HHAL008603-PA (Halyomorpha halys)
C2H2 ZF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source
PF00096 (zf-C2H2) IPR007087 HHAL008603-PA T144098_2.00 Misc (2018-Jan-19)
NCBI Gene Info:
This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277). [provided by RefSeq, Dec 2016]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
No TFs with similar DNA binding domains

DNA Binding Domains

Protein ID Domain From To Sequence
HHAL008603-PA C2H2 ZF 190 214
HHAL008603-PA C2H2 ZF 220 244
HHAL008603-PA C2H2 ZF 250 272

Links

Other C2H2 ZF family TFs
Other Halyomorpha halys TFs

16 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action
CLEC005479 Cimex lectularius CLEC005479 N 0.790
RPRC001510 Rhodnius prolixus RPRC001510 N 0.781
NV23733 Nasonia vitripennis NV23733 I 0.777
SINV19724 Solenopsis invicta SINV19724 I 0.777
ACEP10867 Atta cephalotes ACEP10867 I 0.777
KLF10 Takifugu rubripes ENSTRUG00000010298 I 0.763
LDEC016289 Leptinotarsa decemlineata LDEC016289 I 0.761
GB45040 Apis mellifera GB45040 I 0.761
Aqu1.217685 Amphimedon queenslandica Aqu1.217685 N 0.760
KLF10 Gasterosteus aculeatus ENSGACG00000004632 I 0.759
ENSONIG00000016428 Oreochromis niloticus ENSONIG00000016428 I 0.759
YQE_06283 Dendroctonus ponderosae YQE_06283 I 0.758
L798_11067 Zootermopsis nevadensis L798_11067 I 0.757
ENSPMAG00000001515 Petromyzon marinus ENSPMAG00000001515 I 0.757
Alligator_sinensis_CCG003669.1 Alligator sinensis Alligator_sinensis_CCG003669.1 I 0.756
zgc:153115 Oryzias latipes ENSORLG00000008372 I 0.756