SIX4 (Choloepus hoffmanni)
Homeodomain

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00046 (Homeobox) IPR001356 ENSCHOG00000005951 T207766_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
Six4
M00461_2.00
Mus musculus
NNKABMHNN

NNDKVTMNN
PBM
Berger et al.(2008)
Six4_2860
0.821 0.962
SIX4
M04939_2.00
Homo sapiens
NVYGATACVB

VBGTATCRBN
SELEX
Yin et al.(2017)
SIX4_eDBD_HT-SELEX
0.821 0.962
Six4
M09198_2.00
Mus musculus
DGDAABHNSASNNN

NNNSTSNDVTTHCH
Misc
Kulakovskiy et al.(2013)
SIX4_MOUSE.H11MO.0.C
0.821 0.962
SIX4
M10646_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$SIX4_Q3
0.821 0.962
SIX4
M04940_2.00
Homo sapiens
NBGTAWCRHN

NDYGWTACVN
SELEX
Yin et al.(2017)
SIX4_eDBD_Methyl-HT-SELEX
0.821 0.962
Six4
M00563_2.00
Drosophila melanogaster
NNDANMHNN

NNDKNTHNN
PBM
Busser et al.(2012a)
Six4
0.794 0.769
Six4
M06530_2.00
Drosophila melanogaster
TGABAC

GTVTCA
B1H
Mathelier et al.(2014)
MA0204.1
0.794 0.769
Six4
M06334_2.00
Drosophila melanogaster
WDDTGABAC

GTVTCAHHW
B1H
Zhu et al.(2011)
Six4_Cell_FBgn0027364
0.794 0.769
Six4
M06335_2.00
Drosophila melanogaster
NTGAKACB

VGTMTCAN
B1H
Zhu et al.(2011)
Six4_SOLEXA_2_FBgn0027364
0.794 0.769
Six4
M06336_2.00
Drosophila melanogaster
NNNTGABA

TVTCANNN
B1H
Zhu et al.(2011)
Six4_SOLEXA_FBgn0027364
0.794 0.769
SIX5
M08208_2.00
Homo sapiens
GARWTGTAGT

ACTACAWYTC
ChIP-seq
Contrino et al.(2012)
Mv121
0.793 0.750
SIX5
M08209_2.00
Homo sapiens
GGAGTTGT

ACAACTCC
ChIP-seq
Contrino et al.(2012)
Mv123
0.793 0.750
SIX5
M10738_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$SIX5_01
0.793 0.750
SIX5
M10739_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$SIX5_02
0.793 0.750
Six2
M00425_2.00
Mus musculus
NNAYMYNN

NNRKRTNN
PBM
Berger et al.(2008)
Six2_2307
0.674 0.712
Six1
M00512_2.00
Mus musculus
NNDATMYNNN

NNNRKATHNN
PBM
Berger et al.(2008)
Six1_0935
0.674 0.712
SIX1
M05094_2.00
Homo sapiens
NNYGATACVB

VBGTATCRNN
SELEX
Yin et al.(2017)
SIX1_eDBD_HT-SELEX
0.674 0.712
SIX1
M05096_2.00
Homo sapiens
NNYGATAYVB

VBRTATCRNN
SELEX
Yin et al.(2017)
SIX1_FL_HT-SELEX
0.674 0.712
SIX2
M05285_2.00
Homo sapiens
NNYGATACSB

VSGTATCRNN
SELEX
Yin et al.(2017)
SIX2_eDBD_HT-SELEX
0.674 0.712
SIX2
M05287_2.00
Homo sapiens
NSGTRWCRYN

NRYGWYACSN
SELEX
Yin et al.(2017)
SIX2_FL_HT-SELEX
0.674 0.712
SIX1
M08130_2.00
Homo sapiens
GWAACCTGANM

KNTCAGGTTWC
ChIP-seq
Mathelier et al.(2014)
MA1118.1
0.674 0.712
SIX2
M08133_2.00
Homo sapiens
NNNTGWAACCTGAKMH

DKMTCAGGTTWCANNN
ChIP-seq
Mathelier et al.(2014)
MA1119.1
0.674 0.712
SIX1
M09142_2.00
Homo sapiens
DGWAAYHTGABMYN

NRKVTCADRTTWCH
Misc
Kulakovskiy et al.(2013)
SIX1_HUMAN.H11MO.0.A
0.674 0.712
SIX2
M09157_2.00
Homo sapiens
DGWAAYHHGABMH

