pitx1 (Danio rerio)
Homeodomain

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00046 (Homeobox) IPR001356 ENSDARG00000042785 T208619_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
PITX2
M00313_2.00
Homo sapiens
NWAAKHYN

NRDMTTWN
PBM
Barrera et al.(2016)
PITX2_REF
0.867 1.000
Pitx3
M00428_2.00
Mus musculus
NTAAKCYN

NRGMTTAN
PBM
Berger et al.(2008)
Pitx3_3497
0.867 1.000
Pitx2
M00440_2.00
Mus musculus
NTAATCCN

NGGATTAN
PBM
Berger et al.(2008)
Pitx2_2274
0.867 1.000
PITX3
M03111_2.00
Homo sapiens
NHTAATCCN

NGGATTADN
SELEX
Jolma et al.(2013)
PITX3_1
0.867 1.000
PITX2
M05229_2.00
Homo sapiens
NTAAKCCN

NGGMTTAN
SELEX
Yin et al.(2017)
PITX2_eDBD_HT-SELEX
0.867 1.000
PITX2
M05231_2.00
Homo sapiens
NTAATCCN

NGGATTAN
SELEX
Yin et al.(2017)
PITX2_FL_HT-SELEX
0.867 1.000
PITX3
M04997_2.00
Homo sapiens
NTAATCCN

NGGATTAN
SELEX
Yin et al.(2017)
PITX3_eDBD_HT-SELEX
0.867 1.000
PITX2
M10720_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$PITX2_Q2
0.867 1.000
PITX2
M10721_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$PITX2_Q4
0.867 1.000
PITX2
M10722_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$PITX2_Q6
0.867 1.000
PITX3
M10660_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$PITX3_Q2
0.867 1.000
PITX3
M10661_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$PITX3_Q3_01
0.867 1.000
PITX3
M10662_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$PITX3_Q3
0.867 1.000
PITX2
M00314_2.00
Homo sapiens
NTAATMYN

NRKATTAN
PBM
Barrera et al.(2016)
PITX2_T114P
0.867 1.000
PITX2
M05230_2.00
Homo sapiens
HTAATCCN

NGGATTAD
SELEX
Yin et al.(2017)
PITX2_eDBD_Methyl-HT-SELEX
0.867 1.000
PITX2
M05232_2.00
Homo sapiens
YTAATCCY

RGGATTAR
SELEX
Yin et al.(2017)
PITX2_FL_Methyl-HT-SELEX
0.867 1.000
PITX3
M04998_2.00
Homo sapiens
NTAATCCN

NGGATTAN
SELEX
Yin et al.(2017)
PITX3_eDBD_Methyl-HT-SELEX
0.867 1.000
PITX2
M00310_2.00
Homo sapiens
HTAATCYN

NRGATTAD
PBM
Barrera et al.(2016)
PITX2_L100Q
0.867 0.982
Pitx1
M00415_2.00
Mus musculus
NTAATCYNN

NNRGATTAN
PBM
Berger et al.(2008)
Pitx1_2312
0.867 0.965
PITX1
M03082_2.00
Homo sapiens
NHTAATCCN

NGGATTADN
SELEX
Jolma et al.(2013)
PITX1_1
0.867 0.965
PITX1
M03083_2.00
Homo sapiens
NHTAATCCN

NGGATTADN
SELEX
Jolma et al.(2013)
PITX1_2
0.867 0.965
PITX1
M03084_2.00
Homo sapiens
HTAATCCN

NGGATTAD
SELEX
Jolma et al.(2013)
PITX1_3
0.867 0.965
PITX1
M04928_2.00
Homo sapiens
NTAATCCN

NGGATTAN
SELEX
Yin et al.(2017)
PITX1_eDBD_HT-SELEX
0.867 0.965
PITX1
M04930_2.00
Homo sapiens
NTAATCCN

