0.956
|
scrt
M06087_2.00 |
Drosophila melanogaster |
VMCACCTGTTGMN |
NKCAACAGGTGKB |
B1H
Zhu et al.(2011)
scrt_SOLEXA_2.5_2_FBgn0004880
|
0.804
|
0.956
|
SCRT1
M02929_2.00 |
Homo sapiens |
RHKCAACAGGTGKNH |
DNMCACCTGTTGMDY |
SELEX
Jolma et al.(2013)
SCRT1_1
|
0.792
|
0.842
|
SCRT1
M04655_2.00 |
Homo sapiens |
NKCAACAGGTD |
HACCTGTTGMN |
SELEX
Yin et al.(2017)
SCRT1_eDBD_HT-SELEX
|
0.792
|
0.842
|
SCRT1
M08397_2.00 |
Homo sapiens |
RWKCAACAGGTG |
CACCTGTTGMWY |
ChIP-seq
Schmitges et al.(2016)
Q9BWW7_1-4.RCADE
|
0.792
|
0.842
|
SCRT1
M04656_2.00 |
Homo sapiens |
NGCRACAGGTD |
HACCTGTYGCN |
SELEX
Yin et al.(2017)
SCRT1_eDBD_Methyl-HT-SELEX
|
0.792
|
0.842
|
CG12605
M03691_2.00 |
Drosophila melanogaster |
RHGCAACAGGTGN |
NCACCTGTTGCDY |
SELEX
Nitta et al.(2015)
CG12605_1
|
0.776
|
0.895
|
CG12605
M06139_2.00 |
Drosophila melanogaster |
CACCTGTKG |
CMACAGGTG |
B1H
Zhu et al.(2011)
CG12605_SANGER_10_FBgn0035481
|
0.776
|
0.895
|
CG12605
M06140_2.00 |
Drosophila melanogaster |
MCACCTGTKGVNN |
NNBCMACAGGTGK |
B1H
Zhu et al.(2011)
CG12605_SOLEXA_5_FBgn0035481
|
0.776
|
0.895
|
SCRT2
M02925_2.00 |
Homo sapiens |
RHGCAACAGGTGB |
VCACCTGTTGCDY |
SELEX
Jolma et al.(2013)
SCRT2_1
|
0.774
|
0.833
|
SCRT2
M04643_2.00 |
Homo sapiens |
NGCAACAGGTD |
HACCTGTTGCN |
SELEX
Yin et al.(2017)
SCRT2_eDBD_HT-SELEX
|
0.774
|
0.833
|
SCRT2
M04644_2.00 |
Homo sapiens |
NGCRACAGGTG |
CACCTGTYGCN |
SELEX
Yin et al.(2017)
SCRT2_eDBD_Methyl-HT-SELEX
|
0.774
|
0.833
|
| For this family, TFs with SR scores > 0.755 will likely have a similar motif |