HHAL008065-PA (Halyomorpha halys)
C2H2 ZF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source
PF00096 (zf-C2H2) IPR007087 HHAL008065-PA T144092_2.00 Misc (2018-Jan-19)
NCBI Gene Info:
This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277). [provided by RefSeq, Dec 2016]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
BCL11B
M04453_2.00
Homo sapiens
GTGAACGBNDNNVCTACAC

GTGTAGBNNHNVCGTTCAC
SELEX
Yin et al.(2017)
BCL11B_eDBD_HT-SELEX
0.772 0.842
BCL11B
M04454_2.00
Homo sapiens
GTGAACGBNDNHVCTACAC

GTGTAGBDNHNVCGTTCAC
SELEX
Yin et al.(2017)
BCL11B_eDBD_Methyl-HT-SELEX
0.772 0.842
BCL11A
M07926_2.00
Homo sapiens
BTYTCASTTCCYYHH

DDRRGGAASTGARAV
ChIP-seq
Gerstein et al.(2012)
GM12878_BCL11A_HudsonAlpha
0.762 0.825
BCL11A
M08881_2.00
Homo sapiens
BHBYCABTTCCYBHNYN

NRNDVRGGAAVTGRVDV
Misc
Kulakovskiy et al.(2013)
BC11A_HUMAN.H11MO.0.A
0.762 0.825
BCL11A
M10187_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$BCL11A_02
0.762 0.825
For this family, TFs with SR scores > 0.755 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
HHAL008065-PA C2H2 ZF 347 369
HHAL008065-PA C2H2 ZF 375 397
HHAL008065-PA C2H2 ZF 709 731
HHAL008065-PA C2H2 ZF 737 759
HHAL008065-PA C2H2 ZF 767 788