NGGATTAN
SELEX
Yin et al.(2017)
PITX1_FL_HT-SELEX
0.867 0.965
Pitx1
M09182_2.00
Mus musculus
NYWAAKCCYH

DRGGMTTWRN
Misc
Kulakovskiy et al.(2013)
PITX1_MOUSE.H11MO.0.C
0.867 0.965
PITX1
M10640_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$PITX1_Q4
0.867 0.965
PITX1
M10641_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$PITX1_Q6
0.867 0.965
PITX1
M04929_2.00
Homo sapiens
NTAAKCCN

NGGMTTAN
SELEX
Yin et al.(2017)
PITX1_eDBD_Methyl-HT-SELEX
0.867 0.965
PITX1
M04931_2.00
Homo sapiens
HTAATCCN

NGGATTAD
SELEX
Yin et al.(2017)
PITX1_FL_Methyl-HT-SELEX
0.867 0.965
Ptx1
M02123_2.00
Drosophila melanogaster
NTAATCYNN

NNRGATTAN
PBM
Weirauch et al.(2014)
pTH5644
0.866 0.947
Ptx1
M00562_2.00
Drosophila melanogaster
NYTAATCCBN

NVGGATTARN
PBM
Busser et al.(2012a)
Ptx1
0.866 0.947
Ptx1
M03842_2.00
Drosophila melanogaster
NTAATCCN

NGGATTAN
SELEX
Nitta et al.(2015)
Ptx1_1
0.866 0.947
Ptx1
M03843_2.00
Drosophila melanogaster
NTAATCCN

NGGATTAN
SELEX
Nitta et al.(2015)
Ptx1_2
0.866 0.947
Ptx1
M03844_2.00
Drosophila melanogaster
NCGHTAATCCN

NGGATTADCGN
SELEX
Nitta et al.(2015)
Ptx1_3
0.866 0.947
Ptx1
M06521_2.00
Drosophila melanogaster
YTAATCC

GGATTAR
B1H
Mathelier et al.(2014)
MA0201.1
0.866 0.947
Ptx1
M06319_2.00
Drosophila melanogaster
YTAATCC

GGATTAR
B1H
Zhu et al.(2011)
Ptx1_Cell_FBgn0020912
0.866 0.947
Ptx1
M06320_2.00
Drosophila melanogaster
NYTAATCC

GGATTARN
B1H
Zhu et al.(2011)
Ptx1_SOLEXA_FBgn0020912
0.866 0.947
PITX2
M00311_2.00
Homo sapiens
TTAATCCY

RGGATTAA
PBM
Barrera et al.(2016)
PITX2_R108H
0.862 0.982
CBG01820
M01241_2.00
Caenorhabditis briggsae
NTAATCCN

NGGATTAN
PBM
Lambert et al.(2019)
pTH11454
0.856 0.825
PITX2
M00312_2.00
Homo sapiens
NNNTATWAATTNN

NNAATTWATANNN
PBM
Barrera et al.(2016)
PITX2_R130W
0.833 0.982
Gsc
M02120_2.00
Drosophila melanogaster
NTAATCYN

NRGATTAN
PBM
Weirauch et al.(2014)
pTH5511
0.763 0.614
Gsc
M03817_2.00
Drosophila melanogaster
TAATCCB

VGGATTA
SELEX
Nitta et al.(2015)
Gsc_1
0.763 0.614
Gsc
M03818_2.00
Drosophila melanogaster
TAATCGGATTA

TAATCCGATTA
SELEX
Nitta et al.(2015)
Gsc_2
0.763 0.614
Gsc
M03819_2.00
Drosophila melanogaster
TAATCYNHTAATCBN

NVGATTADNRGATTA
SELEX
Nitta et al.(2015)
Gsc_3
0.763 0.614
Gsc
M03820_2.00
Drosophila melanogaster
TAATCGGATTA

