ENSCSAVG00000006091 (Ciona savignyi)
Homeodomain

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00046 (Homeobox) IPR001356 ENSCSAVG00000006091 T208461_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
Nkx2-3
M00497_2.00
Mus musculus
NNRAGDRNN

NNYHCTYNN
PBM
Berger et al.(2008)
Nkx2-3_3435
0.855 0.965
NKX2-3
M05042_2.00
Homo sapiens
NNBAAGTGBN

NVCACTTVNN
SELEX
Yin et al.(2017)
NKX2-3_eDBD_HT-SELEX
0.855 0.965
NKX2-3
M05045_2.00
Homo sapiens
BNBAAGTGBN

NVCACTTVNV
SELEX
Yin et al.(2017)
NKX2-3_FL_HT-SELEX
0.855 0.965
NKX2-3
M05043_2.00
Homo sapiens
BNBAAGTGBN

NVCACTTVNV
SELEX
Yin et al.(2017)
NKX2-3_eDBD_Methyl-HT-SELEX_1
0.855 0.965
NKX2-3
M05044_2.00
Homo sapiens
SDYAACGHB

VDCGTTRHS
SELEX
Yin et al.(2017)
NKX2-3_eDBD_Methyl-HT-SELEX_2
0.855 0.965
NKX2-3
M05046_2.00
Homo sapiens
BNBAAGTGBN

NVCACTTVNV
SELEX
Yin et al.(2017)
NKX2-3_FL_Methyl-HT-SELEX_1
0.855 0.965
NKX2-3
M05047_2.00
Homo sapiens
SWYAACSHB

VDSGTTRWS
SELEX
Yin et al.(2017)
NKX2-3_FL_Methyl-HT-SELEX_2
0.855 0.965
NKX2-5
M00323_2.00
Homo sapiens
NWYAAGTGSNN

NNSCACTTRWN
PBM
Barrera et al.(2016)
NKX2-5_REF
0.853 0.912
Nkx2-5
M00404_2.00
Mus musculus
NNNRAGDRBN

NVYHCTYNNN
PBM
Berger et al.(2008)
Nkx2-5_3436
0.853 0.912
NKX2-5
M05346_2.00
Homo sapiens
BHYAAGTGBN

NVCACTTRDV
SELEX
Yin et al.(2017)
NKX2-5_FL_HT-SELEX
0.853 0.912
Nkx2-5
M02686_2.00
Mus musculus
WTAAKWK

MWMTTAW
SELEX
Mathelier et al.(2014)
MA0063.1
0.853 0.912
Nkx2-5
M08136_2.00
Mus musculus
SYTGAGWGSYH

DRSCWCTCARS
ChIP-seq
Mathelier et al.(2014)
MA0503.1
0.853 0.912
NKX2-5
M09163_2.00
Homo sapiens
BKRAGWGV

BCWCTYMV
Misc
Kulakovskiy et al.(2013)
NKX25_HUMAN.H11MO.0.B
0.853 0.912
Nkx2-5
M09177_2.00
Mus musculus
NBYBRAGTGS

SCACTYVRVN
Misc
Kulakovskiy et al.(2013)
NKX25_MOUSE.H11MO.0.A
0.853 0.912
Nkx2-5
M09567_2.00
Mus musculus
HBRAGWGBNN

NNVCWCTYVD
Misc
Heinz et al.(2010)
HL1-Nkx2.5.biotin_GSE21529
0.853 0.912
NKX2-5
M10742_2.00
Homo sapiens
TYAAGTG

CACTTRA
Transfac
Matys et al.(2006)
V$NKX25_01
0.853 0.912
NKX2-5
M10743_2.00
Homo sapiens
CWTAATTV

BAATTAWG
Transfac
Matys et al.(2006)
V$NKX25_02
0.853 0.912
NKX2-5
M10744_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$NKX25_Q5
0.853 0.912
NKX2-5
M10745_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$NKX25_Q6
0.853 0.912
NKX2-5
M05347_2.00
Homo sapiens
BTYAAGTGGN

