MDP0000258338 (Malus domestica)
E2F

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source
PF02319 (E2F_TDP) IPR003316 MDP0000258338 T173978_2.00 JGI:Phytozome (2018-Apr-12)

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
E2FC
M06870_2.00 		Arabidopsis thaliana
AWDDDGGCGCCAAAR
YTTTGGCGCCHHHWT		 Dap-seq
OMalley et al.(2016)
E2FC_col_a 		0.453 0.453
E2F4
M02961_2.00 		Homo sapiens
AATGGCGCCAAA
TTTGGCGCCATT		 SELEX
Jolma et al.(2013)
E2F4_1 		0.438 0.438
E2F4
M02962_2.00 		Homo sapiens
TTTGGCGCCAAA
TTTGGCGCCAAA		 SELEX
Jolma et al.(2013)
E2F4_2 		0.438 0.438
E2F4
M04707_2.00 		Homo sapiens
NWWKGGCGCCAAAW
WTTTGGCGCCMWWN		 SELEX
Yin et al.(2017)
E2F4_eDBD_HT-SELEX 		0.438 0.438
E2F4
M08109_2.00 		Homo sapiens
NSGCGGGARVN
NBYTCCCGCSN		 ChIP-seq
Mathelier et al.(2014)
MA0470.1 		0.438 0.438
E2F4
M07942_2.00 		Homo sapiens
SGCGSGARDNNBNVN
NBNVNNHYTCSCGCS		 ChIP-seq
Gerstein et al.(2012)
HeLa-S3_E2F4_UCD 		0.438 0.438
E2F4
M07943_2.00 		Homo sapiens
SGCGGGARDNNBVVN
NBBVNNHYTCCCGCS		 ChIP-seq
Gerstein et al.(2012)
K562b_E2F4_UCD 		0.438 0.438
E2F4
M09036_2.00 		Homo sapiens
VDRGGCGGGRVND
HNBYCCCGCCYHB		 Misc
Kulakovskiy et al.(2013)
E2F4_HUMAN.H11MO.0.A 		0.438 0.438
E2f4
M09037_2.00 		Mus musculus
NRDDGGCGGGRMNN
NNKYCCCGCCHHYN		 Misc
Kulakovskiy et al.(2013)
E2F4_MOUSE.H11MO.0.A 		0.438 0.438
E2f5
M09042_2.00 		Mus musculus
NGCGCSAAAN
NTTTSGCGCN		 Misc
Kulakovskiy et al.(2013)
E2F5_MOUSE.H11MO.0.B 		0.438 0.438
E2F4
M09524_2.00 		Homo sapiens
VGCGSGAADH
DHTTCSCGCB		 Misc
Heinz et al.(2010)
K562-E2F4_GSE31477 		0.438 0.438
E2F4
M10457_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$E2F4_05 		0.438 0.438
E2F4
M10458_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$E2F4_Q3 		0.438 0.438
E2F4
M10459_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$E2F4_Q6 		0.438 0.438
For this family, TFs with SR scores > 0.429 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
MDP0000258338 E2F 9 77

Links

Other E2F family TFs
Other Malus domestica TFs

224 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
MDP0000311683 Malus domestica MDP0000311683 I 1.000
orange1.1g042344m.g Citrus sinensis orange1.1g042344m.g N 0.719
PDK_20s1507381g001 Phoenix dactylifera PDK_20s1507381g001 N 0.703
Traes_7AS_D5F5D49CA Triticum aestivum Traes_7AS_D5F5D49CA I 0.672
OMERI06G10800 Oryza meridionalis OMERI06G10800 I 0.672
OB06G18550 Oryza brachyantha OB06G18550 I 0.672
Traes_7DS_791693792 Triticum aestivum Traes_7DS_791693792 I 0.672
Traes_6AL_DD0E18465 Triticum aestivum Traes_6AL_DD0E18465 I 0.672
Pavir.Aa00738 Panicum virgatum Pavir.Aa00738 I 0.656
PK09429.1 Cannabis sativa PK09429.1 N 0.656
mg017600m Mimulus guttatus mg017600m N 0.625
mgf025923m Mimulus guttatus mgf025923m N 0.625
Lus10005840.g Linum usitatissimum Lus10005840.g N 0.606
E2FD Arabidopsis thaliana AT5G14960 D 0.594
MLOC_67050 Hordeum vulgare MLOC_67050 I 0.547
Pm003633 Prunus mume Pm003633 N 0.529