TAATCCGATTA
SELEX
Nitta et al.(2015)
Gsc_4
0.763 0.614
Gsc
M03821_2.00
Drosophila melanogaster
TAATCYNWTWATCYB

VRGATWAWNRGATTA
SELEX
Nitta et al.(2015)
Gsc_5
0.763 0.614
Gsc
M05873_2.00
Drosophila melanogaster
TAATCSNHTWA

TWADNSGATTA
SMiLE-seq
Isakova et al.(2017)
Gsc
0.763 0.614
Gsc
M06509_2.00
Drosophila melanogaster
TAATCY

RGATTA
B1H
Mathelier et al.(2014)
MA0190.1
0.763 0.614
Gsc
M06297_2.00
Drosophila melanogaster
VNTAATCY

RGATTANB
B1H
Zhu et al.(2011)
Gsc_Cell_FBgn0010323
0.763 0.614
Gsc
M06298_2.00
Drosophila melanogaster
NTAATCY

RGATTAN
B1H
Zhu et al.(2011)
Gsc_SOLEXA_FBgn0010323
0.763 0.614
Dmbx1
M00441_2.00
Mus musculus
NTAATCYNN

NNRGATTAN
PBM
Berger et al.(2008)
Dmbx1_2277
0.755 0.667
DMBX1
M03236_2.00
Homo sapiens
NHTAATCCBN

NVGGATTADN
SELEX
Jolma et al.(2013)
DMBX1_1
0.755 0.667
DMBX1
M05383_2.00
Homo sapiens
NTAATCSN

NSGATTAN
SELEX
Yin et al.(2017)
DMBX1_eDBD_HT-SELEX
0.755 0.667
DMBX1
M05384_2.00
Homo sapiens
HTAATCCN

NGGATTAD
SELEX
Yin et al.(2017)
DMBX1_eDBD_Methyl-HT-SELEX
0.755 0.667
ceh-53
M00679_2.00
Caenorhabditis elegans
HTAATCYN

NRGATTAD
PBM
Narasimhan et al.(2015)
pTH10699
0.751 0.544
GSC2
M03080_2.00
Homo sapiens
NHTAATCCBH

DVGGATTADN
SELEX
Jolma et al.(2013)
GSC2_1
0.742 0.632
GSC2
M04920_2.00
Homo sapiens
NTAATNNN

NNNATTAN
SELEX
Yin et al.(2017)
GSC2_eDBD_HT-SELEX
0.742 0.632
GSC2
M04921_2.00
Homo sapiens
NTAATCYN

NRGATTAN
SELEX
Yin et al.(2017)
GSC2_eDBD_Methyl-HT-SELEX
0.742 0.632
Gsc
M00411_2.00
Mus musculus
NNTAATYBN

NVRATTANN
PBM
Berger et al.(2008)
Gsc_2327
0.741 0.579
GSC
M03146_2.00
Homo sapiens
NHTAATCCNH

DNGGATTADN
SELEX
Jolma et al.(2013)
GSC_1
0.741 0.579
GSC
M05134_2.00
Homo sapiens
NTAATCCB

VGGATTAN
SELEX
Yin et al.(2017)
GSC_eDBD_HT-SELEX
0.741 0.579
GSC
M05136_2.00
Homo sapiens
HTAATCCN

NGGATTAD
SELEX
Yin et al.(2017)
GSC_FL_HT-SELEX
0.741 0.579
gsc
M09584_2.00
Xenopus tropicalis
NTAATCYN

NRGATTAN
Misc
Heinz et al.(2010)
FrogEmbryos-GSC_DRA000576
0.741 0.579
GSC
M05135_2.00
Homo sapiens
HTAATCCB

VGGATTAD
SELEX
Yin et al.(2017)
GSC_eDBD_Methyl-HT-SELEX
0.741 0.579
GSC
M05137_2.00
Homo sapiens
HTAATCCN