NCCACTTRAV
SELEX
Yin et al.(2017)
NKX2-5_FL_Methyl-HT-SELEX_1
0.853 0.912
NKX2-5
M05348_2.00
Homo sapiens
BTYAACGAB

VTCGTTRAV
SELEX
Yin et al.(2017)
NKX2-5_FL_Methyl-HT-SELEX_2
0.853 0.912
NKX2-5
M00322_2.00
Homo sapiens
NNNRNNN

NNNYNNN
PBM
Barrera et al.(2016)
NKX2-5_R190C
0.853 0.895
NKX2-5
M00324_2.00
Homo sapiens
NHNNNNN

NNNNNDN
PBM
Barrera et al.(2016)
NKX2-5_T178M
0.853 0.895
NKX2-5
M00321_2.00
Homo sapiens
HNAAGTRBNN

NNVYACTTND
PBM
Barrera et al.(2016)
NKX2-5_R161P
0.848 0.895
ceh-28
M08210_2.00
Caenorhabditis elegans
AATCGATW

WATCGATT
ChIP-seq
Contrino et al.(2012)
Mw138
0.826 0.789
NKX2-5
M00320_2.00
Homo sapiens
NHBAAKWRN

NYWMTTVDN
PBM
Barrera et al.(2016)
NKX2-5_K183E
0.820 0.895
scro
M03854_2.00
Drosophila melanogaster
NNBRMGTGB

VCACKYVNN
SELEX
Nitta et al.(2015)
scro_1
0.806 0.842
Nkx2-6
M00496_2.00
Mus musculus
HYAAGTRBNN

NNVYACTTRD
PBM
Berger et al.(2008)
Nkx2-6_3437
0.805 0.842
ceh-24
M02181_2.00
Caenorhabditis elegans
NNRAKWRNN

NNYWMTYNN
PBM
Weirauch et al.(2014)
pTH6327
0.801 0.789
Nkx2-1
M00385_2.00
Mus musculus
NNRAGDRN

NYHCTYNN
PBM
Berger et al.(2008)
Titf1_1722
0.797 0.842
Nkx2-4
M00514_2.00
Mus musculus
NNRAGDRBNN

NNVYHCTYNN
PBM
Berger et al.(2008)
Nkx2-4_3074
0.797 0.842
NKX2-1
M09146_2.00
Homo sapiens
BTKGAGWGBN

NVCWCTCMAV
Misc
Kulakovskiy et al.(2013)
NKX21_HUMAN.H11MO.0.A
0.797 0.842
Nkx2-1
M09171_2.00
Mus musculus
NBTKGAGWGB

VCWCTCMAVN
Misc
Kulakovskiy et al.(2013)
NKX21_MOUSE.H11MO.0.A
0.797 0.842
Nkx2-1
M09563_2.00
Mus musculus
BTBRAGWGBH

DVCWCTYVAV
Misc
Heinz et al.(2010)
LungAC-Nkx2.1_GSE43252
0.797 0.842
NKX2-1
M10694_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$TITF1_Q3
0.797 0.842
NKX2-1
M10695_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$TTF1_Q5_01
0.797 0.842
NKX2-1
M10696_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$TTF1_Q5
0.797 0.842
NKX2-1
M10697_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$TTF1_Q6
0.797 0.842
tin
M00559_2.00
Drosophila melanogaster
NWYAAGTGGNN

NNCCACTTRWN
PBM
Busser et al.(2012a)
Tin
0.790 0.719
tin
M03809_2.00
Drosophila melanogaster
BTYAAGTGSN

NSCACTTRAV
SELEX
Nitta et al.(2015)
tin_1
0.790 0.719
tin
M06284_2.00
Drosophila melanogaster
BTYAAGTG