Ciclev10020979m.g Citrus clementina Ciclev10020979m.g I 0.517
PGSC0003DMG400001296 Solanum tuberosum PGSC0003DMG400001296 I 0.500
e2f8 Takifugu rubripes ENSTRUG00000015792 I 0.490
Pavir.Ab02967 Panicum virgatum Pavir.Ab02967 N 0.484
tetur01g05310 Tetranychus urticae tetur01g05310 I 0.469
NEMVEDRAFT_v1g222302 Nematostella vectensis NEMVEDRAFT_v1g222302 N 0.469
Cagra.1390s0037 Capsella grandiflora Cagra.1390s0037 I 0.466
ML000126a Mnemiopsis leidyi ML000126a I 0.462
Lus10033151.g Linum usitatissimum Lus10033151.g I 0.462
Tal_R001534 Tyto alba Tal_R001534 I 0.459
ENSAPLG00000005664 Anas platyrhynchos ENSAPLG00000005664 I 0.459
Afo_R001855 Aptenodytes forsteri Afo_R001855 I 0.459
Aan_R013725 Calypte anna Aan_R013725 I 0.459
ISCW000457 Ixodes scapularis ISCW000457 I 0.459
ENSSHAG00000011293 Sarcophilus harrisii ENSSHAG00000011293 I 0.459
ENSMEUG00000012534 Macropus eugenii ENSMEUG00000012534 I 0.459
E2F5 Meleagris gallopavo ENSMGAG00000011709 I 0.459
ENSPMAG00000000488 Petromyzon marinus ENSPMAG00000000488 I 0.459
POPTR_0006s22150 Populus trichocarpa POPTR_0006s22150 I 0.453
ENSNLEG00000002804 Nomascus leucogenys ENSNLEG00000002804 I 0.453
ATE2F2 Arabidopsis lyrata fgenesh1_pm.C_scaffold_1003009 I 0.453
Bostr.15654s0048 Boechera stricta Bostr.15654s0048 I 0.453
30170.m014171 Ricinus communis 30170.m014171 I 0.453
Carubv10009432m.g Capsella rubella Carubv10009432m.g I 0.453
SapurV1A.0510s0180 Salix purpurea SapurV1A.0510s0180 I 0.453
GLYMA04G02720 Glycine max GLYMA04G02720 I 0.453
Cagra.1843s0001 Capsella grandiflora Cagra.1843s0001 I 0.453
Aqu1.225581 Amphimedon queenslandica Aqu1.225581 I 0.453
tetur03g04940 Tetranychus urticae tetur03g04940 I 0.446
SMU15000713 Schmidtea mediterranea SMU15000713 I 0.446
tetur03g04810 Tetranychus urticae tetur03g04810 I 0.446
SapurV1A.1444s0050 Salix purpurea SapurV1A.1444s0050 I 0.446
SapurV1A.1401s0050 Salix purpurea SapurV1A.1401s0050 I 0.446
E2FC Arabidopsis thaliana AT1G47870 D 0.446
MDOA005480 Musca domestica MDOA005480 I 0.444
LCUP006273 Lucilia cuprina LCUP006273 I 0.444
e2f5 Tetraodon nigroviridis ENSTNIG00000002195 I 0.439
MCINX013437 Melitaea cinxia MCINX013437 I 0.438
e2f4 Tetraodon nigroviridis ENSTNIG00000005170 I 0.438
e2f5 Takifugu rubripes ENSTRUG00000002354 I 0.438
e2f4 Tetraodon nigroviridis ENSTNIG00000008814 I 0.438
e2f4 Takifugu rubripes ENSTRUG00000009757 I 0.438
HMEL002387 Heliconius melpomene HMEL002387 I 0.438
BGLB004502 Biomphalaria glabrata BGLB004502 I 0.438
HelroG191241 Helobdella robusta HelroG191241 I 0.438
ENSXMAG00000001974 Xiphophorus maculatus ENSXMAG00000001974 I 0.438
KGM_13816 Danaus plexippus KGM_13816 I 0.438
XP_002154174.1 Hydra magnipapillata XP_002154174.1 I 0.438
ENSTSYG00000007645 Tarsius syrichta ENSTSYG00000007645 I 0.438
e_gw1.2.455.1 Phytophthora capsici e_gw1.2.455.1 I 0.438
TriadG50818 Trichoplax adhaerens TriadG50818 I 0.438
Ocbimv22032616m.g Octopus bimaculoides Ocbimv22032616m.g I 0.438
