CIS-BP Database: Catalog of Inferred Sequence Binding Preferences
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WOX1
(
Arabidopsis thaliana
)
Homeodomain
TF Information
Pfam ID
Interpro ID
Gene ID
CIS-BP ID
Sequence source
Animal TF db
PF00046 (Homeobox)
IPR001356
AT3G18010
T204492_2.00
Ensembl (2018-Dec-8)
Link out
NCBI Gene Info:
Homeobox gene controlling the stem cell pool. Expressed in the stem cell organizing center of meristems. Required to keep the stem cells in an undifferentiated state. Regulation of WUS transcription is a central checkpoint in stem cell control. The size of the WUS expression domain controls the size of the stem cell population through WUS indirectly activating the expression of CLAVATA3 (CLV3) in the stem cells and CLV3 repressing WUS transcription through the CLV1 receptor kinase signaling pathway. Repression of WUS transcription through AGAMOUS (AG) activity controls stem cell activity in the determinate floral meristem. Binds to TAAT element core motif. WUS is also involved in cell differentiation during anther development.
Directly determined binding motifs
Name/Motif ID
Species
Forward
Reverse
Type/Study/Study ID
SR
Score
DBD
Identity
No direct experiments
Motifs from related TFs
Name/Motif ID
Species
Forward
Reverse
Type/Study/Study ID
SR
Score
DBD
Identity
WUS
M06905_2.00
Arabidopsis thaliana
TRAWTGAWTGA
TCAWTCAWTYA
Dap-seq
OMalley et al.(2016)
WUS1_col_a
0.740
0.702
WUS
M06906_2.00
Arabidopsis thaliana
TGAWTGAWTGW
WCAWTCAWTCA
Dap-seq
OMalley et al.(2016)
WUS1_colamp_a
0.740
0.702
WOX13
M02049_2.00
Arabidopsis thaliana
YTGATTGA
TCAATCAR
PBM
Weirauch et al.(2014)
pTH6461
0.623
0.474
WOX13
M00866_2.00
Arabidopsis thaliana
NNTGATTGAN
NTCAATCANN
PBM
Franco-Zorrilla et al.(2014)
WOX13
0.623
0.474
GRMZM2G038252
M02137_2.00
Zea mays
HTRATTGV
BCAATYAD
PBM
Weirauch et al.(2014)
pTH6141
0.623
0.474
For this family, TFs with SR scores >
0.599
will likely have a similar motif
DNA Binding Domains
Protein ID
Domain
From
To
Sequence
AT3G18010.1
Homeodomain
73
134
VSSRWNPTPDQLRVLEELYRQGTRTPSADHIQQITAQLRRYGKIEGKNVFYWFQNHKARERQ
Links
Other
Homeodomain
family TFs
Other
Arabidopsis thaliana
TFs
579 Related TFs
Name
Species
Gene ID
Motif Evidence
SR
Score
Action
Invalid Input OrderBy