let-381 (Caenorhabditis elegans)
Forkhead

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00250 (Forkhead) IPR001766 WBGene00002601 T188809_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
let-381
M00664_2.00
Caenorhabditis elegans
RTAAACAW

WTGTTTAY
PBM
Narasimhan et al.(2015)
pTH9057
(Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
foxe3
M01228_2.00
Xenopus tropicalis
WNNVHHMAYW

WRTKDDBNNW
PBM
Lambert et al.(2019)
pTH9824
0.745 0.523
FOXE1
M04845_2.00
Homo sapiens
BVYTAWRYAAACADN

NHTGTTTRYWTARBV
SELEX
Yin et al.(2017)
FOXE1_eDBD_HT-SELEX
0.727 0.512
FOXE1
M04846_2.00
Homo sapiens
BVYTAARYAAACAWH

DWTGTTTRYTTARBV
SELEX
Yin et al.(2017)
FOXE1_eDBD_Methyl-HT-SELEX
0.727 0.512
FOXD3
M03044_2.00
Homo sapiens
NRTMAAYRTTWDYN

NRHWAAYRTTKAYN
SELEX
Jolma et al.(2013)
FOXD3_1
0.726 0.500
FOXD3
M03045_2.00
Homo sapiens
RTAAAYA

TRTTTAY
SELEX
Jolma et al.(2013)
FOXD3_2
0.726 0.500
FOXD3
M04855_2.00
Homo sapiens
VHWRHRTAMACW

WGTKTAYDYWDB
SELEX
Yin et al.(2017)
FOXD3_eDBD_HT-SELEX
0.726 0.500
Foxd3
M09114_2.00
Mus musculus
DVNWRDRNAAACAVN

NBTGTTTNYHYWNBH
Misc
Kulakovskiy et al.(2013)
FOXD3_MOUSE.H11MO.0.C
0.726 0.500
FOXD3
M10565_2.00
Homo sapiens
RADHAAAYAWWH

DWWTRTTTDHTY
Transfac
Matys et al.(2006)
V$FOXD3_01
0.726 0.500
FOXD3
M10566_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$HFH2_Q5
0.726 0.500
FOXD3
M04856_2.00
Homo sapiens
VYWRHRTAAACW

WGTTTAYDYWRB
SELEX
Yin et al.(2017)
FOXD3_eDBD_Methyl-HT-SELEX
0.726 0.500
FOXC1
M00257_2.00
Homo sapiens
NNNVHHAAYA

TRTTDDBNNN
PBM
Barrera et al.(2016)
FOXC1_REF
0.722 0.558
Foxc1
M01982_2.00
Mus musculus
HNNRHMAAYA

TRTTKDYNND
PBM
Weirauch et al.(2014)
pTH2673
0.722 0.558
FOXC1
M03013_2.00
Homo sapiens
AWRTAAAYAAAYA

TRTTTRTTTAYWT
SELEX
Jolma et al.(2013)
FOXC1_1
0.722 0.558
FOXC1
M03014_2.00
Homo sapiens
NRWMAATATTKWYN

NRWMAATATTKWYN
SELEX
Jolma et al.(2013)
FOXC1_2
0.722 0.558
FOXC1
M03015_2.00
Homo sapiens
WRWRTMAAYAW

WTRTTKAYWYW
SELEX
Jolma et al.(2013)
FOXC1_3
0.722 0.558
Foxc1
M03059_2.00
Mus musculus
RTAAAYAAACA

TGTTTRTTTAY
SELEX
Jolma et al.(2013)
Foxc1_1
0.722 0.558
Foxc1
M03060_2.00
Mus musculus
RTAAACA

TGTTTAY
SELEX
Jolma et al.(2013)
Foxc1_2
0.722 0.558
FOXC1
M09083_2.00
Homo sapiens
SBWAWRTAAACADHN

NDHTGTTTAYWTWVS
Misc
Kulakovskiy et al.(2013)
FOXC1_HUMAN.H11MO.0.C
0.722 0.558
Foxc1
M09111_2.00
Mus musculus
SBWAWRTAAACADHN

NDHTGTTTAYWTWVS
Misc
Kulakovskiy et al.(2013)
FOXC1_MOUSE.H11MO.0.C
0.722 0.558
FOXC1
M10525_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$FOXC1_Q4
0.722 0.558
FOXC1
M10526_2.00
Homo sapiens
TSTTTATTTACDBNVN

NBNVHGTAAATAAASA
Transfac
Matys et al.(2006)
V$FREAC3_01
0.722 0.558
FOXC1
M00253_2.00
Homo sapiens
NNHATAAWHAN

