TBX20 (Homo sapiens)
T-box

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00907 (T-box) IPR001699 ENSG00000164532 T149488_1.02 Ensembl (2011-Oct-26) Link out
NCBI Gene Info:
This gene encodes a T-box family member. The T-box family members share a common DNA binding domain, termed the T-box, and they are transcription factors involved in the regulation of developmental processes. This gene is essential for heart development. Mutations in this gene are associated with diverse cardiac pathologies, including defects in septation, valvulogenesis and cardiomyopathy. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID DBD
Identity
TBX20
M5883_1.02
Homo sapiens
TCACRCBYTMACACCT

AGGTGTKARVGYGTGA
SELEX
Jolma et al.(2013)
TBX20_1
(Direct)
TBX20
M5884_1.02
Homo sapiens
AVGTGTSAHWTTCACACCT

AGGTGTGAAWDTSACACBT
SELEX
Jolma et al.(2013)
TBX20_2
(Direct)
TBX20
M5885_1.02
Homo sapiens
NNNDAGGTGTGAAND

HNTTCACACCTHNNN
SELEX
Jolma et al.(2013)
TBX20_3
(Direct)
TBX20
M5886_1.02
Homo sapiens
DAGGTGTGAWR

YWTCACACCTH
SELEX
Jolma et al.(2013)
TBX20_4
(Direct)
TBX20
M5887_1.02
Homo sapiens
TSACAMCNTMACACCT

AGGTGTKANGKTGTSA
SELEX
Jolma et al.(2013)
TBX20_5
(Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID DBD
Identity
Tbx20
M1631_1.02
Mus musculus
NRRGTGTBAN

NTVACACYYN
PBM
Weirauch et al.(2013)
pTH3777
0.995
TBX1
M5876_1.02
Homo sapiens
AGGTGTGAWWTTCACACCT

AGGTGTGAAWWTCACACCT
SELEX
Jolma et al.(2013)
TBX1_2
0.613
TBX1
M5879_1.02
Homo sapiens
YTCACACCTDKAGGTGTGAA

TTCACACCTMHAGGTGTGAR
SELEX
Jolma et al.(2013)
TBX1_5
0.613
TBX1
M5875_1.02
Homo sapiens
ARGTGTKAAAWHARGTGTGA

TCACACYTDWTTTMACACYT
SELEX
Jolma et al.(2013)
TBX1_1
0.613
TBX1
M5878_1.02
Homo sapiens
YYTCACACMTYWRAGGTGTG

TTTCACACCTYWRAKGTGTG
SELEX
Jolma et al.(2013)
TBX1_4
0.613
Tbx1
M4020_1.02
Mus musculus Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$TBX1_07
0.613
TBX1
M5877_1.02
Homo sapiens
AGGTGTGA

TCACACCT
SELEX
Jolma et al.(2013)
TBX1_3
0.613
Tbx1
M1628_1.02
Mus musculus
NRGTGTGAANN

NNTTCACACYN
PBM
Weirauch et al.(2013)
pTH3822
0.613
XP_001195863.1
M1640_1.02
Strongylocentrotus purpuratus
TVACACCT

AGGTGTBA
PBM
Weirauch et al.(2014)
pTH9340
0.601
For this family, TFs with SR scores > 0.600 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000373862 T-box 101 289
ENSP00000386170 T-box 101 289

Links

Other T-box family TFs
Other Homo sapiens TFs

0 Related TFs

">No related TF found