TRPS1 (Homo sapiens)
GATA

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00320 (GATA) IPR000679 ENSG00000104447 T192723_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
This gene encodes a transcription factor that represses GATA-regulated genes and binds to a dynein light chain protein. Binding of the encoded protein to the dynein light chain protein affects binding to GATA consensus sequences and suppresses its transcriptional activity. Defects in this gene are a cause of tricho-rhino-phalangeal syndrome (TRPS) types I-III. [provided by RefSeq, Jul 2008]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
TRPS1
M10585_2.00		 Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$TRPS1_Q3		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
GATAe
M03761_2.00 		Drosophila melanogaster
VHGATAAS
STTATCDB		 SELEX
Nitta et al.(2015)
GATAe_1 		0.822 0.629
GATAe
M03762_2.00 		Drosophila melanogaster
HGATAACNNNGTTATCD
HGATAACNNNGTTATCD		 SELEX
Nitta et al.(2015)
GATAe_2 		0.822 0.629
GATAe
M03763_2.00 		Drosophila melanogaster
HGATAAGNNNCTTATCD
HGATAAGNNNCTTATCD		 SELEX
Nitta et al.(2015)
GATAe_3 		0.822 0.629
GATAe
M06208_2.00 		Drosophila melanogaster
WGATAAG
CTTATCW		 B1H
Zhu et al.(2011)
GATAe_SANGER_5_FBgn0038391 		0.822 0.629
nit-2
M02017_2.00 		Neurospora crassa
NNGATHNN
NNDATCNN		 PBM
Weirauch et al.(2014)
pTH8624 		0.808 0.543
nit-2
M10601_2.00 		Neurospora crassa
DHGATA
TATCDH		 Transfac
Matys et al.(2006)
F$NIT2_01 		0.808 0.543
For this family, TFs with SR scores > 0.802 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000220888 GATA 896 930
ENSP00000379065 GATA 909 943
ENSP00000428121 GATA 21 55
ENSP00000428680 GATA 900 934
ENSP00000428910 GATA 650 684
ENSP00000430803 BED ZF 218 252
ENSP00000430803 BED ZF 328 363

Links

Other GATA family TFs
Other Homo sapiens TFs

Invalid Input OrderBy

438 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action