ENSP00000397566 (Macaca fascicularis)
GTF2I-like

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source
PF02946 (GTF2I) IPR004212 ENSP00000397566 T203567_2.00 GigaDB (2015-Oct-22)
NCBI Gene Info:
The protein encoded by this gene contains five GTF2I-like repeats and each repeat possesses a potential helix-loop-helix (HLH) motif. It may have the ability to interact with other HLH-proteins and function as a transcription factor or as a positive transcriptional regulator under the control of Retinoblastoma protein. This gene plays a role in craniofacial and cognitive development and mutations have been associated with Williams-Beuren syndrome, a multisystem developmental disorder caused by deletion of multiple genes at 7q11.23. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2010]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
GTF2IRD1
M10618_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$BEN_01 		0.779 0.779
GTF2IRD1
M10619_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$BEN_02 		0.779 0.779
GTF2IRD1
M10620_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$GTF2IRD1_01 		0.779 0.779
For this family, TFs with SR scores > 0.700 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000397566 GTF2I-like 160 234
ENSP00000397566 GTF2I-like 383 457
ENSP00000397566 GTF2I-like 597 671
ENSP00000397566 GTF2I-like 722 795

Links

Other GTF2I-like family TFs
Other Macaca fascicularis TFs

35 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
ENSMPUG00000016153 Mustela putorius furo ENSMPUG00000016153 I 0.900
GTF2IRD1 Meleagris gallopavo ENSMGAG00000016801 I 0.893
Tal_R007678 Tyto alba Tal_R007678 I 0.839
GTF2IRD1 Macaca mulatta ENSMMUG00000018842 I 0.779
ENSPPYG00000017485 Pongo abelii ENSPPYG00000017485 I 0.779
GTF2IRD1 Homo sapiens ENSG00000006704 D 0.779
GTF2IRD1 Pan troglodytes ENSPTRG00000019292 I 0.779
GTF2IRD1 Myotis lucifugus ENSMLUG00000001668 I 0.776
Myotis_brandtii_GTF2IRD1_10014286 Myotis brandtii Myotis_brandtii_GTF2IRD1_10014286 I 0.776
ENSSTOG00000014343 Ictidomys tridecemlineatus ENSSTOG00000014343 I 0.773
GTF2IRD1 Sus scrofa ENSSSCG00000007720 I 0.773
ENSAMEG00000015311 Ailuropoda melanoleuca ENSAMEG00000015311 I 0.773
ENSOARG00000011517 Ovis aries ENSOARG00000011517 I 0.773
GTF2IRD1 Equus caballus ENSECAG00000019745 I 0.773
GTF2IRD1 Felis catus ENSFCAG00000006551 I 0.773
GTF2IRD1 Canis familiaris ENSCAFG00000011763 I 0.773
GTF2IRD1 Bos taurus ENSBTAG00000006212 I 0.773
GTF2IRD1 Dasypus novemcinctus ENSDNOG00000024296 I 0.768
GTF2IRD1 Oryctolagus cuniculus ENSOCUG00000026916 I 0.768
GTF2IRD1 Cavia porcellus ENSCPOG00000004421 I 0.763
Gtf2ird1 Rattus norvegicus ENSRNOG00000001478 I 0.755
LOC100912262 Rattus norvegicus ENSRNOG00000050193 I 0.755
Gtf2ird1 Mus musculus ENSMUSG00000023079 I 0.755
ENSCSAG00000018202 Chlorocebus sabaeus ENSCSAG00000018202 N 0.749
gtf2ird1 Xenopus tropicalis XB-GENE-5857402 I 0.747
ENSMEUG00000012139 Macropus eugenii ENSMEUG00000012139 I 0.733
ENSAPLG00000006811 Anas platyrhynchos ENSAPLG00000006811 I 0.709
GTF2IRD1 Taeniopygia guttata ENSTGUG00000003638 I 0.709
Aan_R007261 Calypte anna Aan_R007261 I 0.709
ENSPSIG00000012562 Pelodiscus sinensis ENSPSIG00000012562 I 0.709
Gfo_R013537 Geospiza fortis Gfo_R013537 I 0.707
Afo_R005311 Aptenodytes forsteri Afo_R005311 I 0.707
Alligator_sinensis_CCG003099.1 Alligator sinensis Alligator_sinensis_CCG003099.1 I 0.707
Brh_R010572 Buceros rhinoceros Brh_R010572 I 0.707
GTF2IRD1 Loxodonta africana ENSLAFG00000006505 N 0.703