CACTTRAV
B1H
Zhu et al.(2011)
Tin_Cell_FBgn0004110
0.790 0.719
tin
M06285_2.00
Drosophila melanogaster
BCTCAAGTGSVN

NBSCACTTGAGV
B1H
Zhu et al.(2011)
tin_FlyReg_FBgn0004110
0.790 0.719
tin
M06286_2.00
Drosophila melanogaster
BWYAAGTR

YACTTRWV
B1H
Zhu et al.(2011)
Tin_SOLEXA_FBgn0004110
0.790 0.719
tin
M08421_2.00
Drosophila melanogaster
DBTCRAGTGS

SCACTYGAVH
ChIP-chip
Mathelier et al.(2014)
MA0247.2
0.790 0.719
Nkx2-9
M00520_2.00
Mus musculus
NNNRAGDRBN

NVYHCTYNNN
PBM
Berger et al.(2008)
Nkx2-9_3082
0.747 0.789
Nkx2-9
M00800_2.00
Mus musculus
NNRAGDRBNN

NNVYHCTYNN
PBM
Weirauch et al.(2013)
pTH2842
0.747 0.789
Nkx2-9
M09215_2.00
Mus musculus
BTCAAGKRB

VYMCTTGAV
Misc
Kulakovskiy et al.(2013)
NKX28_MOUSE.H11MO.0.C
0.747 0.789
Nkx2-2
M00438_2.00
Mus musculus
NNNRAGDRN

NYHCTYNNN
PBM
Berger et al.(2008)
Nkx2-2_2823
0.741 0.789
Nkx2-2
M09190_2.00
Mus musculus
NTBRAGWGBBN

NVVCWCTYVAN
Misc
Kulakovskiy et al.(2013)
NKX22_MOUSE.H11MO.0.A
0.741 0.789
NKX2-2
M10681_2.00
Homo sapiens
WTAAGTRBTT

AAVYACTTAW
Transfac
Matys et al.(2006)
V$NKX22_01
0.741 0.789
NKX2-2
M10682_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$NKX2B_Q3_01
0.741 0.789
NKX2-2
M10683_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$NKX2B_Q3
0.741 0.789
vnd
M06551_2.00
Drosophila melanogaster
WYTCAAGTR

YACTTGARW
B1H
Mathelier et al.(2014)
MA0253.1
0.741 0.772
vnd
M06377_2.00
Drosophila melanogaster
WYTCAAGTR

YACTTGARW
B1H
Zhu et al.(2011)
Vnd_Cell_FBgn0003986
0.741 0.772
vnd
M06378_2.00
Drosophila melanogaster
KYTSAAGWGY

RCWCTTSARM
B1H
Zhu et al.(2011)
vnd_FlyReg_FBgn0003986
0.741 0.772
vnd
M06379_2.00
Drosophila melanogaster
BTBAAGTR

YACTTVAV
B1H
Zhu et al.(2011)
Vnd_SOLEXA_FBgn0003986
0.741 0.772
vnd
M09683_2.00
Drosophila melanogaster
TCAAGTGB

VCACTTGA
Misc
Kulakovskiy et al.(2009)
vnd
0.741 0.772
NKX2-8
M00302_2.00
Homo sapiens
NNRAGDRB

VYHCTYNN
PBM
Barrera et al.(2016)
NKX2-8_REF
0.715 0.772
NKX2-8
M05149_2.00
Homo sapiens
BTSRAGTGBN

NVCACTYSAV
SELEX
Yin et al.(2017)
NKX2-8_FL_HT-SELEX
0.715 0.772
NKX2-8
M09145_2.00
Homo sapiens
BTCAAGKRB

VYMCTTGAV
Misc
Kulakovskiy et al.(2013)
NKX28_HUMAN.H11MO.0.C
0.715 0.772
NKX2-8
M05150_2.00
Homo sapiens
GCARTAACGACATC