NTDWTTATDNN
PBM
Barrera et al.(2016)
FOXC1_F112S
0.722 0.547
FOXC1
M00255_2.00
Homo sapiens
NRTATATWHNNN

NNNDWATATAYN
PBM
Barrera et al.(2016)
FOXC1_L130F
0.722 0.547
FOXC1
M00256_2.00
Homo sapiens
NNNNWWTYAMAWN

NWTKTRAWWNNNN
PBM
Barrera et al.(2016)
FOXC1_P79L
0.722 0.547
FOXC1
M00258_2.00
Homo sapiens
NNNAMAAYANN

NNTRTTKTNNN
PBM
Barrera et al.(2016)
FOXC1_S131L
0.722 0.547
FOXC1
M00259_2.00
Homo sapiens
RTAAACAW

WTGTTTAY
PBM
Barrera et al.(2016)
FOXC1_S82T
0.722 0.547
FOXF2
M02680_2.00
Homo sapiens
BNHNSRTAAACAHN

NDTGTTTAYSNDNV
SELEX
Mathelier et al.(2014)
MA0030.1
0.716 0.663
FOXF2
M10548_2.00
Homo sapiens
BNHNBRTAAACAHNVN

NBNDTGTTTAYVNDNV
Transfac
Matys et al.(2006)
V$FREAC2_01
0.716 0.663
FOXF1
M10529_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$FKHL5_Q3
0.711 0.663
FOXF1
M10530_2.00
Homo sapiens
YRHATAAACAHNB

VNDTGTTTATDYR
Transfac
Matys et al.(2006)
V$HFH8_01
0.711 0.663
fd59A
M03739_2.00
Drosophila melanogaster
HWAWRTAAACAWW

WWTGTTTAYWTWD
SELEX
Nitta et al.(2015)
fd59A_1
0.708 0.477
fd59A
M03740_2.00
Drosophila melanogaster
WWAVAATAACAHN

NDTGTTATTBTWW
SELEX
Nitta et al.(2015)
fd59A_2
0.708 0.477
fd59A
M03741_2.00
Drosophila melanogaster
YWRWRTAAAYAHH

DDTRTTTAYWYWR
SELEX
Nitta et al.(2015)
fd59A_3
0.708 0.477
fd59A
M03742_2.00
Drosophila melanogaster
MWACAAYAAYAHW

WDTRTTRTTGTWK
SELEX
Nitta et al.(2015)
fd59A_4
0.708 0.477
FOXL2
M04847_2.00
Homo sapiens
NVBGHMAACAH

DTGTTKDCVBN
SELEX
Yin et al.(2017)
FOXL2_FL_HT-SELEX
0.705 0.547
Foxl2
M09112_2.00
Mus musculus
DWDWRTAAACA

TGTTTAYWHWH
Misc
Kulakovskiy et al.(2013)
FOXL2_MOUSE.H11MO.0.C
0.705 0.547
FOXL2
M10560_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$FOXL2_Q2
0.705 0.547
FOXL2
M10561_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$FOXL2_Q5
0.705 0.547
FOXL2
M04848_2.00
Homo sapiens
HVCGWMAACAH

DTGTTKWCGBD
SELEX
Yin et al.(2017)
FOXL2_FL_Methyl-HT-SELEX
0.705 0.547
Foxl1
M00164_2.00
Mus musculus
NNNRTMAAYA

TRTTKAYNNN
PBM
Badis et al.(2009)
Foxl1_2809
0.703 0.547
FOXL1
M03034_2.00
Homo sapiens
RTAAACA

TGTTTAY
SELEX
Jolma et al.(2013)
FOXL1_1
0.703 0.535
FOXL1
M03035_2.00
Homo sapiens
NRTAAAYAAAYAN

NTRTTTRTTTAYN
SELEX
Jolma et al.(2013)
FOXL1_2
0.703 0.535
FOXL1
M10558_2.00
Homo sapiens
DHNVHATAAAYAHNNN

NNNDTRTTTATDBNDH
Transfac
Matys et al.(2006)
V$FREAC7_01
0.703 0.535
FOXD4L4
M10564_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$FOXD4L4_01
0.698 0.465
FOXC1
M00254_2.00
Homo sapiens
RRTAAACANN

NNTGTTTAYY
PBM
Barrera et al.(2016)
FOXC1_I126M
0.697 0.547
Gm5294
M01984_2.00
Mus musculus
NNKRTAAACANN

NNTGTTTAYMNN
PBM
Weirauch et al.(2014)
pTH3802
0.695 0.488
FOXD2
M03042_2.00
Homo sapiens
NRTMAAYRTTWDYN