Ocbimv22032617m.g Octopus bimaculoides Ocbimv22032617m.g I 0.438
HHAL003001-PA Halyomorpha halys HHAL003001-PA I 0.438
Pvit_14741 Pogona vitticeps Pvit_14741 I 0.438
Pvit_02135 Pogona vitticeps Pvit_02135 I 0.438
Sakowv30012530m.g Saccoglossus kowalevskii Sakowv30012530m.g I 0.438
Lus10016972.g Linum usitatissimum Lus10016972.g I 0.438
Pavir.J29330 Panicum virgatum Pavir.J29330 I 0.438
Pavir.Ga01887 Panicum virgatum Pavir.Ga01887 I 0.438
MDP0000268258 Malus domestica MDP0000268258 I 0.438
MDP0000250386 Malus domestica MDP0000250386 I 0.438
Pm006225 Prunus mume Pm006225 I 0.438
Myotis_brandtii_E2f4_10015050 Myotis brandtii Myotis_brandtii_E2f4_10015050 I 0.438
SINV22036 Solenopsis invicta SINV22036 I 0.438
e2f4.S Xenopus laevis XB-GENE-482725 I 0.438
ATE2F2 Populus trichocarpa POPTR_0002s02500 I 0.438
NV25797 Nasonia vitripennis NV25797 I 0.438
e2f4 Xenopus tropicalis XB-GENE-482721 I 0.438
E2F4 Taeniopygia guttata ENSTGUG00000005417 I 0.438
ENSP00000368686-D1 Bos grunniens ENSP00000368686-D1 I 0.438
ENSMMUP00000026667 Macaca fascicularis ENSMMUP00000026667 I 0.438
PK10965.1 Cannabis sativa PK10965.1 I 0.438
TTHERM_01099150 Tetrahymena thermophila TTHERM_01099150 I 0.438
NEMVEDRAFT_v1g235633 Nematostella vectensis NEMVEDRAFT_v1g235633 I 0.438
ASIM_0000394401 Anisakis simplex ASIM_0000394401 I 0.438
ENSFALG00000007077 Ficedula albicollis ENSFALG00000007077 I 0.438
E2F4 Felis catus ENSFCAG00000009268 I 0.438
E2F4 Homo sapiens ENSG00000205250 D 0.438
E2F4 Equus caballus ENSECAG00000015595 I 0.438
ENSDORG00000015131 Dipodomys ordii ENSDORG00000015131 I 0.438
e2f4 Danio rerio ENSDARG00000101578 I 0.438
SSLN_0001335001 Schistocephalus solidus SSLN_0001335001 I 0.438
E2F4 Dasypus novemcinctus ENSDNOG00000041139 I 0.438
e2f4 Gasterosteus aculeatus ENSGACG00000013827 I 0.438
E2F4 Gallus gallus ENSGALG00000001722 I 0.438
nAv.1.0.1.g08239 Acanthocheilonema viteae nAv.1.0.1.g08239 I 0.438
HNAJ_0000082301 Hymenolepis nana HNAJ_0000082301 I 0.438
E2F4 Meleagris gallopavo ENSMGAG00000002517 I 0.438
ENSSTOG00000016434 Ictidomys tridecemlineatus ENSSTOG00000016434 I 0.438
ENSGMOG00000012711 Gadus morhua ENSGMOG00000012711 I 0.438
nRc.2.0.1.g30898 Romanomermis culicivorax nRc.2.0.1.g30898 I 0.438
E2F4 Gorilla gorilla ENSGGOG00000011924 I 0.438
e2f5 Danio rerio ENSDARG00000038812 I 0.438
TASK_0000557201 Taenia asiatica TASK_0000557201 I 0.438
TsM_000874400 Taenia solium TsM_000874400 I 0.438
TCNE_0000648301 Toxocara canis TCNE_0000648301 I 0.438
EFV59050 Trichinella spiralis EFV59050 I 0.438
Bra002398 Brassica rapa Bra002398 I 0.438
Bo9g106030 Brassica oleracea Bo9g106030 I 0.438
ACEP12483 Atta cephalotes ACEP12483 I 0.438
BGIBMGA006899 Bombyx mori BGIBMGA006899 I 0.438
TTAC_0000774301 Hydatigera taeniaeformis TTAC_0000774301 I 0.438
E2F4 Anolis carolinensis ENSACAG00000028484 I 0.438
ENSAMEG00000017275 Ailuropoda melanoleuca ENSAMEG00000017275 I 0.438
ENSCJAG00000023311 Callithrix jacchus ENSCJAG00000023311 I 0.438
