TF Information

elt-2 *(Caenorhabditis elegans)* GATA
Pfam ID	Interpro ID	Gene ID	CIS-BP ID	Sequence source	Animal TF db
PF00320 (GATA)	IPR000679	WBGene00001250	T195702_2.00	Ensembl (2018-Dec-8)	Link out
NCBI Gene Info: Enables DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II transcription regulatory region sequence-specific DNA binding activity; and enzyme inhibitor activity. Involved in several processes, including defense response to other organism; endoderm development; and nematode larval development. Located in nucleus. Is expressed in several structures, including Ea; Eal; anal region; head neurons; and intestine. Human ortholog(s) of this gene implicated in adenocarcinoma (multiple); congenital heart disease (multiple); and pancreatic hypoplasia-diabetes-congenital heart disease syndrome. Orthologous to human GATA4 (GATA binding protein 4); GATA5 (GATA binding protein 5); and GATA6 (GATA binding protein 6). [provided by Alliance of Genome Resources, Apr 2022]
Directly determined binding motifs
Name/Motif ID	Species	Forward	Reverse	Type/Study/Study ID	SR Score	DBD Identity
No direct experiments
Motifs from related TFs
Name/Motif ID	Species	Forward	Reverse	Type/Study/Study ID	SR Score	DBD Identity
GATAe M03761_2.00	Drosophila melanogaster	VHGATAAS	STTATCDB	SELEX Nitta et al.(2015) GATAe_1	0.842	0.686
GATAe M03762_2.00	Drosophila melanogaster	HGATAACNNNGTTATCD	HGATAACNNNGTTATCD	SELEX Nitta et al.(2015) GATAe_2	0.842	0.686
GATAe M03763_2.00	Drosophila melanogaster	HGATAAGNNNCTTATCD	HGATAAGNNNCTTATCD	SELEX Nitta et al.(2015) GATAe_3	0.842	0.686
GATAe M06208_2.00	Drosophila melanogaster	WGATAAG	CTTATCW	B1H Zhu et al.(2011) GATAe_SANGER_5_FBgn0038391	0.842	0.686
nit-2 M02017_2.00	Neurospora crassa	NNGATHNN	NNDATCNN	PBM Weirauch et al.(2014) pTH8624	0.817	0.571
nit-2 M10601_2.00	Neurospora crassa	DHGATA	TATCDH	Transfac Matys et al.(2006) F$NIT2_01	0.817	0.571
For this family, TFs with SR scores > 0.802* will likely have a similar motif*