HHAL005482-PA (Halyomorpha halys)
C2H2 ZF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source
PF00096 (zf-C2H2) IPR007087 HHAL005482-PA T144062_2.00 Misc (2018-Jan-19)
NCBI Gene Info:
This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277). [provided by RefSeq, Dec 2016]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
ttk
M05863_2.00 		Drosophila melanogaster
DTRTCCTKDN
NHMAGGAYAH		 SMiLE-seq
Isakova et al.(2017)
Ttk 		0.798 0.913
ttk
M06469_2.00 		Drosophila melanogaster
RTTATCCTK
MAGGATAAY		 B1H
Mathelier et al.(2014)
MA0460.1 		0.798 0.913
ttk
M06074_2.00 		Drosophila melanogaster
RSMAGGAYMTYB
VRAKRTCCTKSY		 B1H
Zhu et al.(2011)
ttk_FlyReg_FBgn0003870 		0.798 0.913
ttk
M06075_2.00 		Drosophila melanogaster
RTTATCCTK
MAGGATAAY		 B1H
Zhu et al.(2011)
ttk_NAR_FBgn0003870 		0.798 0.913
ttk
M06076_2.00 		Drosophila melanogaster
CHHCCCYTA
TARGGGDDG		 B1H
Zhu et al.(2011)
ttk-PA_SANGER_5_FBgn0003870 		0.798 0.913
ttk
M06077_2.00 		Drosophila melanogaster
TRTCCTK
MAGGAYA		 B1H
Zhu et al.(2011)
ttk-PF_SANGER_5_FBgn0003870 		0.798 0.913
ttk
M09665_2.00 		Drosophila melanogaster
RWKRTCCTKB
VMAGGAYMWY		 Misc
Kulakovskiy et al.(2009)
ttk 		0.798 0.913
ttk
M10378_2.00 		Drosophila melanogaster
SCAGGASC
GSTCCTGS		 Transfac
Matys et al.(2006)
I$TTK69_01 		0.798 0.913
For this family, TFs with SR scores > 0.755 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
HHAL005482-PA C2H2 ZF 106 134
HHAL005482-PA C2H2 ZF 142 165

Links

Other C2H2 ZF family TFs
Other Halyomorpha halys TFs

36 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
CLEC003829 Cimex lectularius CLEC003829 I 0.827
CLEC025104 Cimex lectularius CLEC025104 I 0.827
RPRC013755 Rhodnius prolixus RPRC013755 I 0.827
KGM_19334 Danaus plexippus KGM_19334 I 0.812
PHUM489940 Pediculus humanus PHUM489940 I 0.812
ACYPI002482 Acyrthosiphon pisum ACYPI002482 I 0.812
GM16443 Drosophila sechellia FBgn0171358 I 0.798
ttk Drosophila simulans FBgn0193021 I 0.798
GK12114 Drosophila willistoni FBgn0214125 I 0.798
GI23127 Drosophila mojavensis FBgn0145854 I 0.798
GJ23101 Drosophila virilis FBgn0210203 I 0.798
ttk Drosophila yakuba FBgn0228787 I 0.798
GH18648 Drosophila grimshawi FBgn0126115 I 0.798
ttk Drosophila pseudoobscura FBgn0075017 I 0.798
ttk Drosophila melanogaster FBgn0003870 D 0.798
GF22980 Drosophila ananassae FBgn0099974 I 0.798
GG11824 Drosophila erecta FBgn0104119 I 0.798
CPIJ009646 Culex quinquefasciatus CPIJ009646 I 0.794
CpipJ_CPIJ009646 Culex pipiens CpipJ_CPIJ009646 I 0.794
AAEL003947 Aedes aegypti AAEL003947 I 0.794
LCUP007919 Lucilia cuprina LCUP007919 I 0.792
MDOA014587 Musca domestica MDOA014587 I 0.792
ASTEI09331 Anopheles stephensi ASTEI09331 I 0.788
AATE018350 Anopheles atroparvus AATE018350 I 0.788
ASIS009996 Anopheles sinensis ASIS009996 I 0.788
ADIR010658 Anopheles dirus ADIR010658 I 0.788
SINV13240 Solenopsis invicta SINV13240 I 0.788
ACEP16670 Atta cephalotes ACEP16670 I 0.788
NV30328 Nasonia vitripennis NV30328 I 0.788
GB47059 Apis mellifera GB47059 I 0.788
TC013843 Tribolium castaneum TC013843 I 0.788
BGIBMGA007531 Bombyx mori BGIBMGA007531 I 0.788
AFAF006554 Anopheles farauti AFAF006554 I 0.782
ACOM028540 Anopheles coluzzii ACOM028540 I 0.779
AGAP003537 Anopheles gambiae AGAP003537 I 0.779
AQUA014152 Anopheles quadriannulatus AQUA014152 I 0.779