TF Information

HAP2 *(Saccharomyces cerevisiae)* CBF/NF-Y
Pfam ID	Interpro ID	Gene ID	CIS-BP ID	Sequence source	Animal TF db
PF02045 (CBFB_NFYA)	IPR001289	YGL237C	T160514_2.00	Ensembl (2018-Dec-8)	Link out
NCBI Gene Info: Contributes to DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in carbon catabolite activation of transcription from RNA polymerase II promoter and regulation of cellular respiration. Located in nucleus. Part of CCAAT-binding activity factor complex. Orthologous to human NFYA (nuclear transcription factor Y subunit alpha). [provided by Alliance of Genome Resources, Apr 2022]
Directly determined binding motifs
Name/Motif ID	Species	Forward	Reverse	Type/Study/Study ID	SR Score	DBD Identity
HAP2 M08452_2.00	Saccharomyces cerevisiae	TTGGH	DCCAA	COMPILED Mathelier et al.(2014) MA0313.1	(Direct)	(Direct)
Motifs from related TFs
Name/Motif ID	Species	Forward	Reverse	Type/Study/Study ID	SR Score	DBD Identity
NFYA M08104_2.00	Homo sapiens	NSTGATTGGYB	VRCCAATCASN	ChIP-seq Mathelier et al.(2014) MA0060.3	0.732	0.732
NFYA M09018_2.00	Homo sapiens	YKBYSATTGGYYRV	BYRRCCAATSRVMR	Misc Kulakovskiy et al.(2013) NFYA_HUMAN.H11MO.0.A	0.732	0.732
Nfya M09019_2.00	Mus musculus	YKBYSATTGGYYRV	BYRRCCAATSRVMR	Misc Kulakovskiy et al.(2013) NFYA_MOUSE.H11MO.0.A	0.732	0.732
NFYA M10403_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$NFYA_02	0.732	0.732
NFYA M10404_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$NFYA_Q5	0.732	0.732
NFYA M10405_2.00	Homo sapiens	NYTGATTGGYTAVH	DBTARCCAATCARN	Transfac Matys et al.(2006) V$NFY_C	0.732	0.732
For this family, TFs with SR scores > 0.700* will likely have a similar motif*