Foxm1 (Mus musculus)
Forkhead

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00250 (Forkhead) IPR001766 ENSMUSG00000001517 T186340_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Enables transcription cis-regulatory region binding activity. Involved in DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator; positive regulation of double-strand break repair; and positive regulation of transcription, DNA-templated. Acts upstream of or within several processes, including liver development; positive regulation of transcription by RNA polymerase II; and vasculogenesis. Located in nucleus. Is expressed in several structures, including alimentary system; brain; genitourinary system; respiratory system; and sensory organ. Used to study hepatocellular carcinoma; lung cancer; and type 2 diabetes mellitus. Orthologous to human FOXM1 (forkhead box M1). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Foxm1
M01009_2.00		 Mus musculus
NNYDWYNN
NNRWHRNN		 PBM
Nakagawa et al.(2013)
Foxm1		 (Direct) (Direct)
Foxm1
M09099_2.00		 Mus musculus
NVWRDGYAAAYA
TRTTTRCHYWBN		 Misc
Kulakovskiy et al.(2013)
FOXM1_MOUSE.H11MO.0.B		 (Direct) (Direct)
Foxm1
M10568_2.00		 Mus musculus Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$FOXM1_03		 (Direct) (Direct)
Foxm1
M10569_2.00		 Mus musculus Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$FOXM1_04		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
FOXM1
M09085_2.00 		Homo sapiens
NVWRDGYAAAYA
TRTTTRCHYWBN		 Misc
Kulakovskiy et al.(2013)
FOXM1_HUMAN.H11MO.0.A 		0.829 1.000
FOXM1
M10532_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$FOXM1_01 		0.829 1.000
FOXM1
M10533_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$FOXM1_Q3_02 		0.829 1.000
FOXM1
M10534_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$FOXM1_Q3 		0.829 1.000
FOXM1
M10535_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$FOXM1_Q6 		0.829 1.000
FOXM1
M01979_2.00 		Meleagris gallopavo
RDAWRCAH
DTGYWTHY		 PBM
Weirauch et al.(2014)
pTH8652 		0.821 0.952
For this family, TFs with SR scores > 0.664 will likely have a similar motif

Experimental Constructs

Motif ID Domain From To Sequence
M01009_2.00 Forkhead 16 102

DNA Binding Domains

Protein ID Domain From To Sequence
ENSMUSP00000073041 Forkhead 234 320
ENSMUSP00000107776 Forkhead 234 321

Links

Other Forkhead family TFs
Other Mus musculus TFs

Invalid Input OrderBy

65 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action