Tet1 (Rattus norvegicus)
CxxC

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF02008 (zf-CXXC) IPR002857 ENSRNOG00000000277 T168286_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Predicted to enable methyl-CpG binding activity; methylcytosine dioxygenase activity; and transition metal ion binding activity. Predicted to be involved in several processes, including DNA demethylation; dendrite morphogenesis; and positive regulation of macromolecule metabolic process. Predicted to act upstream of or within inner cell mass cell differentiation; regulation of DNA methylation; and regulation of genetic imprinting. Predicted to be active in nucleus. Orthologous to human TET1 (tet methylcytosine dioxygenase 1). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
TET1
M01914_2.00 		Homo sapiens
NNHVCGHNN
NNDCGBDNN		 PBM
Weirauch et al.(2014)
pTH9605 		0.881 0.881
XP_001368961.2
M01917_2.00 		Monodelphis domestica
SSGGGGGV
BCCCCCSS		 PBM
Weirauch et al.(2014)
pTH9485 		0.738 0.738
For this family, TFs with SR scores > 0.700 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSRNOP00000000302 CxxC 563 604
ENSRNOP00000054747 CxxC 563 604

Links

Other CxxC family TFs
Other Rattus norvegicus TFs

Invalid Input OrderBy

38 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action