Links

Other C2H2 ZF family TFs
Other Halyomorpha halys TFs

124 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action
RPRC001562 Rhodnius prolixus RPRC001562 I 0.811
PHUM606430 Pediculus humanus PHUM606430 I 0.807
Ocbimv22018271m.g Octopus bimaculoides Ocbimv22018271m.g I 0.793
L798_02171 Zootermopsis nevadensis L798_02171 I 0.793
SMAR003355 Strigamia maritima SMAR003355 I 0.792
ACYPI007319 Acyrthosiphon pisum ACYPI007319 I 0.786
ISCW016418 Ixodes scapularis ISCW016418 I 0.785
ADIR010253 Anopheles dirus ADIR010253 N 0.784
ENSLOCG00000008679 Lepisosteus oculatus ENSLOCG00000008679 I 0.774
ENSONIG00000011060 Oreochromis niloticus ENSONIG00000011060 I 0.774
bcl11ba Takifugu rubripes ENSTRUG00000003531 I 0.774
bcl11ba Oryzias latipes ENSORLG00000010826 I 0.774
bcl11ba Tetraodon nigroviridis ENSTNIG00000008283 I 0.774
Sakowv30026316m.g Saccoglossus kowalevskii Sakowv30026316m.g I 0.774
BGLB012676 Biomphalaria glabrata BGLB012676 I 0.773
ASIS012904 Anopheles sinensis ASIS012904 N 0.773
AARA004246 Anopheles arabiensis AARA004246 N 0.773
im:7142702 Oryzias latipes ENSORLG00000010488 I 0.772
ENSPFOG00000007224 Poecilia formosa ENSPFOG00000007224 I 0.772
ENSPSIG00000013079 Pelodiscus sinensis ENSPSIG00000013079 I 0.772
ENSPPYG00000006131 Pongo abelii ENSPPYG00000006131 I 0.772
ENSONIG00000001067 Oreochromis niloticus ENSONIG00000001067 I 0.772
Bcl11b Mus musculus ENSMUSG00000048251 I 0.772
BCL11B Monodelphis domestica ENSMODG00000012964 I 0.772
ENSNLEG00000000711 Nomascus leucogenys ENSNLEG00000000711 I 0.772
BCL11B Ornithorhynchus anatinus ENSOANG00000014770 I 0.772
BCL11B Otolemur garnettii ENSOGAG00000033204 I 0.772
BCL11B Pan troglodytes ENSPTRG00000006707 I 0.772
BCL11B Pteropus vampyrus ENSPVAG00000015516 I 0.772
ENSXMAG00000020344 Xiphophorus maculatus ENSXMAG00000020344 I 0.772
im:7142702 Takifugu rubripes ENSTRUG00000018074 I 0.772
Gfo_R006733 Geospiza fortis Gfo_R006733 I 0.772
ENSP00000349723 Macaca fascicularis ENSP00000349723 I 0.772
Afo_R004626 Aptenodytes forsteri Afo_R004626 I 0.772
Cmyd_10012109 Chelonia mydas Cmyd_10012109 I 0.772
Pvit_09536 Pogona vitticeps Pvit_09536 I 0.772
BCL11B Macaca mulatta ENSMMUG00000003261 I 0.772
ENSSHAG00000009291 Sarcophilus harrisii ENSSHAG00000009291 I 0.772
Bcl11b Rattus norvegicus ENSRNOG00000005776 I 0.772
BCL11B Sus scrofa ENSSSCG00000002507 I 0.772
ENSSTOG00000021531 Ictidomys tridecemlineatus ENSSTOG00000021531 I 0.772
BCL11B Taeniopygia guttata ENSTGUG00000012711 I 0.772
Aan_R000616 Calypte anna Aan_R000616 I 0.772
ENSPANG00000004313 Papio anubis ENSPANG00000004313 I 0.772
ENSGMOG00000012414 Gadus morhua ENSGMOG00000012414 I 0.772
BCL11B Homo sapiens ENSG00000127152 D 0.772
ENSCPOG00000009946 Cavia porcellus ENSCPOG00000009946 I 0.772
BCL11B Callithrix jacchus ENSCJAG00000006713 I 0.772
BCL11B Gorilla gorilla ENSGGOG00000001232 I 0.772
ENSGALG00000028278 Gallus gallus ENSGALG00000028278 I 0.772
bcl11ba Gasterosteus aculeatus ENSGACG00000013118 I 0.772
BCL11B Dasypus novemcinctus ENSDNOG00000012677 I 0.772
ENSGALG00000011127 Gallus gallus ENSGALG00000011127 I 0.772
BCL11B Canis familiaris ENSCAFG00000017809 I 0.772
ENSCSAG00000010477 Chlorocebus sabaeus ENSCSAG00000010477 I 0.772
ENSACAG00000013085 Anolis carolinensis ENSACAG00000013085 I 0.772
BCL11B Bos taurus ENSBTAG00000018019 I 0.772
ENSAMXG00000015839 Astyanax mexicanus ENSAMXG00000015839 I 0.772
BCL11B Loxodonta africana ENSLAFG00000009254 I 0.772
ENSAPLG00000006283 Anas platyrhynchos ENSAPLG00000006283 I 0.772
AMEC015245 Anopheles melas AMEC015245 I 0.771
