FBXL19 (Homo sapiens)
CxxC

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF02008 (zf-CXXC) IPR002857 ENSG00000099364 T167981_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
This gene encodes a member of the Skp1-Cullin-F-box family of E3 ubiquitin ligases. The encoded protein is reported to bind to the transmembrane receptor interleukin 1 receptor-like 1 and regulate its ubiquitination and degradation. This protein has been linked to the regulation of pulmonary inflammation and psoriasis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
FBXL19
M01916_2.00
Tetraodon nigroviridis
NNNNCGNN

NNCGNNNN
PBM
Weirauch et al.(2014)
pTH8570
0.915 0.915
A6H8I1_DANRE
M01906_2.00
Danio rerio
CGTACGYA

TRCGTACG
PBM
Weirauch et al.(2014)
pTH9257
0.872 0.872
kdm2ba
M01909_2.00
Danio rerio
NNNNCGN

NCGNNNN
PBM
Weirauch et al.(2014)
pTH8577
0.872 0.872
KDM2B
M01911_2.00
Homo sapiens
NNNNNNCGN

NCGNNNNNN
PBM
Weirauch et al.(2014)
pTH9191
0.851 0.851
KDM2A
M01915_2.00
Meleagris gallopavo
NNNNYRNNNN

NNNNYRNNNN
PBM
Weirauch et al.(2014)
pTH9212
0.809 0.809
kdm2aa
M01910_2.00
Danio rerio
NCGNNNNNN

NNNNNNCGN
PBM
Weirauch et al.(2014)
pTH8585
0.766 0.766
For this family, TFs with SR scores > 0.700 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000339712 CxxC 11 57
ENSP00000369666 CxxC 31 77
ENSP00000454344 CxxC 11 57
ENSP00000455529 CxxC 11 57
ENSP00000455871 CxxC 11 57