E2F4 Cavia porcellus ENSCPOG00000010845 I 0.438
ENSCSAG00000003814 Chlorocebus sabaeus ENSCSAG00000003814 I 0.438
E2F4 Callithrix jacchus ENSCJAG00000016403 I 0.438
e2f4/5 Ciona intestinalis ENSCING00000024912 I 0.438
E2F4 Bos taurus ENSBTAG00000012063 I 0.438
E2F4 Canis familiaris ENSCAFG00000020375 I 0.438
HmN_000089900 Hymenolepis microstoma HmN_000089900 I 0.438
nLs.2.1.2.g07942 Litomosoides sigmodontis nLs.2.1.2.g07942 I 0.438
E2F4 Procavia capensis ENSPCAG00000013266 I 0.438
ENSPFOG00000006707 Poecilia formosa ENSPFOG00000006707 I 0.438
ENSPMAG00000000860 Petromyzon marinus ENSPMAG00000000860 I 0.438
ENSPANG00000016794 Papio anubis ENSPANG00000016794 I 0.438
E2F4 Myotis lucifugus ENSMLUG00000023162 I 0.438
D917_10139 Trichinella nativa D917_10139 I 0.438
E2F4 Ochotona princeps ENSOPRG00000015165 I 0.438
ENSPPYG00000007445 Pongo abelii ENSPPYG00000007445 I 0.438
ASU_07245 Ascaris suum ASU_07245 I 0.438
E2f4 Rattus norvegicus ENSRNOG00000015708 I 0.438
E2F4 Sus scrofa ENSSSCG00000002787 I 0.438
SapurV1A.0025s0470 Salix purpurea SapurV1A.0025s0470 I 0.438
E2f5 Rattus norvegicus ENSRNOG00000010760 I 0.438
E2F5 Pteropus vampyrus ENSPVAG00000013659 I 0.438
E2F4 Pan troglodytes ENSPTRG00000031180 I 0.438
E2F4 Pteropus vampyrus ENSPVAG00000005274 I 0.438
ENSONIG00000010271 Oreochromis niloticus ENSONIG00000010271 I 0.438
e2f4 Oryzias latipes ENSORLG00000015705 I 0.438
EmuJ_000535700 Echinococcus multilocularis EmuJ_000535700 I 0.438
E2F4 Macaca mulatta ENSMMUG00000020258 I 0.438
E2f4 Mus musculus ENSMUSG00000014859 D 0.438
ENSNLEG00000004342 Nomascus leucogenys ENSNLEG00000004342 I 0.438
HDID_0000938401 Hymenolepis diminuta HDID_0000938401 I 0.438
E2F4 Monodelphis domestica ENSMODG00000006150 I 0.438
E2F4 Otolemur garnettii ENSOGAG00000000010 I 0.438
ECANG7_01951 Echinococcus canadensis ECANG7_01951 I 0.438
ENSMPUG00000005564 Mustela putorius furo ENSMPUG00000005564 I 0.438
E2F5 Bos taurus ENSBTAG00000009378 I 0.436
E2F5 Callithrix jacchus ENSCJAG00000000387 I 0.436
E2F5 Canis familiaris ENSCAFG00000008628 I 0.436
ENSMMUP00000008413 Macaca fascicularis ENSMMUP00000008413 I 0.436
ENSSTOG00000013339 Ictidomys tridecemlineatus ENSSTOG00000013339 I 0.436
OBART04G12180 Oryza barthii OBART04G12180 I 0.436
ENSSHAG00000011240 Sarcophilus harrisii ENSSHAG00000011240 I 0.436
augustus_masked-nMf.1.1.scaf26567-processed-gene-0.0 Meloidogyne floridensis augustus_masked-nMf.1.1.scaf26567-processed-gene-0.0 I 0.432
augustus_masked-nMf.1.1.scaf34489-processed-gene-0.0 Meloidogyne floridensis augustus_masked-nMf.1.1.scaf34489-processed-gene-0.0 I 0.432
A_00357 Schistosoma haematobium A_00357 I 0.431
e2f5 Xenopus tropicalis XB-GENE-481326 I 0.431
ECPE_0001328101 Echinostoma caproni ECPE_0001328101 I 0.431
OFLC_0000044701 Onchocerca flexuosa OFLC_0000044701 I 0.431
SCUD_0001228801 Schistosoma curassoni SCUD_0001228801 I 0.431
DME_0000040101 Dracunculus medinensis DME_0000040101 I 0.431
