Foxp2 (Rattus norvegicus)
Forkhead

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00250 (Forkhead) IPR001766 ENSRNOG00000054508 T187003_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Enables androgen receptor binding activity. Involved in forebrain development; innate vocalization behavior; and response to testosterone. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in several diseases, including attention deficit hyperactivity disorder; autism spectrum disorder (multiple); communication disorder (multiple); dyslexia; and major depressive disorder. Orthologous to human FOXP2 (forkhead box P2). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Foxp2
M00792_2.00 		Mus musculus
RTAAACAD
HTGTTTAY		 PBM
Weirauch et al.(2013)
pTH1288 		0.829 1.000
FOXP2
M05866_2.00 		Homo sapiens
RTAAAYAWNN
NNWTRTTTAY		 SMiLE-seq
Isakova et al.(2017)
FOXP2 		0.829 1.000
FOXP2
M08116_2.00 		Homo sapiens
NDGTAAACAVN
NBTGTTTACHN		 ChIP-seq
Mathelier et al.(2014)
MA0593.1 		0.829 1.000
FOXP2
M09089_2.00 		Homo sapiens
DGTAAACAV
BTGTTTACH		 Misc
Kulakovskiy et al.(2013)
FOXP2_HUMAN.H11MO.0.C 		0.829 1.000
Foxp2
M09101_2.00 		Mus musculus
NGTAAACAN
NTGTTTACN		 Misc
Kulakovskiy et al.(2013)
FOXP2_MOUSE.H11MO.0.A 		0.829 1.000
FOXP1
M00836_2.00 		Homo sapiens
NRTMAACANN
NNTGTTKAYN		 PBM
Gabut et al.(2011)
pEX0123 		0.751 0.901
FOXP1
M00837_2.00 		Homo sapiens
DGTAAACAA
TTGTTTACH		 PBM
Gabut et al.(2011)
pEX0124 		0.751 0.901
FOXP1
M01976_2.00 		Homo sapiens
RTAAACAA
TTGTTTAY		 PBM
Weirauch et al.(2014)
pTH5656 		0.751 0.901
Foxp1
M00793_2.00 		Mus musculus
NRTMAAYAN
NTRTTKAYN		 PBM
Weirauch et al.(2013)
pTH3855 		0.751 0.901
FOXP1
M04811_2.00 		Homo sapiens
NTGTTTRYNRTNNNNNNBNAYRVWMAACAN
NTGTTKWBYRTNVNNNNNNAYNRYAAACAN		 SELEX
Yin et al.(2017)
FOXP1_eDBD_HT-SELEX 		0.751 0.901
FOXP1
M08115_2.00 		Homo sapiens
NDGTAAACAVNN
NNBTGTTTACHN		 ChIP-seq
Mathelier et al.(2014)
MA0481.2 		0.751 0.901
FOXP1
M09086_2.00 		Homo sapiens
RKAAACAVM
KBTGTTTMY		 Misc
Kulakovskiy et al.(2013)
FOXP1_HUMAN.H11MO.0.A 		0.751 0.901
FOXP1
M09541_2.00 		Homo sapiens
NDGTAAACAVNN
NNBTGTTTACHN		 Misc
Heinz et al.(2010)
H9-FOXP1_GSE31006 		0.751 0.901
FOXP1
M10536_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$FOXP1_01 		0.751 0.901
FOXP1
M04812_2.00 		Homo sapiens
NTGTTTRYBRTNNNNNNBNAYRVWMAACAH
DTGTTKWBYRTNVNNNNNNAYVRYAAACAN		 SELEX
Yin et al.(2017)
FOXP1_eDBD_Methyl-HT-SELEX 		0.751 0.901
FoxP
M03753_2.00 		Drosophila melanogaster
AAACAACAACAA
TTGTTGTTGTTT		 SELEX
Nitta et al.(2015)
CG16899_1 		0.725 0.728
FoxP
M06201_2.00 		Drosophila melanogaster
VRTAAACAA
TTGTTTAYB		 B1H
Zhu et al.(2011)
CG16899_SANGER_5_FBgn0037735 		0.725 0.728
FoxP
M06202_2.00 		Drosophila melanogaster
VNNVBBAAAAAAAD
HTTTTTTTVVBNNB		 B1H
Zhu et al.(2011)
CG2052_SANGER_2.5_FBgn0039905 		0.725 0.728
FoxP
M06203_2.00 		Drosophila melanogaster
NNNNNRAAAAAAWNN
NNWTTTTTTYNNNNN		 B1H
Zhu et al.(2011)
CG2052_SOLEXA_2.5_FBgn0039905 		0.725 0.728
SPU_025010
M01988_2.00 		Strongylocentrotus purpuratus
NNVNHHAYAN
NTRTDDNBNN		 PBM
Weirauch et al.(2014)
pTH6641 		0.667 0.457
For this family, TFs with SR scores > 0.664 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSRNOP00000069190 Forkhead 499 583

Links

Other Forkhead family TFs
Other Rattus norvegicus TFs

Invalid Input OrderBy

395 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action