Foxn4 (Mus musculus)
Forkhead

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00250 (Forkhead) IPR001766 ENSMUSG00000042002 T186359_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Enables DNA-binding transcription factor activity, RNA polymerase II-specific; chromatin binding activity; and cis-regulatory region sequence-specific DNA binding activity. Involved in neural retina development; positive regulation of transcription by RNA polymerase II; and ventral spinal cord interneuron fate commitment. Acts upstream of or within neuron fate commitment. Located in nucleus. Is expressed in several structures, including alimentary system; central nervous system; eye; metanephros; and respiratory system. Orthologous to human FOXN4 (forkhead box N4). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Foxn4
M01011_2.00		 Mus musculus
NNNVACGCNN
NNGCGTBNNN		 PBM
Nakagawa et al.(2013)
Foxn4		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
FOXN1
M10531_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$WHN_B 		0.798 0.895
Foxn1
M01010_2.00 		Mus musculus
NAHRCNNNNN
NNNNNGYDTN		 PBM
Nakagawa et al.(2013)
Foxn1 		0.798 0.884
jumu
M01012_2.00 		Drosophila melanogaster
NNNNVACGCN
NGCGTBNNNN		 PBM
Nakagawa et al.(2013)
Jumeau 		0.777 0.733
For this family, TFs with SR scores > 0.664 will likely have a similar motif

Experimental Constructs

Motif ID Domain From To Sequence
M01011_2.00 Forkhead 16 106

DNA Binding Domains

Protein ID Domain From To Sequence
ENSMUSP00000047951 Forkhead 197 287

Links

Other Forkhead family TFs
Other Mus musculus TFs

Invalid Input OrderBy

198 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action