NGGATTAD
SELEX
Yin et al.(2017)
GSC_FL_Methyl-HT-SELEX
0.741 0.579
Otx1
M00396_2.00
Mus musculus
NTAAKCYN

NRGMTTAN
PBM
Berger et al.(2008)
Otx1_2325
0.731 0.614
Otx2
M00418_2.00
Mus musculus
NTAAKMBN

NVKMTTAN
PBM
Berger et al.(2008)
Otx2_3441
0.731 0.614
OTX1
M03116_2.00
Homo sapiens
NNTAAKCGGATTANN

NNTAATCCGMTTANN
SELEX
Jolma et al.(2013)
OTX1_1
0.731 0.614
OTX1
M03117_2.00
Homo sapiens
NTAATCSB

VSGATTAN
SELEX
Jolma et al.(2013)
OTX1_2
0.731 0.614
OTX2
M03197_2.00
Homo sapiens
NHTAAKCGGATTANN

NNTAATCCGMTTADN
SELEX
Jolma et al.(2013)
OTX2_1
0.731 0.614
OTX2
M03198_2.00
Homo sapiens
HTAATCCB

VGGATTAD
SELEX
Jolma et al.(2013)
OTX2_2
0.731 0.614
Otx1
M03249_2.00
Mus musculus
NNTAAKCGGATTANN

NNTAATCCGMTTANN
SELEX
Jolma et al.(2013)
Otx1_1
0.731 0.614
Otx1
M03250_2.00
Mus musculus
NTAATCCN

NGGATTAN
SELEX
Jolma et al.(2013)
Otx1_2
0.731 0.614
oc
M03808_2.00
Drosophila melanogaster
HTAATCCB

VGGATTAD
SELEX
Nitta et al.(2015)
oc_1
0.731 0.614
OTX1
M05022_2.00
Homo sapiens
NTAATCCN

NGGATTAN
SELEX
Yin et al.(2017)
OTX1_eDBD_HT-SELEX
0.731 0.614
OTX1
M05024_2.00
Homo sapiens
NTAATCCNNN

NNNGGATTAN
SELEX
Yin et al.(2017)
OTX1_FL_HT-SELEX
0.731 0.614
OTX2
M05251_2.00
Homo sapiens
NTAATCCN

NGGATTAN
SELEX
Yin et al.(2017)
OTX2_FL_HT-SELEX
0.731 0.614
oc
M06502_2.00
Drosophila melanogaster
TAATCC

GGATTA
B1H
Mathelier et al.(2014)
MA0234.1
0.731 0.614
oc
M06282_2.00
Drosophila melanogaster
WTAATCC

GGATTAW
B1H
Zhu et al.(2011)
Oc_Cell_FBgn0004102
0.731 0.614
oc
M06283_2.00
Drosophila melanogaster
NTAATCCB

VGGATTAN
B1H
Zhu et al.(2011)
Oc_SOLEXA_FBgn0004102
0.731 0.614
OTX2
M09153_2.00
Homo sapiens
BYTAATCCYYN

NRRGGATTARV
Misc
Kulakovskiy et al.(2013)
OTX2_HUMAN.H11MO.0.A
0.731 0.614
Otx2
M09183_2.00
Mus musculus
HTAATCCYNYNN

NNRNRGGATTAD
Misc
Kulakovskiy et al.(2013)
OTX2_MOUSE.H11MO.0.A
0.731 0.614
Otx2
M09569_2.00
Mus musculus
NHTAATCCHB

VDGGATTADN
Misc
Heinz et al.(2010)
EpiLC-Otx2_GSE56098
0.731 0.614
oc
M09681_2.00
Drosophila melanogaster
HTAATCCN

NGGATTAD
Misc
Kulakovskiy et al.(2009)
oc
0.731 0.614
OTX1
M10673_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$OTX1_Q5
0.731 0.614
OTX2
M10727_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$OTX2_Q3_01
0.731 0.614
OTX2
M10728_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$OTX2_Q3
0.731 0.614
OTX1
M05023_2.00
Homo sapiens
NTAATCCN

