CIS-BP Database: Catalog of Inferred Sequence Binding Preferences
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ENSP00000257915
(
Macaca fascicularis
)
Grainyhead
TF Information
Pfam ID
Interpro ID
Gene ID
CIS-BP ID
Sequence source
PF04516 (CP2)
IPR007604
ENSP00000257915
T199524_2.00
GigaDB (2015-Oct-22)
NCBI Gene Info:
This gene encodes a transcription factor that binds the alpha-globin promoter and activates transcription of the alpha-globin gene. The encoded protein regulates erythroid gene expression, plays a role in the transcriptional switch of globin gene promoters, and it activates many other cellular and viral gene promoters. The gene product interacts with certain inflammatory response factors, and polymorphisms of this gene may be involved in the pathogenesis of Alzheimer's disease. [provided by RefSeq, Mar 2010]
Directly determined binding motifs
Name/Motif ID
Species
Forward
Reverse
Type/Study/Study ID
SR
Score
DBD
Identity
No direct experiments
Motifs from related TFs
Name/Motif ID
Species
Forward
Reverse
Type/Study/Study ID
SR
Score
DBD
Identity
ENSGALG00000002235
M02030_2.00
Gallus gallus
AACCGGTTA
TAACCGGTT
PBM
Weirauch et al.(2014)
pTH8565
0.913
0.913
UBP1
M04893_2.00
Homo sapiens
NDCYRGHNNNNDCYRGHN
NDCYRGHNNNNDCYRGHN
SELEX
Yin et al.(2017)
UBP1_eDBD_HT-SELEX
0.879
0.879
UBP1
M10614_2.00
Homo sapiens
Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$LBP1_Q6_01
0.879
0.879
UBP1
M10615_2.00
Homo sapiens
Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$LBP1_Q6
0.879
0.879
UBP1
M04894_2.00
Homo sapiens
DWCYRGHHNNDDCYRGWH
DWCYRGHHNNDDCYRGWH
SELEX
Yin et al.(2017)
UBP1_eDBD_Methyl-HT-SELEX
0.879
0.879
TFCP2
M03074_2.00
Homo sapiens
DAWCCGGTTY
RAACCGGWTH
SELEX
Jolma et al.(2013)
TFCP2_1
0.840
0.840
TFCP2
M03075_2.00
Homo sapiens
WCCGGWWHDAWCYGGW
WCCRGWTHDWWCCGGW
SELEX
Jolma et al.(2013)
TFCP2_2
0.840
0.840
TFCP2
M04889_2.00
Homo sapiens
DWCYRGWHNNDWCYRGWH
DWCYRGWHNNDWCYRGWH
SELEX
Yin et al.(2017)
TFCP2_eDBD_HT-SELEX
0.840
0.840
TFCP2
M04891_2.00
Homo sapiens
AWCYGGTTHNDACCGGTW
WACCGGTHNDAACCRGWT
SELEX
Yin et al.(2017)
TFCP2_FL_HT-SELEX
0.840
0.840
TFCP2
M10610_2.00
Homo sapiens
CTKGKTHKDGC
GCHMDAMCMAG
Transfac
Matys et al.(2006)
V$CP2_01
0.840
0.840
TFCP2
M10611_2.00
Homo sapiens
Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$CP2_02
0.840
0.840
TFCP2
M10612_2.00
Homo sapiens
Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$CP2_Q4
0.840
0.840
TFCP2
M10613_2.00
Homo sapiens
Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$CP2_Q6
0.840
0.840
TFCP2
M04890_2.00
Homo sapiens
DWCYRGWHNNDWCYRGWH
DWCYRGWHNNDWCYRGWH
SELEX
Yin et al.(2017)
TFCP2_eDBD_Methyl-HT-SELEX
0.840
0.840
TFCP2
M04892_2.00
Homo sapiens
AWCCGGWTNDAWCCGGTT
AACCGGWTHNAACCGGWT
SELEX
Yin et al.(2017)
TFCP2_FL_Methyl-HT-SELEX
0.840
0.840
TFCP2L1
M04885_2.00
Homo sapiens
DCYRGHHNNNDCYRGH
DCYRGHNNNDDCYRGH
SELEX
Yin et al.(2017)
TFCP2L1_eDBD_HT-SELEX
0.806
0.806
TFCP2L1
M10609_2.00
Homo sapiens
Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$LBP9_01
0.806
0.806
TFCP2L1
M04886_2.00
Homo sapiens
DCYRGHHNNDDCYRGH
DCYRGHHNNDDCYRGH
SELEX
Yin et al.(2017)
TFCP2L1_eDBD_Methyl-HT-SELEX
0.806
0.806
Tcfcp2l1
M08029_2.00
Mus musculus
CYRGYYYHDDCYRGHYYNNNN
NNNNRRDCYRGHHDRRRCYRG
ChIP-seq
Chen et al.(2011)
SRP000217_Tcfc2pI1
0.782
0.782
Tcfcp2l1
M08030_2.00
Mus musculus
CYRGYYYHDDCYRGHYYNNNN
NNNNRRDCYRGHHDRRRCYRG
ChIP-seq
Chen et al.(2011)
SRP000217_Tcfcp2I1
0.782
0.782
Tcfcp2l1
M09127_2.00
Mus musculus
DDCYRGYTYHNDCYRGHYB
VRDCYRGHNDRARCYRGHH
Misc
Kulakovskiy et al.(2013)
TF2L1_MOUSE.H11MO.0.C
0.782
0.782
For this family, TFs with SR scores >
0.700
will likely have a similar motif
DNA Binding Domains
Protein ID
Domain
From
To
Sequence
ENSP00000257915
Grainyhead
9
223
LPIFKQEESSLPPDNENKILPFQYVLCAATSPAVKLHDETLTYLNQGQSYEIRMLDNRKLGELPEINGKLVKSIFRVVFHDRRLQYTEHQQLEGWRWNRPGDRILDIDIPMSVGIIDPRANPTQLNTVEFLWDPAKRTSVFIQVHCISTEFTMRKHGGEKGVPFRVQIDTFKENENGEYTEHLHSASCQIKVFKPKGADRKQKTDREKMEKRTPH
Links
Other
Grainyhead
family TFs
Other
Macaca fascicularis
TFs
194 Related TFs
Name
Species
Gene ID
Motif Evidence
SR
Score
Action
Invalid Input OrderBy