CXXC5 (Homo sapiens)
CxxC

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF02008 (zf-CXXC) IPR002857 ENSG00000171604 T167987_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
The protein encoded by this gene is a retinoid-inducible nuclear protein containing a CXXC-type zinc finger motif. The encoded protein is involved in myelopoiesis, is required for DNA damage-induced p53 activation, regulates the differentiation of C2C12 myoblasts into myocytes, and negatively regulates cutaneous wound healing. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Nov 2015]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
CXXC5
M01210_2.00
Homo sapiens
NNNDCKNN

NNMGHNNN
PBM
Lambert et al.(2019)
pTH11216
(Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
For this family, TFs with SR scores > 0.700 will likely have a similar motif

Experimental Constructs

Motif ID Domain From To Sequence
M01210_2.00 CxxC 51 92

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000302543 CxxC 255 296
ENSP00000427379 CxxC 255 296

Links

Other CxxC family TFs
Other Homo sapiens TFs

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131 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action