CG43689 (Drosophila melanogaster)
C2HC ZF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF01530 (zf-C2HC) IPR002515 FBgn0263772 T159342_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in autosomal dominant non-syndromic intellectual disability 39. Orthologous to human ST18 (ST18 C2H2C-type zinc finger transcription factor); MYT1 (myelin transcription factor 1); and MYT1L (myelin transcription factor 1 like). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
ztf-11
M00650_2.00 		Caenorhabditis elegans
VAAGTTTN
NAAACTTB		 PBM
Narasimhan et al.(2015)
pTH9925 		0.707 0.707
For this family, TFs with SR scores > 0.700 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
FBpp0302629 C2HC ZF 1108 1136
FBpp0302629 C2HC ZF 1153 1181
FBpp0302630 C2HC ZF 415 443
FBpp0302630 C2HC ZF 1166 1194
FBpp0302630 C2HC ZF 1211 1239
FBpp0302631 C2HC ZF 409 432
FBpp0302631 C2HC ZF 438 466
FBpp0302631 C2HC ZF 1189 1217
FBpp0302631 C2HC ZF 1234 1262
FBpp0302632 C2HC ZF 1108 1136
FBpp0302632 C2HC ZF 1153 1181
FBpp0302633 C2HC ZF 415 443
FBpp0302633 C2HC ZF 1166 1194
FBpp0302633 C2HC ZF 1211 1239
FBpp0308738 C2HC ZF 1078 1106
FBpp0308738 C2HC ZF 1123 1151

Links

Other C2HC ZF family TFs
Other Drosophila melanogaster TFs

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117 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action