GATAe (Drosophila melanogaster)
GATA

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00320 (GATA) IPR000679 FBgn0038391 T193204_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including columnar/cuboidal epithelial cell differentiation; intestinal stem cell homeostasis; and regulation of gene expression. Located in nucleus. Is expressed in several structures, including anterior endoderm anlage; gastrula embryo; germ layer derivative; gut; and proventriculus primordium. Human ortholog(s) of this gene implicated in congenital heart disease (multiple). Orthologous to human GATA4 (GATA binding protein 4) and GATA5 (GATA binding protein 5). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
GATAe
M03761_2.00		 Drosophila melanogaster
VHGATAAS
STTATCDB		 SELEX
Nitta et al.(2015)
GATAe_1		 (Direct) (Direct)
GATAe
M03762_2.00		 Drosophila melanogaster
HGATAACNNNGTTATCD
HGATAACNNNGTTATCD		 SELEX
Nitta et al.(2015)
GATAe_2		 (Direct) (Direct)
GATAe
M03763_2.00		 Drosophila melanogaster
HGATAAGNNNCTTATCD
HGATAAGNNNCTTATCD		 SELEX
Nitta et al.(2015)
GATAe_3		 (Direct) (Direct)
GATAe
M06208_2.00		 Drosophila melanogaster
WGATAAG
CTTATCW		 B1H
Zhu et al.(2011)
GATAe_SANGER_5_FBgn0038391		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
nit-2
M02017_2.00 		Neurospora crassa
NNGATHNN
NNDATCNN		 PBM
Weirauch et al.(2014)
pTH8624 		0.822 0.600
nit-2
M10601_2.00 		Neurospora crassa
DHGATA
TATCDH		 Transfac
Matys et al.(2006)
F$NIT2_01 		0.822 0.600
For this family, TFs with SR scores > 0.802 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
FBpp0082672 GATA 539 573
FBpp0292352 GATA 524 558
FBpp0292353 GATA 524 558

Links

Other GATA family TFs
Other Drosophila melanogaster TFs

Invalid Input OrderBy

439 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action