ENSBTAP00000011018-D1 (Bos grunniens)
Grainyhead

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source
PF04516 (CP2) IPR007604 ENSBTAP00000011018-D1 T199519_2.00 GigaDB (2015-Oct-22)
NCBI Gene Info:
This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277). [provided by RefSeq, Dec 2016]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
No TFs with similar DNA binding domains

DNA Binding Domains

Protein ID Domain From To Sequence
ENSBTAP00000011018-D1 Grainyhead 8 188

Links

Other Grainyhead family TFs
Other Bos grunniens TFs

11 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action
ENSBTAG00000008368 Bos taurus ENSBTAG00000008368 N 0.874
ENSFCAG00000023653 Felis catus ENSFCAG00000023653 N 0.806
ENSMLUG00000030674 Myotis lucifugus ENSMLUG00000030674 N 0.783
Myotis_brandtii_TFCP2L1_10030397 Myotis brandtii Myotis_brandtii_TFCP2L1_10030397 N 0.783
ENSLAFG00000031473 Loxodonta africana ENSLAFG00000031473 N 0.777
ENSAMEG00000004034 Ailuropoda melanoleuca ENSAMEG00000004034 N 0.771
ENSECAG00000023454 Equus caballus ENSECAG00000023454 I 0.771
ENSOARG00000010734 Ovis aries ENSOARG00000010734 N 0.766
ENSCAFG00000016470 Canis familiaris ENSCAFG00000016470 N 0.766
ENSMODG00000012723 Monodelphis domestica ENSMODG00000012723 N 0.726
ENSSHAG00000016282 Sarcophilus harrisii ENSSHAG00000016282 N 0.714