NGGATTAN
SELEX
Yin et al.(2017)
OTX1_eDBD_Methyl-HT-SELEX
0.731 0.614
OTX1
M05025_2.00
Homo sapiens
HTAATCCNHN

NDNGGATTAD
SELEX
Yin et al.(2017)
OTX1_FL_Methyl-HT-SELEX
0.731 0.614
OTX2
M05252_2.00
Homo sapiens
NTAATCCN

NGGATTAN
SELEX
Yin et al.(2017)
OTX2_FL_Methyl-HT-SELEX
0.731 0.614
CRX
M00274_2.00
Homo sapiens
NMTAATCCSN

NSGGATTAKN
PBM
Barrera et al.(2016)
CRX_REF
0.726 0.614
Crx
M00489_2.00
Mus musculus
NWAAKMBN

NVKMTTWN
PBM
Berger et al.(2008)
Crx_3485
0.726 0.614
CRX
M04949_2.00
Homo sapiens
NTAATCCN

NGGATTAN
SELEX
Yin et al.(2017)
CRX_FL_HT-SELEX
0.726 0.614
Crx
M08139_2.00
Mus musculus
YTAATCCYCYY

RRGRGGATTAR
ChIP-seq
Mathelier et al.(2014)
MA0467.1
0.726 0.614
CRX
M09132_2.00
Homo sapiens
BYTAATCCBHYYN

NRRDVGGATTARV
Misc
Kulakovskiy et al.(2013)
CRX_HUMAN.H11MO.0.B
0.726 0.614
Crx
M09208_2.00
Mus musculus
BYTAATCCBHYYN

NRRDVGGATTARV
Misc
Kulakovskiy et al.(2013)
CRX_MOUSE.H11MO.0.A
0.726 0.614
Crx
M09577_2.00
Mus musculus
NYTAATCC

GGATTARN
Misc
Heinz et al.(2010)
Retina-Crx_GSE20012
0.726 0.614
CRX
M10647_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$CRX_Q4_01
0.726 0.614
CRX
M10648_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$CRX_Q4_02
0.726 0.614
CRX
M00275_2.00
Homo sapiens
NMTAATCCSN

NSGGATTAKN
PBM
Barrera et al.(2016)
CRX_V66I
0.726 0.614
CRX
M04950_2.00
Homo sapiens
HTAATCCN

NGGATTAD
SELEX
Yin et al.(2017)
CRX_FL_Methyl-HT-SELEX
0.726 0.614
ceh-37
M00674_2.00
Caenorhabditis elegans
HTAATCYN

NRGATTAD
PBM
Narasimhan et al.(2015)
pTH10716
0.724 0.509
CRX
M00273_2.00
Homo sapiens
NNYTAATCCVN

NBGGATTARNN
PBM
Barrera et al.(2016)
CRX_R90W
0.716 0.596
NEMVEDRAFT_v1g113057
M02144_2.00
Nematostella vectensis
NYTAATCCBN

NVGGATTARN
PBM
Weirauch et al.(2014)
pTH6135
0.713 0.474
HBX4_ECHGR
M02195_2.00
Echinococcus granulosus
NHTAATCYNN

NNRGATTADN
PBM
Weirauch et al.(2014)
pTH6301
0.709 0.526
CRX
M00270_2.00
Homo sapiens
NWDAKNN

NNMTHWN
PBM
Barrera et al.(2016)
CRX_E80A
0.706 0.596
ceh-36
M00673_2.00
Caenorhabditis elegans
NWAATCYN

NRGATTWN
PBM
Narasimhan et al.(2015)
pTH10730
0.706 0.526
CRX
M00271_2.00
Homo sapiens
NHDAKNN

