NKX3-2 (Homo sapiens)
Homeodomain

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00046 (Homeobox) IPR001356 ENSG00000109705 T209803_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
This gene encodes a member of the NK family of homeobox-containing proteins. The encoded protein may play a role in skeletal development. [provided by RefSeq, Jul 2008]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
NKX3-2
M05012_2.00
Homo sapiens
NNTAAGTGSN

NSCACTTANN
SELEX
Yin et al.(2017)
NKX3-2_eDBD_HT-SELEX
(Direct) (Direct)
NKX3-2
M05013_2.00
Homo sapiens
NNTAAGTGBN

NVCACTTANN
SELEX
Yin et al.(2017)
NKX3-2_eDBD_Methyl-HT-SELEX_1
(Direct) (Direct)
NKX3-2
M05014_2.00
Homo sapiens
NTAACGHB

VDCGTTAN
SELEX
Yin et al.(2017)
NKX3-2_eDBD_Methyl-HT-SELEX_2
(Direct) (Direct)
NKX3-2
M09138_2.00
Homo sapiens
TTAAGTGBNH

DNVCACTTAA
Misc
Kulakovskiy et al.(2013)
NKX32_HUMAN.H11MO.0.C
(Direct) (Direct)
NKX3-2
M10663_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$NKX32_01
(Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
Nkx3-2
M00506_2.00
Mus musculus
NNRAGDRNN

NNYHCTYNN
PBM
Berger et al.(2008)
Bapx1_2343
0.867 1.000
Nkx3-2
M09212_2.00
Mus musculus
TTAAGTGBNH

DNVCACTTAA
Misc
Kulakovskiy et al.(2013)
NKX32_MOUSE.H11MO.0.B
0.867 1.000
bap
M00560_2.00
Drosophila melanogaster
NDAAGTRBNN

NNVYACTTHN
PBM
Busser et al.(2012a)
Bap
0.855 0.877
bap
M02119_2.00
Drosophila melanogaster
NYTAAGTRSNN

NNSYACTTARN
PBM
Weirauch et al.(2014)
pTH5945
0.855 0.877
bap
M03812_2.00
Drosophila melanogaster
NNTAAGTGBN

NVCACTTANN
SELEX
Nitta et al.(2015)
bap_1
0.855 0.877
bap
M06504_2.00
Drosophila melanogaster
TTAAGTR

YACTTAA
B1H
Mathelier et al.(2014)
MA0211.1
0.855 0.877
bap
M06287_2.00
Drosophila melanogaster
NBTTAAGTRN

NYACTTAAVN
B1H
Zhu et al.(2011)
Bap_Cell_FBgn0004862
0.855 0.877
bap
M06288_2.00
Drosophila melanogaster
NYTAAKTR

YAMTTARN
B1H
Zhu et al.(2011)
Bap_SOLEXA_FBgn0004862
0.855 0.877
Nkx3-1
M00170_2.00
Mus musculus
NDAAGTRBNN

NNVYACTTHN
PBM
Badis et al.(2009)
Nkx3-1_2923
0.838 0.842
Nkx3-1
M00420_2.00
Mus musculus
NNAAGTRBNN

NNVYACTTNN
PBM
Berger et al.(2008)
Nkx3-1_2923
0.838 0.842
NKX3-1
M05255_2.00
Homo sapiens
NNTAAGTGSN

NSCACTTANN
SELEX
Yin et al.(2017)
NKX3-1_eDBD_HT-SELEX
0.838 0.842
NKX3-1
M09154_2.00
Homo sapiens
NYDAAGTGBYWD

HWRVCACTTHRN
Misc
Kulakovskiy et al.(2013)
NKX31_HUMAN.H11MO.0.C
0.838 0.842
Nkx3-1
M09184_2.00
Mus musculus
NYDAAGTGBYWD

HWRVCACTTHRN
Misc
Kulakovskiy et al.(2013)
NKX31_MOUSE.H11MO.0.C
0.838 0.842
NKX3-1
M09559_2.00
Homo sapiens
BTRAGTRBYY

RRVYACTYAV
Misc
Heinz et al.(2010)
LNCaP-Nkx3.1_GSE28264
0.838 0.842
NKX3-1
M10729_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
P$GT1_Q6_01
0.838 0.842
NKX3-1
M10730_2.00
Homo sapiens
NWWTAAGTATWH

DWATACTTAWWN
Transfac
Matys et al.(2006)
V$NKX3A_01
0.838 0.842
NKX3-1
M10731_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$NKX3A_Q3
0.838 0.842
NKX3-1
M05256_2.00
Homo sapiens
NNTAAGTGBN

NVCACTTANN
SELEX
Yin et al.(2017)
NKX3-1_eDBD_Methyl-HT-SELEX_1
0.838 0.842
NKX3-1
M05257_2.00
Homo sapiens
NTAAYSWB

VWSRTTAN
SELEX
Yin et al.(2017)
NKX3-1_eDBD_Methyl-HT-SELEX_2
0.838 0.842
ENSCING00000007395
M02076_2.00
Ciona intestinalis
NNNDWNWR

YWNWHNNN
PBM
Weirauch et al.(2014)
pTH5922
0.825 0.684
For this family, TFs with SR scores > 0.599 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000371875 Homeodomain 207 263

Links

Other Homeodomain family TFs
Other Homo sapiens TFs

222 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action