Links

Other CxxC family TFs
Other Homo sapiens TFs

212 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action
29908.m006047 Ricinus communis 29908.m006047 N 0.000
30055.m001542 Ricinus communis 30055.m001542 N 0.000
30061.m000294 Ricinus communis 30061.m000294 N 0.000
Aquca_004_00109 Aquilegia coerulea Aquca_004_00109 N 0.000
Aquca_006_00227 Aquilegia coerulea Aquca_006_00227 N 0.000
Aquca_040_00077 Aquilegia coerulea Aquca_040_00077 N 0.000
WIP3 Arabidopsis thaliana AT1G08290 N 0.000
BGIOSGA031001 Oryza indica BGIOSGA031001 N 0.000
Bo5g008880 Brassica oleracea Bo5g008880 N 0.000
Bo5g081360 Brassica oleracea Bo5g081360 N 0.000
Bo8g112550 Brassica oleracea Bo8g112550 N 0.000
Bostr.1040s0072 Boechera stricta Bostr.1040s0072 N 0.000
Bostr.25219s0116 Boechera stricta Bostr.25219s0116 N 0.000
Bra018638 Brassica rapa Bra018638 N 0.000
Bra031621 Brassica rapa Bra031621 N 0.000
BRADI3G39820 Brachypodium distachyon BRADI3G39820 N 0.000
BRADI4G33557 Brachypodium distachyon BRADI4G33557 N 0.000
Cagra.0764s0003 Capsella grandiflora Cagra.0764s0003 N 0.000
Cagra.4395s0018 Capsella grandiflora Cagra.4395s0018 N 0.000
Carubv10009617m.g Capsella rubella Carubv10009617m.g N 0.000
Carubv10012266m.g Capsella rubella Carubv10012266m.g N 0.000
cassava13451.valid.m1 Manihot esculenta cassava13451.valid.m1 N 0.000
cassava16214.m1 Manihot esculenta cassava16214.m1 N 0.000
cassava39829.m1 Manihot esculenta cassava39829.m1 N 0.000
cassava44390.m1 Manihot esculenta cassava44390.m1 N 0.000
Ca_07051 Cicer arietinum Ca_07051 N 0.000
Ca_27078 Cicer arietinum Ca_27078 N 0.000
chr3.CM1144.10.nc Lotus japonicus chr3.CM1144.10.nc N 0.000
Ciclev10003648m.g Citrus clementina Ciclev10003648m.g N 0.000
Ciclev10028757m.g Citrus clementina Ciclev10028757m.g N 0.000
Cla000184 Citrullus lanatus Cla000184 N 0.000
Cla002714 Citrullus lanatus Cla002714 N 0.000
Cla015481 Citrullus lanatus Cla015481 N 0.000
Cucsa.050260 Cucumis sativus Cucsa.050260 N 0.000
Cucsa.065460 Cucumis sativus Cucsa.065460 N 0.000
Cucsa.199850 Cucumis sativus Cucsa.199850 N 0.000
Cucsa.248320 Cucumis sativus Cucsa.248320 N 0.000
Eucgr.B03870 Eucalyptus grandis Eucgr.B03870 N 0.000
Eucgr.F00336 Eucalyptus grandis Eucgr.F00336 N 0.000
evm.TU.contig_31438 Carica papaya evm.TU.contig_31438 N 0.000
evm.TU.contig_35924 Carica papaya evm.TU.contig_35924 N 0.000
evm.TU.supercontig_1.215 Carica papaya evm.TU.supercontig_1.215 N 0.000
F775_14972 Aegilops tauschii F775_14972 N 0.000
WIP3 Arabidopsis lyrata fgenesh1_pg.C_scaffold_1000684 N 0.000
gene22042-v1.0-hybrid Fragaria vesca gene22042-v1.0-hybrid N 0.000
GLYMA08G16390 Glycine max GLYMA08G16390 N 0.000
GLYMA11G19060 Glycine max GLYMA11G19060 N 0.000
GLYMA12G09400 Glycine max GLYMA12G09400 N 0.000
GLYMA12G30930 Glycine max GLYMA12G30930 N 0.000
GLYMA12G36660 Glycine max GLYMA12G36660 N 0.000
GLYMA13G01720 Glycine max GLYMA13G01720 N 0.000
GLYMA13G27371 Glycine max GLYMA13G27371 N 0.000
GLYMA13G39370 Glycine max GLYMA13G39370 N 0.000
GLYMA14G35140 Glycine max GLYMA14G35140 N 0.000
GLYMA15G42870 Glycine max GLYMA15G42870 N 0.000
Gorai.001G121700 Gossypium raimondii Gorai.001G121700 N 0.000
Gorai.004G037000 Gossypium raimondii Gorai.004G037000 N 0.000
Gorai.004G065400 Gossypium raimondii Gorai.004G065400 N 0.000
Gorai.006G111400 Gossypium raimondii Gorai.006G111400 N 0.000
Gorai.007G177300 Gossypium raimondii Gorai.007G177300 N 0.000
Gorai.010G039600 Gossypium raimondii Gorai.010G039600 N 0.000
GRMZM2G071101 Zea mays GRMZM2G071101 N 0.000
GRMZM2G084014 Zea mays GRMZM2G084014 N 0.000
GRMZM2G445684 Zea mays GRMZM2G445684 N 0.000
GSMUA_Achr3G03850_001 Musa acuminata GSMUA_Achr3G03850_001 N 0.000
GSMUA_Achr4G01560_001 Musa acuminata GSMUA_Achr4G01560_001 N 0.000
GSMUA_Achr9G12600_001 Musa acuminata GSMUA_Achr9G12600_001 N 0.000