GATGTCGTTAYTGC
SELEX
Yin et al.(2017)
NKX2-8_FL_Methyl-HT-SELEX_1
0.715 0.772
NKX2-8
M05151_2.00
Homo sapiens
BTSAAGTGBN

NVCACTTSAV
SELEX
Yin et al.(2017)
NKX2-8_FL_Methyl-HT-SELEX_2
0.715 0.772
NKX2-8
M05152_2.00
Homo sapiens
BTBAACGAB

VTCGTTVAV
SELEX
Yin et al.(2017)
NKX2-8_FL_Methyl-HT-SELEX_3
0.715 0.772
NKX2-8
M00301_2.00
Homo sapiens
NNRAKDRB

VYHMTYNN
PBM
Barrera et al.(2016)
NKX2-8_A94T
0.715 0.754
ceh-22
M00376_2.00
Caenorhabditis elegans
WBRAGTRBNN

NNVYACTYVW
PBM
Berger et al.(2006)
Ceh-22
0.709 0.702
Q24782_9CNID
M02206_2.00
Eleutheria dichotoma
TTAATTAA

TTAATTAA
PBM
Weirauch et al.(2014)
pTH5486
0.623 0.561
For this family, TFs with SR scores > 0.599 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSCSAVP00000010345 Homeodomain 371 427
ENSCSAVP00000010346 Homeodomain 149 205

Links

Other Homeodomain family TFs
Other Ciona savignyi TFs

824 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action
Alligator_sinensis_CCG003245.1 Alligator sinensis Alligator_sinensis_CCG003245.1 I 0.000
Cmyd_10015601 Chelonia mydas Cmyd_10015601 I 0.000
ZBTB7A Bos taurus ENSBTAG00000020117 I 0.000
ENSBTAP00000035733-D1 Bos grunniens ENSBTAP00000035733-D1 I 0.000
ZBTB7A Canis familiaris ENSCAFG00000024335 I 0.000
ZBTB7A Callithrix jacchus ENSCJAG00000036210 I 0.000
ENSCPOG00000024829 Cavia porcellus ENSCPOG00000024829 I 0.000
ENSCSAG00000010775 Chlorocebus sabaeus ENSCSAG00000010775 I 0.000
ENSFALG00000000874 Ficedula albicollis ENSFALG00000000874 I 0.000
ZBTB7A Homo sapiens ENSG00000178951 D 0.000
ENSMEUG00000005804 Macropus eugenii ENSMEUG00000005804 I 0.000
ZBTB7A Myotis lucifugus ENSMLUG00000008667 I 0.000
ENSMMUG00000019103 Macaca mulatta ENSMMUG00000019103 I 0.000
ZBTB7A Monodelphis domestica ENSMODG00000000778 I 0.000
ENSMPUG00000004703 Mustela putorius furo ENSMPUG00000004703 I 0.000
Zbtb7a Mus musculus ENSMUSG00000035011 D 0.000
ENSNLEG00000003007 Nomascus leucogenys ENSNLEG00000003007 I 0.000
ZBTB7A Ornithorhynchus anatinus ENSOANG00000006290 I 0.000
ZBTB7A Otolemur garnettii ENSOGAG00000033963 I 0.000
ENSPANG00000010574 Papio anubis ENSPANG00000010574 I 0.000
ENSPSIG00000017106 Pelodiscus sinensis ENSPSIG00000017106 I 0.000
ZBTB7A Pan troglodytes ENSPTRG00000010292 I 0.000
Zbtb7a Rattus norvegicus ENSRNOG00000020161 I 0.000
ZBTB7A Sus scrofa ENSSSCG00000029236 I 0.000
ZBTB7A Tursiops truncatus ENSTTRG00000006780 I 0.000
Myotis_brandtii_ZBTB7A_10016304 Myotis brandtii Myotis_brandtii_ZBTB7A_10016304 I 0.000
Ogr12162 Ophisaurus gracilis Ogr12162 I 0.000
Pvit_09830 Pogona vitticeps Pvit_09830 I 0.000