GTF2I (Homo sapiens)
GTF2I-like

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF02946 (GTF2I) IPR004212 ENSG00000263001 T203418_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
This gene encodes a phosphoprotein containing six characteristic repeat motifs. The encoded protein binds to the initiator element (Inr) and E-box element in promoters and functions as a regulator of transcription. This locus, along with several other neighboring genes, is deleted in Williams-Beuren syndrome. There are many closely related genes and pseudogenes for this gene on chromosome 7. This gene also has pseudogenes on chromosomes 9, 13, and 21. Alternatively spliced transcript variants encoding multiple isoforms have been observed. [provided by RefSeq, Jul 2013]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
GTF2I
M10621_2.00		 Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$TFIII_Q6_01		 (Direct) (Direct)
GTF2I
M10622_2.00		 Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$TFIII_Q6		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
For this family, TFs with SR scores > 0.700 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000404240 GTF2I-like 112 186
ENSP00000460070 GTF2I-like 112 186
ENSP00000460070 GTF2I-like 361 435
ENSP00000460070 GTF2I-like 466 540
ENSP00000460070 GTF2I-like 571 645
ENSP00000460070 GTF2I-like 733 807
ENSP00000460070 GTF2I-like 868 942
ENSP00000477837 GTF2I-like 112 186
ENSP00000477837 GTF2I-like 320 394
ENSP00000477837 GTF2I-like 425 499
ENSP00000477837 GTF2I-like 530 604
ENSP00000477837 GTF2I-like 692 766
ENSP00000477837 GTF2I-like 827 901
ENSP00000482476 GTF2I-like 112 186
ENSP00000482476 GTF2I-like 340 414
ENSP00000482476 GTF2I-like 445 519
ENSP00000482476 GTF2I-like 550 624
ENSP00000482476 GTF2I-like 712 786
ENSP00000482476 GTF2I-like 847 921
ENSP00000484526 GTF2I-like 112 186
ENSP00000484526 GTF2I-like 341 415
ENSP00000484526 GTF2I-like 446 520
ENSP00000484526 GTF2I-like 551 625
ENSP00000484526 GTF2I-like 713 787
ENSP00000484526 GTF2I-like 848 922

Links

Other GTF2I-like family TFs
Other Homo sapiens TFs

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57 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action