TF Information

ENSP00000227163 *(Macaca fascicularis)* Ets
Pfam ID	Interpro ID	Gene ID	CIS-BP ID	Sequence source
PF00178 (Ets)	IPR000418	ENSP00000227163	T177769_2.00	GigaDB (2015-Oct-22)
NCBI Gene Info: This gene encodes an ETS-domain transcription factor that activates gene expression during myeloid and B-lymphoid cell development. The nuclear protein binds to a purine-rich sequence known as the PU-box found near the promoters of target genes, and regulates their expression in coordination with other transcription factors and cofactors. The protein can also regulate alternative splicing of target genes. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Directly determined binding motifs
Name/Motif ID	Species	Forward	Reverse	Type/Study/Study ID	SR Score	DBD Identity
No direct experiments
Motifs from related TFs
Name/Motif ID	Species	Forward	Reverse	Type/Study/Study ID	SR Score	DBD Identity
Spi1 M00155_2.00	Mus musculus	NNNVGGAAVH	DBTTCCBNNN	PBM Badis et al.(2009) Sfpi1_1034	0.866	0.917
Spi1 M01475_2.00	Mus musculus	DDNVGGAASY	RSTTCCBNHH	PBM Wei et al.(2010) Sfpi1	0.866	0.917
SPI1 M02965_2.00	Homo sapiens	RAAAAGMGGAAGTW	WACTTCCKCTTTTY	SELEX Jolma et al.(2013) SPI1_1	0.866	0.917
SPI1 M07944_2.00	Homo sapiens	NRAAWGRGGAASTGRRANN	NNTYYCASTTCCYCWTTYN	ChIP-seq Gerstein et al.(2012) GM12878_PU1_HudsonAlpha	0.866	0.917
SPI1 M07945_2.00	Homo sapiens	AAWGRGGAASTGARAVHNN	NNDBTYTCASTTCCYCWTT	ChIP-seq Gerstein et al.(2012) GM12891_PU1_HudsonAlpha	0.866	0.917
SPI1 M07946_2.00	Homo sapiens	RRAAAGAGGAAGTGV	BCACTTCCTCTTTYY	ChIP-seq Gerstein et al.(2012) K562_PU1_HudsonAlpha	0.866	0.917
SPI1 M08026_2.00	Homo sapiens	VRAAWGRGGAAGTGV	BCACTTCCYCWTTYB	ChIP-seq Chen et al.(2011) SRP005406_SPI1	0.866	0.917
Spi1 M08027_2.00	Mus musculus	VRRAWRRGGAAGWVD	HBWCTTCCYYWTYYB	ChIP-seq Chen et al.(2011) GSE11329_Sfpi1	0.866	0.917
SPI1 M09047_2.00	Homo sapiens	VRAAWGRGGAAGTGRNN	NNYCACTTCCYCWTTYB	Misc Kulakovskiy et al.(2013) SPI1_HUMAN.H11MO.0.A	0.866	0.917
Spi1 M09065_2.00	Mus musculus	VRARWGRGGAAGTGV	BCACTTCCYCWYTYB	Misc Kulakovskiy et al.(2013) SPI1_MOUSE.H11MO.0.A	0.866	0.917
Spi1 M09538_2.00	Mus musculus	WGAGGAAGTG	CACTTCCTCW	Misc Heinz et al.(2010) ThioMac-PU.1_GSE21512	0.866	0.917
SPI1 M10472_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$PU1_Q4	0.866	0.917
SPI1 M10473_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$PU1_Q6	0.866	0.917
SPI1 M10474_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$SPI1_01	0.866	0.917
SPI1 M10475_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$SPI1_07	0.866	0.917
SPI1 M10476_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$SPI1_08	0.866	0.917
SPI1 M10477_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$SPI1_Q5	0.866	0.917
For this family, TFs with SR scores > 0.717* will likely have a similar motif*