CUX1 (Homo sapiens)
CUT,Homeodomain

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF02376 (CUT)
PF00046 (Homeobox) 		IPR003350
IPR001356 		ENSG00000257923 T167063_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
CUX1
M01501_2.00		 Homo sapiens
NDATYRRNN
NNYYRATHN		 PBM
Yin et al.(2017b)
CUX1_5mCG		 (Direct) (Direct)
CUX1
M01502_2.00		 Homo sapiens
NDATYGRHN
NDYCRATHN		 PBM
Yin et al.(2017b)
CUX1_Cytosine		 (Direct) (Direct)
CUX1
M02946_2.00		 Homo sapiens
ATCRATHNNNDATCRAT
ATYGATHNNNDATYGAT		 SELEX
Jolma et al.(2013)
CUX1_1		 (Direct) (Direct)
CUX1
M02947_2.00		 Homo sapiens
ATCRATHNNNNDATCRAT
ATYGATHNNNNDATYGAT		 SELEX
Jolma et al.(2013)
CUX1_2		 (Direct) (Direct)
CUX1
M02948_2.00		 Homo sapiens
TDATCRATNN
NNATYGATHA		 SELEX
Jolma et al.(2013)
CUX1_3		 (Direct) (Direct)
CUX1
M04679_2.00		 Homo sapiens
NDATCRATNN
NNATYGATHN		 SELEX
Yin et al.(2017)
CUX1_eDBD_HT-SELEX		 (Direct) (Direct)
CUX1
M04680_2.00		 Homo sapiens
NBATTGATHR
YDATCAATVN		 SELEX
Yin et al.(2017)
CUX1_eDBD_Methyl-HT-SELEX		 (Direct) (Direct)
CUX1
M09023_2.00		 Homo sapiens
RBRVNDATYGRTBN
NVAYCRATHNBYVY		 Misc
Kulakovskiy et al.(2013)
CUX1_HUMAN.H11MO.0.C		 (Direct) (Direct)
CUX1
M10422_2.00		 Homo sapiens
CCAATAATCRAT
ATYGATTATTGG		 Transfac
Matys et al.(2006)
V$CDP_01		 (Direct) (Direct)
CUX1
M10423_2.00		 Homo sapiens
DWDATCGATYADHDH
DHDHTRATCGATHWH		 Transfac
Matys et al.(2006)
V$CDP_02		 (Direct) (Direct)
CUX1
M10424_2.00		 Homo sapiens
SCVATCRATN
NATYGATBGS		 Transfac
Matys et al.(2006)
V$CDPCR1_01		 (Direct) (Direct)
CUX1
M10425_2.00		 Homo sapiens
CVATABNTATYKGTG
CACMRATANVTATBG		 Transfac
Matys et al.(2006)
V$CDPCR3_01		 (Direct) (Direct)
CUX1
M10426_2.00		 Homo sapiens
SVSATCRATB
VATYGATSBS		 Transfac
Matys et al.(2006)
V$CDPCR3HD_01		 (Direct) (Direct)
CUX1
M10427_2.00		 Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$CDP_Q6_01		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Cux1
M09024_2.00 		Mus musculus
RBRVNDATYGRTBN
NVAYCRATHNBYVY		 Misc
Kulakovskiy et al.(2013)
CUX1_MOUSE.H11MO.0.C 		0.993 0.993
CUX1
M10416_2.00 		Canis familiaris
DHDATYGATYADYDW
WHRHTRATCRATHDH		 Transfac
Matys et al.(2006)
V$CLOX_01 		0.993 0.993
CUX2
M02940_2.00 		Homo sapiens
ATCRATAHNNDWATCGAT
ATCGATWHNNDTATYGAT		 SELEX
Jolma et al.(2013)
CUX2_1 		0.885 0.885
CUX2
M02941_2.00 		Homo sapiens
DDATYGATYA
TRATCRATHH		 SELEX
Jolma et al.(2013)
CUX2_2 		0.885 0.885
CUX2
M04665_2.00 		Homo sapiens
NTRATCGATYRN
NYRATCGATYAN		 SELEX
Yin et al.(2017)
CUX2_eDBD_HT-SELEX 		0.885 0.885
CUX2
M04666_2.00 		Homo sapiens
BYRATCGATYRB
VYRATCGATYRV		 SELEX
Yin et al.(2017)
CUX2_eDBD_Methyl-HT-SELEX 		0.885 0.885
Cux2
M09025_2.00 		Mus musculus
NBBATTGATYD
HRATCAATVVN		 Misc
Kulakovskiy et al.(2013)
CUX2_MOUSE.H11MO.0.C 		0.878 0.878
For this family, TFs with SR scores > 0.700 will likely have a similar motif

Experimental Constructs

Motif ID Domain From To Sequence
M01501_2.00 CUT 39 116
M01501_2.00 CUT 431 507
M01501_2.00 CUT 614 692
M01501_2.00 Homeodomain 737 793
M01502_2.00 CUT 39 116
M01502_2.00 CUT 431 507
M01502_2.00 CUT 614 692
M01502_2.00 Homeodomain 737 793

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000292535 CUT 547 624
ENSP00000292535 CUT 939 1015
ENSP00000292535 CUT 1122 1200
ENSP00000292535 Homeodomain 1245 1301
ENSP00000353401 CUT 558 635
ENSP00000353401 CUT 950 1026
ENSP00000353401 CUT 1133 1211
ENSP00000353401 Homeodomain 1256 1312
ENSP00000446630 CUT 547 624
ENSP00000446630 CUT 917 993
ENSP00000446630 CUT 1100 1178
ENSP00000446630 Homeodomain 1223 1279
ENSP00000447373 CUT 547 624
ENSP00000447373 CUT 883 959
ENSP00000447373 CUT 1066 1144
ENSP00000447373 Homeodomain 1189 1245
ENSP00000450125 CUT 445 522
ENSP00000450125 CUT 837 913
ENSP00000450125 CUT 1020 1098
ENSP00000450125 Homeodomain 1143 1199
ENSP00000451558 CUT 445 522
ENSP00000451558 CUT 781 857
ENSP00000451558 CUT 964 1042
ENSP00000451558 Homeodomain 1087 1143

Links

Other CUT,Homeodomain family TFs
Other Homo sapiens TFs

Invalid Input OrderBy

110 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action