NRHWAAYRTTKAYN
SELEX
Jolma et al.(2013)
FOXD2_1
0.694 0.488
FOXD2
M03043_2.00
Homo sapiens
RTAAAYA

TRTTTAY
SELEX
Jolma et al.(2013)
FOXD2_2
0.694 0.488
FOXD2
M04851_2.00
Homo sapiens
HWASAATAAYAWWN

NWWTRTTATTSTWD
SELEX
Yin et al.(2017)
FOXD2_eDBD_HT-SELEX_1
0.694 0.488
FOXD2
M04852_2.00
Homo sapiens
VYWANRTAAAYAH

DTRTTTAYNTWRB
SELEX
Yin et al.(2017)
FOXD2_eDBD_HT-SELEX_2
0.694 0.488
FOXD1
M02681_2.00
Homo sapiens
GTAAACAD

HTGTTTAC
SELEX
Mathelier et al.(2014)
MA0031.1
0.694 0.488
Foxd1
M10570_2.00
Mus musculus
SYWAWGTAAACADHVN

NBDHTGTTTACWTWRS
Transfac
Matys et al.(2006)
V$FREAC4_01
0.694 0.488
FOXD1
M10567_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$FREAC4_02
0.694 0.488
FOXD2
M04853_2.00
Homo sapiens
HWACAATAACRWWN

NWWYGTTATTGTWD
SELEX
Yin et al.(2017)
FOXD2_eDBD_Methyl-HT-SELEX_1
0.694 0.488
FOXD2
M04854_2.00
Homo sapiens
RYTRNGTMAACRD

HYGTTKACNYARY
SELEX
Yin et al.(2017)
FOXD2_eDBD_Methyl-HT-SELEX_2
0.694 0.488
bin
M03752_2.00
Drosophila melanogaster
HTAATGTAAACAAW

WTTGTTTACATTAD
SELEX
Nitta et al.(2015)
bin_1
0.690 0.570
bin
M06199_2.00
Drosophila melanogaster
TAAACARVGA

TCBYTGTTTA
B1H
Zhu et al.(2011)
bin_FlyReg_FBgn0045759
0.690 0.570
bin
M06200_2.00
Drosophila melanogaster
RTAAACA

TGTTTAY
B1H
Zhu et al.(2011)
bin_SANGER_5_FBgn0045759
0.690 0.570
Foxc2
M00796_2.00
Mus musculus
HNNRHMAAYA

TRTTKDYNND
PBM
Weirauch et al.(2013)
pTH3796
0.689 0.547
FOXC2
M03036_2.00
Homo sapiens
NRTMAATATTDWYN

NRWHAATATTKAYN
SELEX
Jolma et al.(2013)
FOXC2_1
0.689 0.547
FOXC2
M03037_2.00
Homo sapiens
RTAAAYAAACA

TGTTTRTTTAY
SELEX
Jolma et al.(2013)
FOXC2_2
0.689 0.547
FOXC2
M03038_2.00
Homo sapiens
WAHRTMAAYAWW

WWTRTTKAYDTW
SELEX
Jolma et al.(2013)
FOXC2_3
0.689 0.547
FOXC2
M04841_2.00
Homo sapiens
NHVNRYMAACAH

DTGTTKRYNBDN
SELEX
Yin et al.(2017)
FOXC2_eDBD_HT-SELEX_1
0.689 0.547
FOXC2
M04842_2.00
Homo sapiens
RHAMAYAAACAH

DTGTTTRTKTDY
SELEX
Yin et al.(2017)
FOXC2_eDBD_HT-SELEX_2
0.689 0.547
FOXC2
M10559_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$FKHL14_Q2
0.689 0.547
FOXC2
M04843_2.00
Homo sapiens
NHNNRYMAACAN

NTGTTKRYNNDN
SELEX
Yin et al.(2017)
FOXC2_eDBD_Methyl-HT-SELEX_1
0.689 0.547
FOXC2
M04844_2.00
Homo sapiens
VHMMAYAAACAN

NTGTTTRTKKDB
SELEX
Yin et al.(2017)
FOXC2_eDBD_Methyl-HT-SELEX_2
0.689 0.547
fd64A
M06197_2.00
Drosophila melanogaster
KVWAAACA

TGTTTWBM
B1H
Zhu et al.(2011)
fd64A_SANGER_5_FBgn0004895
0.689 0.535
croc
M03744_2.00
Drosophila melanogaster
WRYGTMAACAH

