CXXC1 (Homo sapiens)
CxxC

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF02008 (zf-CXXC) IPR002857 ENSG00000154832 T167985_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
This gene encodes a protein that functions as a transcriptional activator that binds specifically to non-methylated CpG motifs through its CXXC domain. The protein is a component of the SETD1 complex, regulates gene expression and is essential for vertebrate development. [provided by RefSeq, Sep 2015]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
CXXC1
M10428_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$CGBP_01
(Direct) (Direct)
CXXC1
M10429_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$CGBP_02
(Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
BAD93120.1_CONSTRUCT
M01919_2.00
PBM CONSTRUCTS
NNNBCGN

NCGVNNN
PBM
Weirauch et al.(2014)
pTH7032
1.000 1.000
For this family, TFs with SR scores > 0.700 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000285106 CxxC 160 208
ENSP00000390475 CxxC 160 208
ENSP00000465284 CxxC 160 208
ENSP00000465849 CxxC 8 56
ENSP00000467634 CxxC 160 208
ENSP00000468038 CxxC 160 208

Links

Other CxxC family TFs
Other Homo sapiens TFs

80 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action