|
|
HHAL010341-PA
(Halyomorpha halys)
Forkhead
|
TF Information |
|---|
| Pfam ID |
Interpro ID |
Gene ID |
CIS-BP ID |
Sequence source |
| PF00250 (Forkhead) |
IPR001766 |
HHAL010341-PA |
T189533_2.00 |
Misc (2018-Jan-19) |
| NCBI Gene Info:This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277). [provided by RefSeq, Dec 2016] |
Directly determined binding motifs |
|---|
| Name/Motif ID |
Species |
Forward |
Reverse |
Type/Study/Study ID |
SR
Score |
DBD
Identity |
| No direct experiments |
|
|
|
|
|
Motifs from related TFs |
|---|
| Name/Motif ID |
Species |
Forward |
Reverse |
Type/Study/Study ID |
SR
Score |
DBD
Identity |
fd96Ca
M03743_2.00 |
Drosophila melanogaster |
WRWGYMAATATTKRCWYW |
WRWGYMAATATTKRCWYW |
SELEX
Nitta et al.(2015)
fd96Ca_1
|
0.760
|
0.867
|
Foxb1
M01983_2.00 |
Mus musculus |
TRTTKAYWYW |
WRWRTMAAYA |
PBM
Weirauch et al.(2014)
pTH2808
|
0.759
|
0.800
|
FOXB1
M03028_2.00 |
Homo sapiens |
GAATGACACRGCKV |
BMGCYGTGTCATTC |
SELEX
Jolma et al.(2013)
FOXB1_1
|
0.759
|
0.800
|
FOXB1
M03029_2.00 |
Homo sapiens |
WRWGTMAATATTKACWYW |
WRWGTMAATATTKACWYW |
SELEX
Jolma et al.(2013)
FOXB1_2
|
0.759
|
0.800
|
FOXB1
M03030_2.00 |
Homo sapiens |
WTRTTKACWTW |
WAWGTMAAYAW |
SELEX
Jolma et al.(2013)
FOXB1_3
|
0.759
|
0.800
|
FOXB1
M03031_2.00 |
Homo sapiens |
NTRTTTACW |
WGTAAAYAN |
SELEX
Jolma et al.(2013)
FOXB1_4
|
0.759
|
0.800
|
FOXB1
M04837_2.00 |
Homo sapiens |
NWRDGYMAATATTKRCWYWD |
HWRWGYMAATATTKRCHYWN |
SELEX
Yin et al.(2017)
FOXB1_eDBD_HT-SELEX
|
0.759
|
0.800
|
FOXB1
M04838_2.00 |
Homo sapiens |
NWRNGYMAATATTKRCDYWD |
HWRHGYMAATATTKRCNYWN |
SELEX
Yin et al.(2017)
FOXB1_eDBD_Methyl-HT-SELEX
|
0.759
|
0.800
|
lin-31
M00665_2.00 |
Caenorhabditis elegans |
NWRTAAAYANN |
NNTRTTTAYWN |
PBM
Narasimhan et al.(2015)
pTH9116
|
0.751
|
0.760
|
| For this family, TFs with SR scores > 0.664 will likely have a similar motif |