BTMF_0000949601 Brugia timori BTMF_0000949601 I 0.431
T265_09252 Opisthorchis viverrini T265_09252 I 0.431
Sjc_0105380 Schistosoma japonicum Sjc_0105380 I 0.431
nOo.2.0.1.g03631 Onchocerca ochengi nOo.2.0.1.g03631 I 0.431
SROB_0001283101 Schistosoma rodhaini SROB_0001283101 I 0.431
TCLT_0000777801 Thelazia callipaeda TCLT_0000777801 I 0.431
LotgiG127203 Lottia gigantea LotgiG127203 I 0.431
E2F5 Macaca mulatta ENSMMUG00000006380 I 0.431
ENSLOCG00000006277 Lepisosteus oculatus ENSLOCG00000006277 I 0.431
E2F5 Loxodonta africana ENSLAFG00000006007 I 0.431
ENSLACG00000004024 Latimeria chalumnae ENSLACG00000004024 I 0.431
E2F5 Monodelphis domestica ENSMODG00000005958 I 0.431
E2f5 Mus musculus ENSMUSG00000027552 D 0.431
E2F5 Ochotona princeps ENSOPRG00000013545 I 0.431
E2F5 Otolemur garnettii ENSOGAG00000013117 I 0.431
E2F5 Oryctolagus cuniculus ENSOCUG00000012890 I 0.431
E2F5 Gorilla gorilla ENSGGOG00000009737 I 0.431
ENSGALG00000015818 Gallus gallus ENSGALG00000015818 I 0.431
ENSAMEG00000002392 Ailuropoda melanoleuca ENSAMEG00000002392 I 0.431
DAPPUDRAFT_303685 Daphnia pulex DAPPUDRAFT_303685 I 0.431
CapteG1695 Capitella teleta CapteG1695 I 0.431
Bm7213 Brugia malayi Bm7213 I 0.431
ENSCSAG00000013198 Chlorocebus sabaeus ENSCSAG00000013198 I 0.431
ENSCSAVG00000000261 Ciona savignyi ENSCSAVG00000000261 I 0.431
E2F5 Homo sapiens ENSG00000133740 D 0.431
E2F5 Felis catus ENSFCAG00000018498 I 0.431
E2F5 Dasypus novemcinctus ENSDNOG00000009802 I 0.431
mgf019070m Mimulus guttatus mgf019070m I 0.431
ENSPANG00000014637 Papio anubis ENSPANG00000014637 I 0.431
Ca_04894 Cicer arietinum Ca_04894 I 0.431
WBGene00243491 Onchocerca volvulus WBGene00243491 I 0.431
TCM_046885 Theobroma cacao TCM_046885 I 0.431
SPU_028827 Strongylocentrotus purpuratus SPU_028827 I 0.431
Cflo_07334--XP_624285.1_APIME Camponotus floridanus Cflo_07334--XP_624285.1_APIME I 0.431
Hsal_12430--XP_624285.1_APIME Harpegnathos saltator Hsal_12430--XP_624285.1_APIME I 0.431
fgenesh2_pm.scaffold_6000024 Branchiostoma floridae fgenesh2_pm.scaffold_6000024 I 0.431
fgenesh2_pg.scaffold_349000085 Branchiostoma floridae fgenesh2_pg.scaffold_349000085 I 0.431
cassava4389.m1 Manihot esculenta cassava4389.m1 I 0.431
Smp_093310 Schistosoma mansoni Smp_093310 I 0.431
PRUPE_ppa024272mg Prunus persica PRUPE_ppa024272mg I 0.431
E2F5 Pan troglodytes ENSPTRG00000020384 I 0.431
GLYMA06G02738 Glycine max GLYMA06G02738 I 0.431
GB53826 Apis mellifera GB53826 I 0.431
ENSPFOG00000022062 Poecilia formosa ENSPFOG00000022062 I 0.431
L798_07726 Zootermopsis nevadensis L798_07726 I 0.431
WUBG_10257 Wuchereria bancrofti WUBG_10257 I 0.431
LOAG_00035 Loa loa LOAG_00035 I 0.431
E2F5 Sus scrofa ENSSSCG00000006145 I 0.431
E2F4 Microcebus murinus ENSMICG00000007744 I 0.429
ENSETEG00000016857 Echinops telfairi ENSETEG00000016857 I 0.429
E2F5 Procavia capensis ENSPCAG00000014594 I 0.429
E2F5 Tursiops truncatus ENSTTRG00000012129 I 0.429