ENSP00000397566 (Macaca fascicularis)
GTF2I-like

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source
PF02946 (GTF2I) IPR004212 ENSP00000397566 T203567_2.00 GigaDB (2015-Oct-22)
NCBI Gene Info:
The protein encoded by this gene contains five GTF2I-like repeats and each repeat possesses a potential helix-loop-helix (HLH) motif. It may have the ability to interact with other HLH-proteins and function as a transcription factor or as a positive transcriptional regulator under the control of Retinoblastoma protein. This gene plays a role in craniofacial and cognitive development and mutations have been associated with Williams-Beuren syndrome, a multisystem developmental disorder caused by deletion of multiple genes at 7q11.23. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2010]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
GTF2IRD1
M10618_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$BEN_01 		0.779 0.779
GTF2IRD1
M10619_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$BEN_02 		0.779 0.779
GTF2IRD1
M10620_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$GTF2IRD1_01 		0.779 0.779
For this family, TFs with SR scores > 0.700 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000397566 GTF2I-like 160 234
ENSP00000397566 GTF2I-like 383 457
ENSP00000397566 GTF2I-like 597 671
ENSP00000397566 GTF2I-like 722 795

Links

Other GTF2I-like family TFs
Other Macaca fascicularis TFs

Invalid Input OrderBy

35 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action