XP_006525770.1 (Mus musculus)
CxxC

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF02008 (zf-CXXC) IPR002857 XP_006525770.1 T168544_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Enables DNA binding activity. Predicted to be involved in negative regulation of astrocyte differentiation and negative regulation of gene expression. Located in cytoplasm; heterochromatin; and nuclear lumen. Is expressed in several structures, including central nervous system; early conceptus; genitourinary system; and retina. Human ortholog(s) of this gene implicated in lung cancer. Orthologous to human MBD1 (methyl-CpG binding domain protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
XP_006525770.1
M01918_2.00		 Mus musculus
CGCGCGWT
AWCGCGCG		 PBM
Weirauch et al.(2014)
pTH7030		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
For this family, TFs with SR scores > 0.700 will likely have a similar motif

Experimental Constructs

Motif ID Domain From To Sequence
M01918_2.00 CxxC 27 74

DNA Binding Domains

Protein ID Domain From To Sequence
XP_006525770.1 CxxC 313 360

Links

Other CxxC family TFs
Other Mus musculus TFs

Invalid Input OrderBy

3 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action