CIS-BP Database: Catalog of Inferred Sequence Binding Preferences
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Kdm2b
(
Rattus norvegicus
)
CxxC
TF Information
Pfam ID
Interpro ID
Gene ID
CIS-BP ID
Sequence source
Animal TF db
PF02008 (zf-CXXC)
IPR002857
ENSRNOG00000025702
T168293_2.00
Ensembl (2018-Dec-8)
Link out
NCBI Gene Info:
Predicted to enable several functions, including histone H3-methyl-lysine-36 demethylase activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in several processes, including brain development; cellular protein modification process; and embryonic morphogenesis. Predicted to act upstream of or within several processes, including histone H3-K36 demethylation; negative regulation of transcription by RNA polymerase II; and positive regulation of stem cell population maintenance. Predicted to be located in nucleus. Predicted to be part of PcG protein complex. Orthologous to human KDM2B (lysine demethylase 2B). [provided by Alliance of Genome Resources, Apr 2022]
Directly determined binding motifs
Name/Motif ID
Species
Forward
Reverse
Type/Study/Study ID
SR
Score
DBD
Identity
No direct experiments
Motifs from related TFs
Name/Motif ID
Species
Forward
Reverse
Type/Study/Study ID
SR
Score
DBD
Identity
KDM2B
M01911_2.00
Homo sapiens
NNNNNNCGN
NCGNNNNNN
PBM
Weirauch et al.(2014)
pTH9191
1.000
1.000
kdm2ba
M01909_2.00
Danio rerio
NNNNCGN
NCGNNNN
PBM
Weirauch et al.(2014)
pTH8577
0.979
0.979
FBXL19
M01916_2.00
Tetraodon nigroviridis
NNNNCGNN
NNCGNNNN
PBM
Weirauch et al.(2014)
pTH8570
0.894
0.894
A6H8I1_DANRE
M01906_2.00
Danio rerio
CGTACGYA
TRCGTACG
PBM
Weirauch et al.(2014)
pTH9257
0.851
0.851
KDM2A
M01915_2.00
Meleagris gallopavo
NNNNYRNNNN
NNNNYRNNNN
PBM
Weirauch et al.(2014)
pTH9212
0.809
0.809
BGIBMGA012843
M01907_2.00
Bombyx mori
NNCGCGTANVNN
NNBNTACGCGNN
PBM
Weirauch et al.(2014)
pTH9239
0.766
0.766
kdm2aa
M01910_2.00
Danio rerio
NCGNNNNNN
NNNNNNCGN
PBM
Weirauch et al.(2014)
pTH8585
0.723
0.723
For this family, TFs with SR scores >
0.700
will likely have a similar motif
DNA Binding Domains
Protein ID
Domain
From
To
Sequence
ENSRNOP00000050408
CxxC
347
393
GARRRRTRCRKCEACLRTECGECHFCKDMKKFGGPGRMKQSCIMRQC
Links
Other
CxxC
family TFs
Other
Rattus norvegicus
TFs
248 Related TFs
Name
Species
Gene ID
Motif Evidence
SR
Score
Action
Invalid Input OrderBy