CIS-BP Database: Catalog of Inferred Sequence Binding Preferences
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HHEX
(
Homo sapiens
)
Homeodomain
TF Information
Pfam ID
Interpro ID
Gene ID
CIS-BP ID
Sequence source
Animal TF db
PF00046 (Homeobox)
IPR001356
ENSG00000152804
T209863_2.00
Ensembl (2018-Dec-8)
Link out
NCBI Gene Info:
This gene encodes a member of the homeobox family of transcription factors, many of which are involved in developmental processes. Expression in specific hematopoietic lineages suggests that this protein may play a role in hematopoietic differentiation. [provided by RefSeq, Jul 2008]
Directly determined binding motifs
Name/Motif ID
Species
Forward
Reverse
Type/Study/Study ID
SR
Score
DBD
Identity
No direct experiments
Motifs from related TFs
Name/Motif ID
Species
Forward
Reverse
Type/Study/Study ID
SR
Score
DBD
Identity
pha-2
M02184_2.00
Caenorhabditis elegans
NNNATNDNNN
NNNHNATNNN
PBM
Weirauch et al.(2014)
pTH6423
0.708
0.772
HHEX
M06541_2.00
Drosophila melanogaster
WYBAATWA
TWATTVRW
B1H
Mathelier et al.(2014)
MA0183.1
0.683
0.667
HHEX
M06358_2.00
Drosophila melanogaster
WYBAATWA
TWATTVRW
B1H
Zhu et al.(2011)
CG7056_Cell_FBgn0038852
0.683
0.667
HHEX
M06359_2.00
Drosophila melanogaster
NYBAATWR
YWATTVRN
B1H
Zhu et al.(2011)
CG7056_SOLEXA_FBgn0038852
0.683
0.667
For this family, TFs with SR scores >
0.599
will likely have a similar motif
DNA Binding Domains
Protein ID
Domain
From
To
Sequence
ENSP00000282728
Homeodomain
138
194
KGGQVRFSNDQTIELEKKFETQKYLSPPERKRLAKMLQLSERQVKTWFQNRRAKWRR
ENSP00000447953
Homeodomain
1
22
MLQLSERQVKTWFQNRRAKWRR
ENSP00000450017
Homeodomain
1
22
MLQLSERQVKTWFQNRRAKWRR
Links
Other
Homeodomain
family TFs
Other
Homo sapiens
TFs
1056 Related TFs
Name
Species
Gene ID
Motif Evidence
SR
Score
Action
Invalid Input OrderBy