TF Information

HHAL001434-PA *(Halyomorpha halys)* CSD
Pfam ID	Interpro ID	Gene ID	CIS-BP ID	Sequence source
PF00313 (CSD)	IPR002059	HHAL001434-PA	T165508_2.00	Misc (2018-Jan-19)
NCBI Gene Info: This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277). [provided by RefSeq, Dec 2016]
Directly determined binding motifs
Name/Motif ID	Species	Forward	Reverse	Type/Study/Study ID	SR Score	DBD Identity
No direct experiments
Motifs from related TFs
Name/Motif ID	Species	Forward	Reverse	Type/Study/Study ID	SR Score	DBD Identity
YBX1 M04661_2.00	Homo sapiens	GRTGGWACR	YGTWCCAYC	SELEX Yin et al.(2017) YBX1_eDBD_HT-SELEX	0.838	0.838
YBX1 M10411_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$YB1_Q3	0.838	0.838
YBX1 M10412_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$YB1_Q4	0.838	0.838
YBX1 M04662_2.00	Homo sapiens	GRTGKDRCD	HGYHMCAYC	SELEX Yin et al.(2017) YBX1_eDBD_Methyl-HT-SELEX	0.838	0.838
NEMVEDRAFT_v1g104083 M01207_2.00	Nematostella vectensis	NNNDDHRN	NYDHHNNN	PBM Lambert et al.(2019) pTH9768	0.730	0.730
For this family, TFs with SR scores > 0.700* will likely have a similar motif*