DKVTCDDRTTWCH
Misc
Kulakovskiy et al.(2013)
SIX2_HUMAN.H11MO.0.A
0.674 0.712
Six2
M09185_2.00
Mus musculus
DGWAAYHYRABMYB

VRKVTYRDRTTWCH
Misc
Kulakovskiy et al.(2013)
SIX2_MOUSE.H11MO.0.A
0.674 0.712
Six1
M09579_2.00
Mus musculus
GWAAYHTGABMH

DKVTCADRTTWC
Misc
Heinz et al.(2010)
Myoblast-Six1_GSE20150
0.674 0.712
SIX1
M10684_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$SIX1_Q3_01
0.674 0.712
SIX1
M10685_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$SIX1_Q3
0.674 0.712
SIX1
M05095_2.00
Homo sapiens
NNYGATABNB

VNVTATCRNN
SELEX
Yin et al.(2017)
SIX1_eDBD_Methyl-HT-SELEX
0.674 0.712
SIX1
M05097_2.00
Homo sapiens
NNYGATAYSB

VSRTATCRNN
SELEX
Yin et al.(2017)
SIX1_FL_Methyl-HT-SELEX
0.674 0.712
SIX2
M05286_2.00
Homo sapiens
NBRTATCRNN

NNYGATAYVN
SELEX
Yin et al.(2017)
SIX2_eDBD_Methyl-HT-SELEX
0.674 0.712
SIX2
M05288_2.00
Homo sapiens
VBRTAWCRNN

NNYGWTAYVB
SELEX
Yin et al.(2017)
SIX2_FL_Methyl-HT-SELEX
0.674 0.712
so
M02117_2.00
Drosophila melanogaster
NDATMYNNN

NNNRKATHN
PBM
Weirauch et al.(2014)
pTH5690
0.674 0.692
so
M03800_2.00
Drosophila melanogaster
NYGATAYB

VRTATCRN
SELEX
Nitta et al.(2015)
so_1
0.674 0.692
so
M03801_2.00
Drosophila melanogaster
YKATAYNNNYGATAY

RTATCRNNNRTATMR
SELEX
Nitta et al.(2015)
so_2
0.674 0.692
so
M03802_2.00
Drosophila melanogaster
YGATACGTATCR

YGATACGTATCR
SELEX
Nitta et al.(2015)
so_3
0.674 0.692
so
M03803_2.00
Drosophila melanogaster
RTATCRYGATAC

GTATCRYGATAY
SELEX
Nitta et al.(2015)
so_4
0.674 0.692
so
M06497_2.00
Drosophila melanogaster
TGATAC

GTATCA
B1H
Mathelier et al.(2014)
MA0246.1
0.674 0.692
so
M06268_2.00
Drosophila melanogaster
NRTGATA

TATCAYN
B1H
Zhu et al.(2011)
So_Cell_FBgn0003460
0.674 0.692
so
M06269_2.00
Drosophila melanogaster
NNNTGATA

TATCANNN
B1H
Zhu et al.(2011)
So_SOLEXA_FBgn0003460
0.674 0.692
ceh-34
M00672_2.00
Caenorhabditis elegans
NNNRDAWNNN

NNNWTHYNNN
PBM
Narasimhan et al.(2015)
pTH9708
0.601 0.577
For this family, TFs with SR scores > 0.599 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSCHOP00000005263 Homeodomain 220 271