DTGTTKACRYW
SELEX
Nitta et al.(2015)
croc_1
0.676 0.547
croc
M10571_2.00
Drosophila melanogaster
HWNARTAAATAKNNNV

BNNNMTATTTAYYNWD
Transfac
Matys et al.(2006)
I$CROC_01
0.676 0.547
FOXI1
M03026_2.00
Homo sapiens
GTAAACA

TGTTTAC
SELEX
Jolma et al.(2013)
FOXI1_1
0.671 0.547
FOXI1
M03027_2.00
Homo sapiens
RTGTKTACGGTAAACAA

TTGTTTACCGTAMACAY
SELEX
Jolma et al.(2013)
FOXI1_2
0.671 0.547
FOXI1
M04827_2.00
Homo sapiens
NNNNNRTMAACAN

NTGTTKAYNNNNN
SELEX
Yin et al.(2017)
FOXI1_eDBD_HT-SELEX
0.671 0.547
FOXI1
M04829_2.00
Homo sapiens
AAYGTAAACAMW

WKTGTTTACRTT
SELEX
Yin et al.(2017)
FOXI1_FL_HT-SELEX
0.671 0.547
FOXI1
M09095_2.00
Homo sapiens
RRCCAATCAVAD

HTBTGATTGGYY
Misc
Kulakovskiy et al.(2013)
FOXI1_HUMAN.H11MO.0.B
0.671 0.547
FOXI1
M10556_2.00
Homo sapiens
HAWAYAAAYAHVH

DBDTRTTTRTWTD
Transfac
Matys et al.(2006)
V$HFH3_01
0.671 0.547
FOXI1
M04828_2.00
Homo sapiens
NWWVHRTAAACAH

DTGTTTAYDBWWN
SELEX
Yin et al.(2017)
FOXI1_eDBD_Methyl-HT-SELEX
0.671 0.547
FOXI1
M04830_2.00
Homo sapiens
AAYRTAAACAAW

WTTGTTTAYRTT
SELEX
Yin et al.(2017)
FOXI1_FL_Methyl-HT-SELEX
0.671 0.547
Foxi1
M09109_2.00
Mus musculus
RRCCAATCAVAD

HTBTGATTGGYY
Misc
Kulakovskiy et al.(2013)
FOXI1_MOUSE.H11MO.0.B
0.671 0.535
For this family, TFs with SR scores > 0.664 will likely have a similar motif

Experimental Constructs

Motif ID Domain From To Sequence
M00664_2.00 Forkhead 51 143

DNA Binding Domains

Protein ID Domain From To Sequence
F26B1.7 Forkhead 72 164

Links

Other Forkhead family TFs
Other Caenorhabditis elegans TFs

1097 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action
29938.m000611 Ricinus communis 29938.m000611 I 0.000
cassava8476.m1 Manihot esculenta cassava8476.m1 I 0.000
Ca_15055 Cicer arietinum Ca_15055 I 0.000
chr2.CM0018.340.nd Lotus japonicus chr2.CM0018.340.nd I 0.000
Ciclev10023345m.g Citrus clementina Ciclev10023345m.g I 0.000
Cla012182 Citrullus lanatus Cla012182 I 0.000
Cucsa.088640 Cucumis sativus Cucsa.088640 N 0.000
Eucgr.F02967 Eucalyptus grandis Eucgr.F02967 I 0.000
evm.TU.supercontig_21.63 Carica papaya evm.TU.supercontig_21.63 I 0.000
GLYMA01G44230 Glycine max GLYMA01G44230 N 0.000
GLYMA11G01700 Glycine max GLYMA11G01700 I 0.000
Lus10006179.g Linum usitatissimum Lus10006179.g I 0.000
Lus10009468.g Linum usitatissimum Lus10009468.g I 0.000
Lus10041044.g Linum usitatissimum Lus10041044.g I 0.000
mgf010891m Mimulus guttatus mgf010891m I 0.000
MTR_5g008790 Medicago truncatula MTR_5g008790 I 0.000
orange1.1g045327m.g Citrus sinensis orange1.1g045327m.g I 0.000
POPTR_0013s10420 Populus trichocarpa POPTR_0013s10420 I 0.000
POPTR_0019s10220 Populus trichocarpa POPTR_0019s10220 I 0.000
SapurV1A.2173s0020 Salix purpurea SapurV1A.2173s0020 I 0.000
SapurV1A.3847s0010 Salix purpurea SapurV1A.3847s0010 I 0.000
SapurV1A.4200s0010 Salix purpurea SapurV1A.4200s0010 I 0.000
Solyc01g057080.1 Solanum lycopersicum Solyc01g057080.1 N 0.000