im:7142702 Gasterosteus aculeatus ENSGACG00000005537 I 0.770
ENSXMAG00000019910 Xiphophorus maculatus ENSXMAG00000019910 I 0.770
ACUA026076 Anopheles culicifacies ACUA026076 N 0.770
im:7142702 Danio rerio ENSDARG00000067727 I 0.770
ENSPFOG00000003609 Poecilia formosa ENSPFOG00000003609 I 0.770
ENSAMXG00000018130 Astyanax mexicanus ENSAMXG00000018130 I 0.770
BCL11B Tursiops truncatus ENSTTRG00000012140 I 0.767
bcl11aa Danio rerio ENSDARG00000061352 I 0.765
bcl11ab Danio rerio ENSDARG00000063153 I 0.765
bcl11ab Takifugu rubripes ENSTRUG00000013751 I 0.765
CLEC002851 Cimex lectularius CLEC002851 N 0.765
bcl11ab Tetraodon nigroviridis ENSTNIG00000012076 I 0.765
bcl11ab Oryzias latipes ENSORLG00000013169 I 0.765
ENSONIG00000018855 Oreochromis niloticus ENSONIG00000018855 I 0.765
ENSPFOG00000007302 Poecilia formosa ENSPFOG00000007302 I 0.765
Cmyd_10008592 Chelonia mydas Cmyd_10008592 I 0.764
ENSLACG00000003560 Latimeria chalumnae ENSLACG00000003560 I 0.762
ENSBTAP00000023987-D2 Bos grunniens ENSBTAP00000023987-D2 I 0.762
ENSP00000338774 Macaca fascicularis ENSP00000338774 I 0.762
BCL11A Loxodonta africana ENSLAFG00000003101 I 0.762
Alligator_sinensis_CCG008166.1 Alligator sinensis Alligator_sinensis_CCG008166.1 I 0.762
Afo_R011357 Aptenodytes forsteri Afo_R011357 I 0.762
Aan_R006276 Calypte anna Aan_R006276 I 0.762
Gfo_R008167 Geospiza fortis Gfo_R008167 I 0.762
BCL11A Callithrix jacchus ENSCJAG00000009226 I 0.762
ENSAPLG00000007735 Anas platyrhynchos ENSAPLG00000007735 I 0.762
ENSAMEG00000015813 Ailuropoda melanoleuca ENSAMEG00000015813 I 0.762
Bcl11a Mus musculus ENSMUSG00000000861 I 0.762
BCL11A Meleagris gallopavo ENSMGAG00000013042 I 0.762
BCL11A Anolis carolinensis ENSACAG00000015159 I 0.762
ENSMMUG00000011303 Macaca mulatta ENSMMUG00000011303 I 0.762
ENSMEUG00000001829 Macropus eugenii ENSMEUG00000001829 I 0.762
bcl11a Xenopus tropicalis XB-GENE-486641 I 0.762
Pvit_18645 Pogona vitticeps Pvit_18645 I 0.762
BCL11A Oryctolagus cuniculus ENSOCUG00000023948 I 0.762
BCL11A Ornithorhynchus anatinus ENSOANG00000012402 I 0.762
ENSLOCG00000016135 Lepisosteus oculatus ENSLOCG00000016135 I 0.762
BCL11A Cavia porcellus ENSCPOG00000007587 I 0.762
ENSGMOG00000015842 Gadus morhua ENSGMOG00000015842 I 0.762
ENSFALG00000011123 Ficedula albicollis ENSFALG00000011123 I 0.762
BCL11A Erinaceus europaeus ENSEEUG00000010958 I 0.762
BCL11A Microcebus murinus ENSMICG00000015052 I 0.762
Bcl11a Dipodomys ordii ENSDORG00000010064 I 0.762
BCL11A Taeniopygia guttata ENSTGUG00000006790 I 0.762
BCL11A Felis catus ENSFCAG00000027154 I 0.762
ENSSHAG00000015804 Sarcophilus harrisii ENSSHAG00000015804 I 0.762
BCL11A Homo sapiens ENSG00000119866 D 0.762
BCL11A Sus scrofa ENSSSCG00000008392 I 0.762
ENSSTOG00000004523 Ictidomys tridecemlineatus ENSSTOG00000004523 I 0.762
BCL11A Pteropus vampyrus ENSPVAG00000000042 I 0.762
BCL11A Dasypus novemcinctus ENSDNOG00000019842 I 0.762
ENSGALG00000007866 Gallus gallus ENSGALG00000007866 I 0.762
ENSPSIG00000013644 Pelodiscus sinensis ENSPSIG00000013644 I 0.762
LotgiG139415 Lottia gigantea LotgiG139415 I 0.762
BCL11A Gorilla gorilla ENSGGOG00000007337 I 0.762
Bcl11a Rattus norvegicus ENSRNOG00000007049 I 0.762
BCL11A Vicugna pacos ENSVPAG00000000491 I 0.762
bcl11ab Gasterosteus aculeatus ENSGACG00000019222 I 0.762
ENSTSYG00000009153 Tarsius syrichta ENSTSYG00000009153 I 0.762
BCL11A Tursiops truncatus ENSTTRG00000006191 I 0.762
ENSOCUG00000024296 Oryctolagus cuniculus ENSOCUG00000024296 I 0.760
im:7142702 Tetraodon nigroviridis ENSTNIG00000009693 I 0.760
SPU_018909 Strongylocentrotus purpuratus SPU_018909 I 0.760