LjSGA_032817.1 Lotus japonicus LjSGA_032817.1 N 0.000
LPERR08G16620 Leersia perrieri LPERR08G16620 N 0.000
LPERR09G10700 Leersia perrieri LPERR09G10700 N 0.000
Lus10004887.g Linum usitatissimum Lus10004887.g N 0.000
Lus10020597.g Linum usitatissimum Lus10020597.g N 0.000
Lus10029525.g Linum usitatissimum Lus10029525.g N 0.000
Lus10033454.g Linum usitatissimum Lus10033454.g N 0.000
Lus10039613.g Linum usitatissimum Lus10039613.g N 0.000
MDP0000131949 Malus domestica MDP0000131949 N 0.000
MDP0000142494 Malus domestica MDP0000142494 N 0.000
MDP0000144266 Malus domestica MDP0000144266 N 0.000
MDP0000300013 Malus domestica MDP0000300013 N 0.000
MDP0000573922 Malus domestica MDP0000573922 N 0.000
mgf022319m Mimulus guttatus mgf022319m N 0.000
mgf022981m Mimulus guttatus mgf022981m N 0.000
MLOC_2787 Hordeum vulgare MLOC_2787 N 0.000
OB08G26650 Oryza brachyantha OB08G26650 N 0.000
OBART08G19670 Oryza barthii OBART08G19670 N 0.000
OGLUM08G20830 Oryza glumaepatula OGLUM08G20830 N 0.000
OGLUM09G15150 Oryza glumaepatula OGLUM09G15150 N 0.000
OMERI08G16450 Oryza meridionalis OMERI08G16450 N 0.000
OMERI09G11270 Oryza meridionalis OMERI09G11270 N 0.000
ONIVA08G21960 Oryza nivara ONIVA08G21960 N 0.000
ONIVA09G15100 Oryza nivara ONIVA09G15100 N 0.000
OPUNC08G17810 Oryza punctata OPUNC08G17810 N 0.000
OPUNC09G12930 Oryza punctata OPUNC09G12930 N 0.000
orange1.1g037179m.g Citrus sinensis orange1.1g037179m.g N 0.000
orange1.1g037234m.g Citrus sinensis orange1.1g037234m.g N 0.000
orange1.1g039549m.g Citrus sinensis orange1.1g039549m.g N 0.000
ORGLA08G0173000 Oryza glaberrima ORGLA08G0173000 N 0.000
ORGLA09G0111700 Oryza glaberrima ORGLA09G0111700 N 0.000
ORUFI09G15680 Oryza rufipogon ORUFI09G15680 N 0.000
OS08G0504000 Oryza sativa OS08G0504000 N 0.000
OS09G0485600 Oryza sativa OS09G0485600 N 0.000
Pavir.Ba01731 Panicum virgatum Pavir.Ba01731 N 0.000
Pavir.Fa00506 Panicum virgatum Pavir.Fa00506 N 0.000
Pavir.Fb01879 Panicum virgatum Pavir.Fb01879 N 0.000
PGSC0003DMG400006808 Solanum tuberosum PGSC0003DMG400006808 N 0.000
PGSC0003DMG400007112 Solanum tuberosum PGSC0003DMG400007112 N 0.000
PGSC0003DMG400030803 Solanum tuberosum PGSC0003DMG400030803 N 0.000
PK05257.1 Cannabis sativa PK05257.1 N 0.000
Pm001374 Prunus mume Pm001374 N 0.000
POPTR_0001s27490 Populus trichocarpa POPTR_0001s27490 N 0.000
POPTR_0002s09840 Populus trichocarpa POPTR_0002s09840 N 0.000
POPTR_0004s19460 Populus trichocarpa POPTR_0004s19460 N 0.000
POPTR_0009s06700 Populus trichocarpa POPTR_0009s06700 N 0.000
POPTR_0009s14590 Populus trichocarpa POPTR_0009s14590 N 0.000
PRUPE_ppa023619mg Prunus persica PRUPE_ppa023619mg N 0.000
SapurV1A.0027s0280 Salix purpurea SapurV1A.0027s0280 N 0.000
SapurV1A.0080s0360 Salix purpurea SapurV1A.0080s0360 N 0.000
SapurV1A.0219s0040 Salix purpurea SapurV1A.0219s0040 N 0.000
Sb02g028220 Sorghum bicolor Sb02g028220 N 0.000
Sb07g028010 Sorghum bicolor Sb07g028010 N 0.000
Si013819m.g Setaria italica Si013819m.g N 0.000
Si029897m.g Setaria italica Si029897m.g N 0.000
Solyc01g087050.2 Solanum lycopersicum Solyc01g087050.2 N 0.000
Solyc04g074320.1 Solanum lycopersicum Solyc04g074320.1 N 0.000
TCM_005892 Theobroma cacao TCM_005892 N 0.000
TCM_034881 Theobroma cacao TCM_034881 N 0.000
TCM_041441 Theobroma cacao TCM_041441 N 0.000
Thhalv10008125m.g Eutrema salsugineum Thhalv10008125m.g N 0.000
Traes_5BL_6888AE9CB Triticum aestivum Traes_5BL_6888AE9CB N 0.000
Traes_5DL_51643AC9F Triticum aestivum Traes_5DL_51643AC9F N 0.000
Traes_7AS_8054DC45D Triticum aestivum Traes_7AS_8054DC45D N 0.000
TRIUR3_30490 Triticum urartu TRIUR3_30490 N 0.000
DOT5 Vitis vinifera VIT_01s0011g03100 N 0.000
WIP3 Vitis vinifera VIT_06s0080g00270 N 0.000
TT1 Vitis vinifera VIT_18s0001g05860 N 0.000