NNMTHDN
PBM
Barrera et al.(2016)
CRX_R41Q
0.694 0.596
CRX
M00272_2.00
Homo sapiens
NNHNATNN

NNATNDNN
PBM
Barrera et al.(2016)
CRX_R41W
0.694 0.596
DPRX
M03237_2.00
Homo sapiens
NHTAATCYNN

NNRGATTADN
SELEX
Jolma et al.(2013)
DPRX_1
0.656 0.421
DPRX
M03238_2.00
Homo sapiens
NRGMTAATCYN

NRGATTAKCYN
SELEX
Jolma et al.(2013)
DPRX_2
0.656 0.421
DPRX
M05388_2.00
Homo sapiens
VGMTAATCYN

NRGATTAKCB
SELEX
Yin et al.(2017)
DPRX_eDBD_HT-SELEX
0.656 0.421
DPRX
M05389_2.00
Homo sapiens
AGATMATCYN

NRGATKATCT
SELEX
Yin et al.(2017)
DPRX_eDBD_Methyl-HT-SELEX
0.656 0.421
dharma
M02080_2.00
Danio rerio
NNRAKCY

RGMTYNN
PBM
Weirauch et al.(2014)
pTH6530
0.631 0.491
For this family, TFs with SR scores > 0.599 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSDARP00000062802 Homeodomain 59 115
ENSDARP00000133023 Homeodomain 59 115

Links

Other Homeodomain family TFs
Other Danio rerio TFs

1130 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action
A1O3_05101 Capronia epimyces A1O3_05101 N 0.000
SAPIO_CDS7559 Scedosporium apiospermum SAPIO_CDS7559 N 0.000
SBOR_4214 Sclerotinia borealis SBOR_4214 N 0.000
SMAC_04680 Sordaria macrospora SMAC_04680 N 0.000
SS1G_08511 Sclerotinia sclerotiorum SS1G_08511 N 0.000
TRIREDRAFT_104141 Trichoderma reesei TRIREDRAFT_104141 N 0.000
TRIVIDRAFT_89106 Trichoderma virens TRIVIDRAFT_89106 N 0.000
TSTA_064910 Talaromyces stipitatus TSTA_064910 N 0.000
Z518_02964 Rhinocladiella mackenziei Z518_02964 N 0.000
Z519_11846 Cladophialophora bantiana Z519_11846 N 0.000
e_gw1.18.2010.1 Nectria haematococca e_gw1.18.2010.1 N 0.000
e_gw1.3.1226.1 Neurospora discreta e_gw1.3.1226.1 N 0.000
NCU06560 Neurospora crassa NCU06560 N 0.000
PVAR5_5807 Byssochlamys spectabilis PVAR5_5807 N 0.000
PV11_03110 Exophiala sideris PV11_03110 N 0.000
PV06_09082 Exophiala oligosperma PV06_09082 N 0.000
A1O9_11043 Exophiala aquamarina A1O9_11043 N 0.000
ACRE_040010 Acremonium chrysogenum ACRE_040010 N 0.000
BBA_02879 Beauveria bassiana BBA_02879 N 0.000
CMQ_4120 Grosmannia clavigera CMQ_4120 N 0.000
HMPREF1120_00913 Exophiala dermatitidis HMPREF1120_00913 N 0.000
HMPREF1541_10059 Cyphellophora europaea HMPREF1541_10059 N 0.000
MAPG_00470 Magnaporthe poae MAPG_00470 N 0.000
MGG_01688 Magnaporthe oryzae MGG_01688 N 0.000
NEUTE1DRAFT_116303 Neurospora tetrasperma NEUTE1DRAFT_116303 N 0.000
PFICI_05442 Pestalotiopsis fici PFICI_05442 N 0.000
PMAA_032590 Talaromyces marneffei PMAA_032590 N 0.000
PV04_09247 Capronia semiimmersa PV04_09247 N 0.000
PMAA_032590 Penicillium marneffei PMAA_032590 N 0.000