CIS-BP Database: Catalog of Inferred Sequence Binding Preferences
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EBF2
(
Homo sapiens
)
EBF1
TF Information
Pfam ID
Interpro ID
Gene ID
CIS-BP ID
Sequence source
Animal TF db
PF16422 (COE1_DBD)
(none)
ENSG00000221818
T174554_2.00
Ensembl (2018-Dec-8)
Link out
NCBI Gene Info:
The protein encoded by this gene belongs to the COE (Collier/Olf/EBF) family of non-basic, helix-loop-helix transcription factors that have a well conserved DNA binding domain. The COE family proteins play an important role in variety of developmental processes. Studies in mouse suggest that this gene may be involved in the differentiation of osteoblasts. [provided by RefSeq, Oct 2011]
Directly determined binding motifs
Name/Motif ID
Species
Forward
Reverse
Type/Study/Study ID
SR
Score
DBD
Identity
EBF2
M10466_2.00
Homo sapiens
Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$COE2_02
(Direct)
(Direct)
Motifs from related TFs
Name/Motif ID
Species
Forward
Reverse
Type/Study/Study ID
SR
Score
DBD
Identity
Ebf2
M10467_2.00
Mus musculus
Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$COE2_01
1.000
1.000
EBF3
M10461_2.00
Homo sapiens
Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$EBF_Q6
0.887
0.887
Ebf1
M09045_2.00
Mus musculus
DBYCCCWRGGGAV
BTCCCYWGGGRVH
Misc
Kulakovskiy et al.(2013)
COE1_MOUSE.H11MO.0.A
0.959
0.959
Ebf1
M09527_2.00
Mus musculus
DBTCCCHDGGGA
TCCCHDGGGAVH
Misc
Heinz et al.(2010)
proBcell-EBF_GSE21978
0.959
0.959
Ebf1
M10469_2.00
Mus musculus
VYMHVYYCYYBRGGGAVTHKHB
VDMDABTCCCYVRRGRRBDKRB
Transfac
Matys et al.(2006)
V$OLF1_01
0.857
0.857
EBF4
M10460_2.00
Homo sapiens
Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$EBF4_02
0.827
0.827
Ebf4
M10468_2.00
Mus musculus
Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$EBF4_01
0.939
0.939
kn
M03721_2.00
Drosophila melanogaster
BWATTCCCHDGGGAATWV
BWATTCCCHDGGGAATWV
SELEX
Nitta et al.(2015)
kn_1
0.727
0.727
For this family, TFs with SR scores >
0.700
will likely have a similar motif
DNA Binding Domains
Protein ID
Domain
From
To
Sequence
ENSP00000386178
EBF1
1
98
MCRVLLTHEVMCSRCCEKKSCGNRNETPSDPVIIDRFFLKFFLKCNQNCLKTAGNPRDMRRFQVVLSTTVNVDGHVLAVSDNMFVHNNSKHGRRARRL
ENSP00000430241
EBF1
16
246
EKSLGAEMDSVRSWVRNVGVVDANVAAQSGVALSRAHFEKQPPSNLRKSNFFHFVLALYDRQGQPVEIERTAFVDFVENDKEQGNEKTNNGTHYKLQLLYSNGVRTEQDLYVRLIDSVTKQPIAYEGQNKNPEMCRVLLTHEVMCSRCCEKKSCGNRNETPSDPVIIDRFFLKFFLKCNQNCLKTAGNPRDMRRFQVVLSTTVNVDGHVLAVSDNMFVHNNSKHGRRARRL
Links
Other
EBF1
family TFs
Other
Homo sapiens
TFs
367 Related TFs
Name
Species
Gene ID
Motif Evidence
SR
Score
Action
Invalid Input OrderBy