Links

Other Homeodomain family TFs
Other Choloepus hoffmanni TFs

536 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action
BXY_0973100 Bursaphelenchus xylophilus BXY_0973100 I 0.000
BXY_1598800 Bursaphelenchus xylophilus BXY_1598800 N 0.000
CBG03687 Caenorhabditis briggsae CBG03687 I 0.000
CBG03688 Caenorhabditis briggsae CBG03688 I 0.000
CBG04789 Caenorhabditis briggsae CBG04789 I 0.000
CBG12152 Caenorhabditis briggsae CBG12152 I 0.000
CBG16375 Caenorhabditis briggsae CBG16375 I 0.000
CBG20699 Caenorhabditis briggsae CBG20699 I 0.000
CBN03440 Caenorhabditis brenneri CBN03440 I 0.000
CBN03769 Caenorhabditis brenneri CBN03769 I 0.000
CBN04619 Caenorhabditis brenneri CBN04619 I 0.000
CBN16902 Caenorhabditis brenneri CBN16902 I 0.000
CBN18264 Caenorhabditis brenneri CBN18264 I 0.000
CBN24070 Caenorhabditis brenneri CBN24070 I 0.000
CJA04414 Caenorhabditis japonica CJA04414 I 0.000
CJA07390 Caenorhabditis japonica CJA07390 I 0.000
CJA10576 Caenorhabditis japonica CJA10576 I 0.000
CRE07801 Caenorhabditis remanei CRE07801 I 0.000
CRE09011 Caenorhabditis remanei CRE09011 I 0.000
CRE17310 Caenorhabditis remanei CRE17310 I 0.000
CRE17354 Caenorhabditis remanei CRE17354 I 0.000
CRE17355 Caenorhabditis remanei CRE17355 I 0.000
CRE27174 Caenorhabditis remanei CRE27174 I 0.000
CRE27659 Caenorhabditis remanei CRE27659 I 0.000
EVEC_0001095701 Enterobius vermicularis EVEC_0001095701 I 0.000
EVEC_0001266201 Enterobius vermicularis EVEC_0001266201 I 0.000
GPLIN_000628500 Globodera pallida GPLIN_000628500 N 0.000
GPLIN_000805100 Globodera pallida GPLIN_000805100 N 0.000
L596_g27786 Steinernema carpocapsae L596_g27786 I 0.000
L596_g9106 Steinernema carpocapsae L596_g9106 I 0.000
L889_g10781 Steinernema feltiae L889_g10781 I 0.000
L889_g17146 Steinernema feltiae L889_g17146 I 0.000
L889_g9698 Steinernema feltiae L889_g9698 I 0.000
L889_g987 Steinernema feltiae L889_g987 I 0.000
L892_g10708 Steinernema scapterisci L892_g10708 I 0.000
L892_g8140 Steinernema scapterisci L892_g8140 I 0.000
L892_g8144 Steinernema scapterisci L892_g8144 I 0.000
L892_g8145 Steinernema scapterisci L892_g8145 I 0.000
L892_g8146 Steinernema scapterisci L892_g8146 N 0.000
L893_g2090 Steinernema glaseri L893_g2090 I 0.000
L893_g4569 Steinernema glaseri L893_g4569 I 0.000
L893_g9517 Steinernema glaseri L893_g9517 I 0.000
L898_g10723 Steinernema monticolum L898_g10723 I 0.000
L898_g18539 Steinernema monticolum L898_g18539 I 0.000
L898_g28806 Steinernema monticolum L898_g28806 I 0.000
L898_g9580 Steinernema monticolum L898_g9580 I 0.000
NECAME_01500 Necator americanus NECAME_01500 I 0.000
PPA08785 Pristionchus pacificus PPA08785 I 0.000
PPA10478 Pristionchus pacificus PPA10478 I 0.000
PPA29361 Pristionchus pacificus PPA29361 I 0.000
RSKR_0000313900 Rhabditophanes kr3021 RSKR_0000313900 N 0.000
scaffold1235-EXSNAP2012.2 Pristionchus exspectatus scaffold1235-EXSNAP2012.2 I 0.000
scaffold183-EXSNAP2012.18 Pristionchus exspectatus scaffold183-EXSNAP2012.18 I 0.000
scaffold260-EXSNAP2012.15 Pristionchus exspectatus scaffold260-EXSNAP2012.15 I 0.000
SMUV_0000801801 Syphacia muris SMUV_0000801801 I 0.000
SMUV_0000886001 Syphacia muris SMUV_0000886001 I 0.000
SMUV_0000909301 Syphacia muris SMUV_0000909301 I 0.000
nhr-12 Caenorhabditis elegans WBGene00003611 I 0.000
nhr-16 Caenorhabditis elegans WBGene00003615 I 0.000
nhr-28 Caenorhabditis elegans WBGene00003624 I 0.000
nhr-53 Caenorhabditis elegans WBGene00003643 I 0.000
nhr-70 Caenorhabditis elegans WBGene00003660 D 0.000
nhr-86 Caenorhabditis elegans WBGene00003676 D 0.000
nhr-109 Caenorhabditis elegans WBGene00003699 I 0.000
nhr-273 Caenorhabditis elegans WBGene00020460 I 0.000