dmd-3 (Caenorhabditis elegans)
DM

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00751 (DM) IPR001275 WBGene00012832 T169436_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including nematode male tail tip morphogenesis; neuron differentiation; and positive regulation of nematode male tail tip morphogenesis. Acts upstream of or within positive regulation of transcription by RNA polymerase II. Located in neuronal cell body. Is expressed in several structures, including PHC; epithelial cell; gonad; ray neuron type A; and tail hypodermis. Orthologous to human DMRT2 (doublesex and mab-3 related transcription factor 2). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
dmd-3
M00658_2.00		 Caenorhabditis elegans
NNWGTWDN
NHWACWNN		 PBM
Narasimhan et al.(2015)
pTH10638		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
CBG09413
M01924_2.00 		Caenorhabditis briggsae
AATGTTTC
GAAACATT		 PBM
Weirauch et al.(2014)
pTH8330 		0.918 0.745
WUBG_11979
M01922_2.00 		Wuchereria bancrofti
ATGTWTCA
TGAWACAT		 PBM
Weirauch et al.(2014)
pTH9296 		0.917 0.766
Bm2567
M01923_2.00 		Brugia malayi
NNNWGTTKHN
NDMAACWNNN		 PBM
Weirauch et al.(2014)
pTH9246 		0.914 0.766
dmd-10
M00657_2.00 		Caenorhabditis elegans
AWTGTTTC
GAAACAWT		 PBM
Narasimhan et al.(2015)
pTH9142 		0.914 0.745
CBN06605
M01925_2.00 		Caenorhabditis brenneri
NWGTWKN
NMWACWN		 PBM
Weirauch et al.(2014)
pTH9247 		0.909 0.745
CJA05633_CONSTRUCT
M01936_2.00 		PBM CONSTRUCTS
NWGTWDN
NHWACWN		 PBM
Weirauch et al.(2014)
pTH9344 		0.909 0.745
For this family, TFs with SR scores > 0.845 will likely have a similar motif

Experimental Constructs

Motif ID Domain From To Sequence
M00658_2.00 DM 19 65

DNA Binding Domains

Protein ID Domain From To Sequence
Y43F8C.10a DM 15 60
Y43F8C.10a DM 113 159
Y43F8C.10b DM 19 65

Links

Other DM family TFs
Other Caenorhabditis elegans TFs

Invalid Input OrderBy

73 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action