TF Information

Kdm2a *(Rattus norvegicus)* CxxC
Pfam ID	Interpro ID	Gene ID	CIS-BP ID	Sequence source	Animal TF db
PF02008 (zf-CXXC)	IPR002857	ENSRNOG00000019145	T168292_2.00	Ensembl (2018-Dec-8)	Link out
NCBI Gene Info: Predicted to enable several functions, including histone H3-methyl-lysine-36 demethylase activity; unmethylated CpG binding activity; and zinc ion binding activity. Predicted to be involved in several processes, including double-strand break repair via nonhomologous end joining; protein demethylation; and regulation of gene expression. Predicted to act upstream of or within several processes, including chordate embryonic development; heart looping; and positive regulation of macromolecule metabolic process. Predicted to be located in chromatin and nucleoplasm. Human ortholog(s) of this gene implicated in lung non-small cell carcinoma. Orthologous to human KDM2A (lysine demethylase 2A). [provided by Alliance of Genome Resources, Apr 2022]
Directly determined binding motifs
Name/Motif ID	Species	Forward	Reverse	Type/Study/Study ID	SR Score	DBD Identity
No direct experiments
Motifs from related TFs
Name/Motif ID	Species	Forward	Reverse	Type/Study/Study ID	SR Score	DBD Identity
KDM2A M01915_2.00	Meleagris gallopavo	NNNNYRNNNN	NNNNYRNNNN	PBM Weirauch et al.(2014) pTH9212	0.936	0.936
kdm2ba M01909_2.00	Danio rerio	NNNNCGN	NCGNNNN	PBM Weirauch et al.(2014) pTH8577	0.809	0.809
KDM2B M01911_2.00	Homo sapiens	NNNNNNCGN	NCGNNNNNN	PBM Weirauch et al.(2014) pTH9191	0.787	0.787
FBXL19 M01916_2.00	Tetraodon nigroviridis	NNNNCGNN	NNCGNNNN	PBM Weirauch et al.(2014) pTH8570	0.787	0.787
A6H8I1_DANRE M01906_2.00	Danio rerio	CGTACGYA	TRCGTACG	PBM Weirauch et al.(2014) pTH9257	0.745	0.745
kdm2aa M01910_2.00	Danio rerio	NCGNNNNNN	NNNNNNCGN	PBM Weirauch et al.(2014) pTH8585	0.702	0.702
For this family, TFs with SR scores > 0.700* will likely have a similar motif*